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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E9AH43_LEIIN (E9AH43)

Summary

This is the summary of UniProt entry E9AH43_LEIIN (E9AH43).

Description: Fumarate hydratase {ECO:0000256|ARBA:ARBA00012921}
Source organism: Leishmania infantum (NCBI taxonomy ID 5671)
Length: 549 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Fumerase 57 337
Pfam Fumerase_C 342 549
disorder n/a 356 357
disorder n/a 381 387
disorder n/a 412 419
disorder n/a 442 449

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E9AH43. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLRRVAPLLA EFNFVPLVSK VSHKETKYRL LTKDYVSVVQ PGAGLPEMLR
50
51
VDPAALTLLS STAFDDVEHL LRSSHLMCLR KIFDDPEASD NDRFVALQLL
100
101
KNANISSARL LPGCQDTGTA IIAGYRGDQV FVPGNDEEAL SRGVYDIFQK
150
151
RNFRYSQNVP LSMYDEKNTG TNLPAQIDLY ASKGMEYSFM FVAKGGGSAN
200
201
KSFLLQESKS VLNPKSLRKF LKEKLAMFGT SACPPYHVAV VIGGTSAEMT
250
251
MKVLKYASCH YYDDLITKPD MKTGYTFRDL ELEKEVLEIC QNIGMGAQFG
300
301
GKYYAHDVRV IRMPRHGASC PIGIGVSCSA DRQALGKINK DGVWLEELEM
350
351
EPSQYLPDVK EDQLLKTPAV MVNLNRPMPE VLQELSKHPV RTRLSLTGTI
400
401
IVARDSAHAR MREMLEAGKP LPQYMKEHPV YYAGPAKQPD GLPSGSFGPT
450
451
TAGRMDPFVD LFQSHGGSMV MLAKGNRSKQ VTKACHKYGG FYLGSIGGPA
500
501
AVLAQDAIKK VECLDMKDLG MEAVWKIEVE NFPAFIVVDD KGNDFFEQL 
549
 

Show the unformatted sequence.

Checksums:
CRC64:08C3E8202A6D09BF
MD5:4b581d93f51e7fdab74ff1de7a24c7e6

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;