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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E7F114_DANRE (E7F114)

Summary

This is the summary of UniProt entry E7F114_DANRE (E7F114).

Description: SEC31 homolog B, COPII coat complex component {ECO:0000313|Ensembl:ENSDARP00000008006}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1171 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
low_complexity n/a 46 57
disorder n/a 158 163
disorder n/a 165 167
disorder n/a 169 170
disorder n/a 343 352
disorder n/a 354 357
disorder n/a 359 366
disorder n/a 375 376
low_complexity n/a 380 387
disorder n/a 408 429
low_complexity n/a 408 426
disorder n/a 431 432
disorder n/a 460 461
disorder n/a 523 525
disorder n/a 534 542
disorder n/a 551 557
disorder n/a 565 568
Pfam Sec16_C 579 776
coiled_coil n/a 723 743
disorder n/a 786 1062
low_complexity n/a 802 814
low_complexity n/a 812 826
low_complexity n/a 863 889
low_complexity n/a 890 925
low_complexity n/a 959 973
low_complexity n/a 980 985
disorder n/a 1064 1065
disorder n/a 1088 1101
coiled_coil n/a 1091 1114

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E7F114. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRVKEILRTA TQAWSPARQH PAYLALGTAA QQLDASFNTS SALEIFDMDF
50
51
SDTSMDMKLR GTLATSNRFH SLIWVAFGMD VQPSSGRLIG GSENGSVTVF
100
101
NPDVILTAGE DAVIGQSNKH TGPVRALDFN RFQSNLIASG ANDSEIYIWD
150
151
LNNFSNPMTP GTKSQPAEDV SVVAWNSQVQ HILASANPSG KAVVWDLRKN
200
201
EPIIKISDHS NRMHCSGMLW HPDVATQLVL ASEDDRLPVI QMWDLRFATS
250
251
PLKVLENHTR GILSISWSQA DPELLLSSGK DNRILCWNPN TGEVIYELPT
300
301
ANQWCFDVQW CPRNPALLSA ASFDGRISVY SVMGGRLQQQ QHSTVDQISA
350
351
SFDTNDPFGM GQTLPPLQVP QAAVETTIIP PLKKPPKWVR RPVGASFAFG
400
401
GKLVTFENPN VAPPQQQQPA NPLPRQVHVS QVTTETEFLQ RSTELQMTLQ
450
451
SGSFSSFCHS KIQSAPTDAE QDIWRFLMVN FEDEARVKFL RLLGFSKDEL
500
501
QRKISACLGR KLQPNGLDVN DLAEKMQTLS DQRADECAGA ADGLPGRESP
550
551
ADFFSQLPKK EKDKQPFQIP VSSDTDGLIS QALLVGNFEG AVDLCLNDGR
600
601
FAEAILLSIS GGEELLKKTQ QRYLQRQTNS ISMLISSVVT QNWRDIVQSC
650
651
ELDNWKEALA ALLTYANPEE FASLCDTLGS RLEAGGSEKL CLQACLCFIC
700
701
SGNIERLVDC WTLQRDCSSP LALEDLVEKV MILRKSIERL RNIEVCVRSS
750
751
ALTQKLIQYS SILASQGSLS AALNYLPSDS DQAAVRMLRD RLSHAKGEIQ
800
801
QKPSAPAGGA KPAPNTHTPA AHTTAPYPSS GAPQMPRLFS PQTGPEPPAG
850
851
ATTHTPRPAY TQHPATAPGF HPFPPAAPQG APGGFFTPQM PSSSLAGPSM
900
901
PPSSPPGPMM PAGVPMMMPT PPAPGFLSPT SLPGGPRFPG SAHTQGPAPP
950
951
PTGAYPSLGA AGYPQGGPGA PAAKSFSGAP VPPPPSGAQD GWNDPPAVRA
1000
1001
GQRKKKLPEN YTPPAPITAP VMGFPAEAPV LQDRVQVPPG APQEPSIQSI
1050
1051
QQLPAERVEQ KEIPAEHMIL KTTFSSLVQR CQLAAADPQT KRKLDDASKR
1100
1101
LENLYDKLRD QSLSPSILGG LHEISRCVSA RSYVQGLEVH TQVVSSSNFS
1150
1151
EISAFMPVLK VLMTIANKLA V                               
1171
 

Show the unformatted sequence.

Checksums:
CRC64:7906FE3F520F0C0D
MD5:52325e421f0707d976060dd953ed148e

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;