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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D4ACL8_RAT (D4ACL8)

Summary

This is the summary of UniProt entry D4ACL8_RAT (D4ACL8).

Description: Ataxia telangiectasia mutated homolog (Human) (Mapped), isoform CRA_a {ECO:0000313|EMBL:EDL95516.1}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
View Pfam proteome data.
Length: 3064 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam TAN 8 165
disorder n/a 26 27
disorder n/a 41 42
disorder n/a 79 88
low_complexity n/a 430 444
disorder n/a 637 639
disorder n/a 835 856
low_complexity n/a 838 849
low_complexity n/a 933 945
coiled_coil n/a 1618 1641
disorder n/a 1637 1638
low_complexity n/a 1650 1662
disorder n/a 1891 1894
disorder n/a 1975 1996
Pfam FAT 2103 2497
disorder n/a 2582 2605
disorder n/a 2657 2658
Pfam PI3_PI4_kinase 2721 2970
disorder n/a 2723 2727
disorder n/a 2800 2801
disorder n/a 2981 2982
disorder n/a 2984 3002
coiled_coil n/a 3011 3031
Pfam FATC 3033 3064

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D4ACL8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSLALNDLLI CCRQLEHDRA TERRKEVDKF KRLIQDPETV QHLDRHSDSK
50
51
QGKYLNWDAV FRFLQKYIQK ETESLRTAKS NVSASTQTSR QKKMQEISSL
100
101
VRFFIKCANK RAPRLKCQDL LNYVMDTVKD SSNGATYGAD CSNILLKDIL
150
151
SVRKYWCEVS QQQWLELFSL YIRLYLKPSQ DINRVLVARI IHAVTRGCCS
200
201
QTDGLPSKFL DLFSKAIQYA RQEKSSPGLS HILAALNIFL KTLAVNFRKR
250
251
VCEIGDEILP TLLYIWTQHR LNDSLKEVII ELIHLQIYIH HPQGAKAPEE
300
301
GAYESMKWKR ILYNLYDLLV NEISHIGSRG KYSSGSRNIA VKENLIDLMA
350
351
DVCYQLFNAD TRSVEISQSY ATQRESTDYS VPCKRRKIDI GWEVIKDYLQ
400
401
KSQNDFDLVP WLQITTRLIS KYPSSLPNCE LSPLILILYQ LLPQQRRGER
450
451
IPHVLRCLTE VALCQGKKSN LESSQKSDLL KLWIKIWSIT FRGISSEQTQ
500
501
TENFGLLGAI IQGSLVELDR EFWKLFTGSA CKPSSPSVRC LTLALSMCVV
550
551
PDAIKMGTEQ SVCDANRSFS VKESIMRWLL FYQLEGDLED SAEPPPILQS
600
601
NFPHLILEKI LVSLTMKNSK AAMKFFQSAP ECEQHCEDTE EPSFSEAEEL
650
651
FLQTTFDKMD FLTPVKEDTV EKFQSRVGFS VHQNLKESLD HYLLGLSEQL
700
701
LSNYSSEITS SETLVRCSSL LVGVLGCYCY MGVITEDEAY KSELFQKAKS
750
751
LMQCAGESIS LFKNKTNEES RVGSLRSVIH LCTSCLCRHT KHTLNKIASG
800
801
FFLRLLTSKL MNDIADICKS LASCTKKPFD YGEEHSLRDD DDDGDGGDGG
850
851
ESLMETQGSS STDLFSDYSA STVSDANDYG ENQNAVGAAN PLTADWLSRQ
900
901
DHLLLDMLRF LCLSVTACQS RTASFRGADI RRKLLMLLDP STLDLTKSLH
950
951
LHMYLVLLKD LPGKEHLLPM EDVVELLQPL SLVCSLYRRD QDVCKTILSN
1000
1001
VLHIVTNLGQ GSVDTESTRN AQGQFLTVMG AFWHLTKEKK CIFSVRMALV
1050
1051
KCLQTLLEAD PYSKWAILNV KGQDFPVREA FPQFLADGHH HVRMLAAGSI
1100
1101
SRLFQDMRQG DSSRSLKALP LKFQQTSFNS AYMIAEAGIR ELLCDSQNPD
1150
1151
LLDEIYNRKS VLLTVIAVVL HCSPICEKQA LFALCKSVKE NGLEPHLVKK
1200
