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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D4A5D4_RAT (D4A5D4)

Summary

This is the summary of UniProt entry D4A5D4_RAT (D4A5D4).

Description: Microtubule crosslinking factor 1 {ECO:0000313|Ensembl:ENSRNOP00000042113}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 1611 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
coiled_coil n/a 1 64
disorder n/a 2 3
disorder n/a 12 13
disorder n/a 15 17
disorder n/a 22 26
coiled_coil n/a 93 141
disorder n/a 101 119
disorder n/a 121 123
low_complexity n/a 134 150
disorder n/a 137 139
Pfam SOGA 162 256
coiled_coil n/a 170 204
disorder n/a 181 193
disorder n/a 198 200
disorder n/a 202 229
low_complexity n/a 224 239
coiled_coil n/a 232 266
disorder n/a 257 297
Pfam SOGA 291 383
coiled_coil n/a 292 326
disorder n/a 313 315
disorder n/a 324 329
disorder n/a 334 335
disorder n/a 338 364
coiled_coil n/a 359 379
disorder n/a 394 466
coiled_coil n/a 475 495
disorder n/a 479 480
disorder n/a 486 488
disorder n/a 491 493
disorder n/a 496 531
coiled_coil n/a 529 549
low_complexity n/a 563 577
disorder n/a 580 591
disorder n/a 600 601
disorder n/a 614 625
disorder n/a 627 633
disorder n/a 635 640
coiled_coil n/a 673 693
disorder n/a 675 679
disorder n/a 681 683
disorder n/a 714 789
coiled_coil n/a 804 824
disorder n/a 818 820
disorder n/a 850 873
Pfam DUF4482 886 1009
coiled_coil n/a 896 934
disorder n/a 930 931
disorder n/a 937 968
disorder n/a 970 973
disorder n/a 981 989
low_complexity n/a 1000 1017
disorder n/a 1002 1009
disorder n/a 1011 1028
disorder n/a 1031 1035
disorder n/a 1051 1076
disorder n/a 1089 1234
low_complexity n/a 1130 1142
disorder n/a 1240 1241
disorder n/a 1251 1276
disorder n/a 1279 1353
low_complexity n/a 1338 1347
disorder n/a 1356 1357
disorder n/a 1364 1504
disorder n/a 1507 1611
low_complexity n/a 1578 1590
low_complexity n/a 1597 1609

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D4A5D4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEELRSENDY LKDELDELRA EMEEMRDSYL EEDGYQLQEL RRELDRANKN
50
51
CRILQYRLRK AEQKSLKVAE TGQVDGELIR SLEQDLKVAK DVSVRLHHEL
100
101
ETVEEKRAKA EDDNETLRQH MIEVEISRQA LQNELERLRE SSLKRRGSRE
150
151
IYKEKKLVNQ DDSADLKCQL QFAKEEASLM RKKMAKLGRE KDELEQELQK
200
201
YKSLYGDVDS PLPTGEAGGP PSTREAELKL RLKLVEEEAS ILGRKIVELE
250
251
VENRGLKAEM EDIRVQHERE GTSRDHVPGI PTSPFGDSME SSTELRRHLQ
300
301
FVEEEAELLR RSISEIEDHN RQLTHELSKF KFEPHQESGW LGDGVSKGPG
350
351
ASAPLQEELK SARLQIDELS GKVLKLQCEN RLLLSNAQRC DLAAHLGLRA
400
401
PSPRDSDAES DAGKKESDGE EGRLPQPKRE GPVGGESDSE DMFEKTSGFG
450
451
SGKPSEASEP CPTELLRVRE DTECLVTMKL EAQRLERTVE RLISDTDGFI
500
501
RDSGLRGNGS ASPGVQGEGE GSLNEPHLLE TINGRMKAFR KELQAFLEQM
550
551
SRIVDGLSPL SHLTESSSFL STVTSVSRDS PIGTLGKELG PDLQSKLREQ
600
601
LEWQLGQDRG DEREGLRLRA TRELHRHADG DSGSHGLGGQ SCFNLEMEED
650
651
HLYALRWKEL EMHSLALQNT LHKRTWSDEK NMLQQELRSL KQNIFLFYVK
700
701
LRWLLKHWRQ GKQMEEGGED FAESEHPENV PGLAELGVQG GHRTDGTDQE
750
751
GTDRGCGLPM GEPAPHSPVQ MSEHGSRLPT ADGGPLSKQV VENQQLFRAL
800
801
KALLEDFRSE LREDEHARLR LQQQYASDKA AWDVEWAVLK CRLEQLEEKT
850
851
EKSLGELDSS AEGKGALKKE REVHQKLLAD SHGLVMDLRW QIHHREKNWN
900
901
REKVELLERL DNERQEWGRQ KEELLWRVEQ LQKEKSPRRS GSFLCSPRED
950
951
DNRPYPHQGS LHPSRPVSMW PCEDTDSIPF EDRPLSKLKE SDRCSASENL
1000
1001
YLDALSLDDD SEDPPPLRNC LAEEEESRKG NLQRAVSVSC MSEFQRLMDV
1050
1051
SPFLPEKGLP SASSREDVTP PLSPDDLKYI EEFNSKDWDY TSPRAGADRP
1100
1101
PDLWADRTEV GRVGHEATAE PCPDSSWYLT TSVTMTTDTM TSPEHCQKQP
1150
1151
LRTHVLTEQS GVHVLHSPPA IRRVDSIASG GEGRSRVDPE GPFPMSRARG
1200
1201
NLADAKGGHP EPVLNRWPCT PPRHPRDCVE GSLRPLDRPL CPSLGFASPL
1250
1251
NSLDMSRNMS DDMKEVAFSV RNAMCSGPAE PQVRDMACQT NGSRTAGTQT
1300
1301
IQTISVGLQT EALRASGVTS SPHKCLTPKA GGGTTPVSSP SRSLRSRQVA
1350
1351
PAIEKVQAKF ERTCCSPKYG SPKLQRKPPS KADQPNSRTS PGMPQKGFSE
1400
1401
SAWARSTTTR ESPVHTTIND GLSSLFNIID HSPVGVRAGS RSRSAEPRQE
1450
1451
LGPGQETGTS SRGRSPSPLG VGSEMYREDG GESTPVRQDL SAPPGYTLTE
1500
1501
NVARILNKKL LEHALKEERK QATHGSSGLT SDSHPGEAVP AEPGSMEELP
1550
1551
CSALAPSLEP CFSRPERPAN RRLPSRWAPP SPTASQSQSP GDPVSLEERG
1600
1601
EEDPPEEKPH P                                          
1611
 

Show the unformatted sequence.

Checksums:
CRC64:F04C803E9758E739
MD5:96a60805adc7da41da118b958e8052b9

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;