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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: D4AEK9_RAT (D4AEK9)

Summary

This is the summary of UniProt entry D4AEK9_RAT (D4AEK9).

Description: Coiled-coil domain-containing 6 {ECO:0000313|Ensembl:ENSRNOP00000033185}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 470 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 32
low_complexity n/a 2 16
low_complexity n/a 22 41
Pfam DUF2046 25 330
disorder n/a 35 37
coiled_coil n/a 49 97
disorder n/a 88 93
coiled_coil n/a 113 133
coiled_coil n/a 135 205
low_complexity n/a 144 163
disorder n/a 149 150
disorder n/a 154 156
coiled_coil n/a 207 227
disorder n/a 222 250
disorder n/a 252 253
coiled_coil n/a 255 318
disorder n/a 256 257
disorder n/a 268 272
disorder n/a 275 304
disorder n/a 306 470
low_complexity n/a 315 327
low_complexity n/a 344 361
low_complexity n/a 404 413
low_complexity n/a 419 450
low_complexity n/a 443 461

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession D4AEK9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MADSASESDT DAAGGGPAAM QSSCSATSGG SGGGGGGKSG GIVISPFRLE
50
51
ELTNRLASLQ QENKVLKIEL ETYKLKCKAL QEENRDLRKA SVTIQARAEQ
100
101
EEEFISNTLF KKIQALQKEK ETLAVNYEKE EEFLTNELSR KLMQLQHEKA
150
151
ELEQHLEQEQ EFQVNKLMKK IKKLENDTIS KQLTLEQLRR EKIDLENTLE
200
201
QEQEALVNRL WKRMDKLEAE KRILQEKLDQ PVSAPPSPRD ISMEIDSPEN
250
251
MMRHIRFLKN EVERLKKQLR AAQLQHSEKM AQYLEEERHM REENLRLQRK
300
301
LQREMERREA LCRQLSESES SLEMDDERYF NEMSAQGLRP RTVSSPIPYT
350
351
PSPSSSRPIS PGLSYASHTV GFTPPTSLTR AGTSYYNSPG LHVQHMGASH
400
401
GITRPSPRRS SSPDKFKRPT PPPSPNTQSP VQPPPPPPPP PMQPAVPSAA
450
451
TTTQPAPSQA QHPVHPSSQP                                 
470
 

Show the unformatted sequence.

Checksums:
CRC64:0263458DDB2F8124
MD5:429dde34752e1b093571f91566005606

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;