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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E7FEC3_DANRE (E7FEC3)

Summary

This is the summary of UniProt entry E7FEC3_DANRE (E7FEC3).

Description: Shisa family member 2b {ECO:0000313|Ensembl:ENSDARP00000105651}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 294 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 27
low_complexity n/a 11 20
Pfam Shisa 27 212
disorder n/a 79 96
transmembrane n/a 104 129
low_complexity n/a 111 127
disorder n/a 141 150
low_complexity n/a 141 152
disorder n/a 157 193
low_complexity n/a 162 203
disorder n/a 258 259
disorder n/a 262 271
disorder n/a 275 286
disorder n/a 288 294

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E7FEC3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRGCTGFPMA VTVVLTLLTV MNVKASGEYC HGWHDAQGVW KDGFQCPERF
50
51
DTPDAIICCG KCELRYCCSS TEARLDQGTC DNDKQTQETN TGSKDDKNSG
100
101
AVPIYVPFLI VGSVFVAFVL VGSVVAVCCC RCLRPKQEPT SGGGSGGASS
150
151
SARVLETIPM MASTGTSRGS SSRQSSTATS SSSSAPPAAP RPAPAPLLRA
200
201
QASCCLPPDA SVYVNMPTNF SVLNCQQATQ ILPHQGQFLH PQYIGFAHPV
250
251
APAAAFLDPT QAGYRPLQSP FPPPTSVASV ASITGDHKHP PVTM      
294
 

Show the unformatted sequence.

Checksums:
CRC64:507E08273B73632E
MD5:c1ad75a3895e893a2ca7ff9ce0f3de2b

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;