1201
VLEKVSESFG CRCLEDFMAS HLDYLVLEWL NLQDAKYSLS SFPFTLLNYM
1250
1251
SVEDFYRSCY KILIPHLVIR KHFDEVKSIA NQIQRCWKSL LIDCFPKMLV
1300
1301
HILPYFACEG TGDSSSAQKR ETATEVYDTL KGEDFLGKQI DQVFISNLPE
1350
1351
IVVELLMTLH ETADSDSGQS PDLCDFSGDL DPAPNPPYFP SHVIKATFAY
1400
1401
ISSCHKTKFK SILEILSKIP DSYQKILLAI CEQAAETNNV FKKHRILKIY
1450
1451
HLFVSLLLKD IQSGLGGAWA FVLRDVIYTL IHYINKRSSH FTDVSLRSFS
1500
1501
LCCDLLSRVC RTAVTHCKDA LENHLHVIVG TLIPLVDYQE VQEQVLDLLK
1550
1551
YLVIDNKDNK NLFVTIKLLD PFPDHVVFKD LRLTQQKIKY SGGPFTLLEE
1600
1601
INHFLSVSAY NPLPLTRLEG LKDLRRQLEQ HKDQMLDLVR ASQDNPQDGI
1650
1651
VVKLVVSLLQ LSKMAVNQTG EREVLEAVGR CLGEIGPLDF STIAVQHSKD
1700
1701
TPYTKAYGLP EDRELQWTLI MLTALNNTLV EDSVKIRSAA ATCLKNILAT
1750
1751
KTGHIFWENH KTSADPMLTY LQPFRASRKK FLELPQFVKE DALEGLDDVN
1800
1801
LWVPQSESHD IWIKTLTCAF LDSGGIKSEI LQLLKPMCEV KTDFCQMVLP
1850
1851
YLIHDVLLQD THESWRTLLS THVRGFFTNC FKHSSQASRS ATPANSDSES
1900
1901
ENFLRCCLDK KSQRTMLAVV DYLRRQKRPS SGTAFEDAFW LDLNYLEVAK
1950
1951
VAQSCAAHFT ALLYAEIYSD KKNMDEQEKR SPTFEEGSQG TTISSLSEKS
2000
2001
KEETGISLQD LLLEIYRSIG EPDSLYGCGG GKVLQPLTRI RTYEHEATWE
2050
2051
KALVTYDLET TISSSTRQSG IIQALQNLGL SHILSIYLKG LDHERREWCG
2100
2101
ELQELHYQAA WRNMQWDLCT SANQELEGTS YHESLYNALQ CLRNREFSTF
2150
2151
YDSLRHARVK EVEELSKGSL ESVYSLYPTL SRLQAVGELE NSGELFSRSV
2200
2201
TDRERSEVYL KWQKHSQLLK DSDFSFQEPL MALRTVILEI LVQKEMENSQ
2250
2251
GGCSKDILTK HLVEFSVLAR TFKNTQLPER AIFKIKQYNP AICGISEWHL
2300
2301
EEAQVFWAKK EQSLALSILK QMIKKLDSSF REVCNEAGLK GLHAECLRVC
2350
2351
GNWLAETCLE NPAVIMQTYL EKAVKVAGSY DGDSRELRNG QMKAFLSLAR
2400
2401
FSDTQYQRIE NYMKSSEFEN KQALLKRAKE EVGLIREHKI QTNRYTIKVQ
2450
2451
RELELDECAL RALKEDRKRF LCKAVENYIS CLLSGEEHDL WVFRLCSLWL
2500
2501
ENSGVSEVNG MMKRDGMKIS SYKFLPLMYQ LAARMGTKMT GGLGFHEVLN
2550
2551
NLISRISMDH PHHTLFIILA LANANKDEFL SKPETARRGR ITKNAPKESS
2600
2601
QLDEDRAEAA SRIIHTIRSA RRTMVKDMEA LCDAYIILAN LDASQWRNQR
2650
2651
KGISIPANQP ITKLKNLEDV VVPTMEIKVD PTGEYEKLVT IKSFKTEFRL
2700
2701
AGGLNLPKII DCVGSDGKER RQLVKGRDDL RQDAVMQQVF QMCNMLLQRN
2750
2751
TETRKRKLTI CTYKVVPLSQ RSGVLEWCTG TIPIGEYLVN NEEGAHKRYR
2800
2801
PNDLSANQCQ KKMMEVQKKS FEEKYETFMT ICQNFEPVFR YFCMEKFLDP
2850
2851
AVWFEKRLAY TRSVATSSIV GYILGLGDRH VQNILINEQS AELVHIDLGV
2900
2901
AFEQGKILPT PETVPFRLSR DIVDGMGITG VEGVFRRCCE KTMEVMRSSQ
2950
2951
EALLTIVEVL LYDPLFDWTM NPLKALYLQQ RPEDETDLQS TPSADDQECK
3000
3001
RSLSDTDQSF NKVAERVLMR LQEKLKGVEE GTVLSVGGQV NLLIQQAMDP
3050
3051
KNLSRLFPGW KAWV                                       
3064
 

Show the unformatted sequence.

Checksums:
CRC64:A9CF0EA4F19E65F0
MD5:6aee272f3572fa9d6e58e7ffbd8f1843

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.