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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E7EZ05_DANRE (E7EZ05)

Summary

This is the summary of UniProt entry E7EZ05_DANRE (E7EZ05).

Description: Oxoglutarate dehydrogenase (succinyl-transferring) {ECO:0000256|ARBA:ARBA00012280}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1023 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 25 26
Pfam 2-oxogl_dehyd_N 51 91
Pfam E1_dh 257 583
disorder n/a 452 454
disorder n/a 460 461
coiled_coil n/a 553 573
disorder n/a 605 610
Pfam Transket_pyr 650 866
disorder n/a 790 791
disorder n/a 795 797
Pfam OxoGdeHyase_C 869 1014

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E7EZ05. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MHRLRTCAAR LRPLTASQNA ASFSQHRPAV VHGARRTFQP IRNYTAPVTA
50
51
EPFLNGTSSN YLEEMYYAWL EDPKSVHKSW DIFFRNANAG VAPGSAYQSV
100
101
PPMGLSGLSQ SQALIGAQPN VEKLVEDHLA VQSLIRAYQI RGHHVAQLDP
150
151
LGILDADLDS CVPADIITSS DKLGFYGLEE TDLDKVFRLP TTTFIGGSET
200
201
ALPLREIIHR LEMAYCQHIG VEFMFINDLE QCQWIRQKFE KPGVMQFTLD
250
251
EKRTLLARMV RSTRFEEFLQ RKWSSEKRFG LEGCESLIPA LKTIIDKSSE
300
301
NGVENVIMGM PHRGRLNVLA NVIRKELEQI FCQFDSKLEA ADEGSGDVKY
350
351
HLGMYHRRIN RVTERQITLS LVANPSHLEA VDPVVQGKTK AEQFYCGDTD
400
401
GNRVMSILLH GDAAFAGQGI VYETFHLSDL PSYTTHGTIH VVANNQIGFT
450
451
TDPRMARSSP YPTDVARVVN APIFHVNADD PEAVMYVCNV AAEWRATFHK
500
501
DVVVDLVSYR RNGHNEMDEP MFTQPLMYKQ IKKQKPVLQK YAEKLIAEGA
550
551
VTRQEYEEEI SKYDKICEEA YNRSKDEKIM HIKHWLDSPW PGFFTLDGQP
600
601
KTMSCPSTGL SEETLAHIGQ TASSVPVEDF TIHGGLSRIL KSRSLMVQNR
650
651
SVDWALGEYM AFGSLLKEGI HVRLSGQDVE RGTFSHRHHV LHDQNVDKRT
700
701
CIPMNYMDPN QAPYTVCNSS LSEYGVLGFE LGFAMASPNA LVLWEAQFGD
750
751
FHNTAQCIID QFICPGQAKW VRQNGIVLLL PHGMEGMGPE HSSARPERFL
800
801
QMCNDDPDVF PKITEDFAVR QLYDCNWIVV NCSTPANYFH VLRRQILLPF
850
851
RKPLIIFTPK SLLRHPEAKS SFEEMLPGTH FSRLIPEQGS ASQSAAGVQH
900
901
LIFCTGKVFY DLQRERKSRG LEERVAISRI EQLSPFPFDL VKAEAEKYPH
950
951
AHLLWCQEEH KNQGYYDYVK PRISTTLNNT RPVWYVGRDP AAAPATGNKK
1000
1001
AHLLELQRFL DTAFNLEAFQ SAS                             
1023
 

Show the unformatted sequence.

Checksums:
CRC64:5BE8016FD68A00F0
MD5:343a779f1bc5ee4965404541d03d3feb

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;