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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CTRO_RAT (E9PSL7)

Summary

This is the summary of UniProt entry CTRO_RAT (E9PSL7).

Description: Citron rho-interacting kinase {ECO:0000250|UniProtKB:O14578}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 2055 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam Pkinase 97 359
disorder n/a 371 383
disorder n/a 386 391
coiled_coil n/a 457 615
disorder n/a 461 472
disorder n/a 521 525
disorder n/a 534 536
disorder n/a 538 539
disorder n/a 552 553
disorder n/a 605 614
disorder n/a 616 617
disorder n/a 620 624
coiled_coil n/a 623 747
low_complexity n/a 632 646
disorder n/a 648 649
disorder n/a 651 652
disorder n/a 655 663
disorder n/a 665 694
disorder n/a 696 725
disorder n/a 727 743
disorder n/a 745 757
disorder n/a 764 766
coiled_coil n/a 773 793
disorder n/a 777 806
coiled_coil n/a 801 835
disorder n/a 834 846
coiled_coil n/a 857 884
disorder n/a 869 887
disorder n/a 889 890
low_complexity n/a 891 905
disorder n/a 892 893
coiled_coil n/a 892 1083
disorder n/a 895 896
low_complexity n/a 915 932
low_complexity n/a 929 948
disorder n/a 945 968
low_complexity n/a 950 968
disorder n/a 991 992
disorder n/a 995 999
disorder n/a 1008 1011
disorder n/a 1022 1023
disorder n/a 1026 1027
disorder n/a 1039 1051
disorder n/a 1053 1055
disorder n/a 1057 1058
coiled_coil n/a 1095 1122
disorder n/a 1113 1121
coiled_coil n/a 1134 1210
low_complexity n/a 1138 1156
disorder n/a 1159 1160
disorder n/a 1164 1167
disorder n/a 1169 1171
disorder n/a 1176 1177
low_complexity n/a 1182 1203
coiled_coil n/a 1218 1238
disorder n/a 1277 1279
disorder n/a 1282 1284
coiled_coil n/a 1284 1318
disorder n/a 1309 1348
disorder n/a 1351 1383
low_complexity n/a 1353 1364
disorder n/a 1386 1390
Pfam PH 1470 1589
disorder n/a 1472 1477
Pfam CNH 1627 1889
disorder n/a 1932 2055

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E9PSL7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLKFKYGVRN PSEASAPEPI ASRASRLNLF FQGKPPLMTQ QQMSALSREG
50
51
VLDALFVLLE ECSQPALMKI KHVSSFVRKY SDTIAELREL QPSVRDFEVR
100
101
SLVGCGHFAE VQVVREKATG DVYAMKIMKK AALRAQEQVS FFEEERNILS
150
151
QSTSPWIPQL QYAFQDKNNL YLVMEYQPGG DLLSLLNRYE DQLDENMIQF
200
201
YLAELILAVH SVHQMGYVHR DIKPENILID RTGHIKLVDF GSAAKMNSNK
250
251
VDAKLPIGTP DYMAPEVLTV MNEDRRGTYG LDCDWWSVGV VAYEMLYGKT
300
301
PFTEGTSART FNNIMNFQRF LKFPDDPKVS SELLDLIQSL LCVQKERLKF
350
351
EGLCCHPFFA RTDWNNIRNS PPPFVPTLKS DDDTSNFDEP EKNSWVSSSP
400
401
CQLSPSGFSG EELPFVGFSY SKALGYLGRS ESVVSGLDSP AKISSMEKKL
450
451
LIKSKELQDS QDKCHKMEQE MARLHRRVSE VEAVLSQKEV ELKASETQRS
500
501
LLEQDLATYI TECSSLKRSL EQARMEVSQE DDKALQLLHD IREQSRKLQE
550
551
IKEQEYQAQV EEMRLMMNQL EEDLVSARRR SDLYESELRE SRLAAEEFKR
600
601
KANECQHKLM KAKDLGKPEV GECSRLEKIN AEQQLKIQEL QEKLEKAVKA
650
651
STEATELLQN IRQAKERAER ELEKLHNRED SSEGIKKKLV EAEERRHSLE
700
701
NKVKRLETME RRENRLKDDI QTKSEQIQQM ADKILELEEK HREAQVSAQH
750
751
LEVHLKQKEQ HYEEKIKVLD NQIKKDLADK ESLETMMQRH EEEAHEKGKI
800
801
LSEQKAMINA MDSKIRSLEQ RIVELSEANK LAANSSLFTQ RNMKAQEEMI
850
851
SELRQQKFYL ETQAGKLEAQ NRKLEEQLEK ISHQDHSDKN RLLELETRLR
900
901
EVSLEHEEQK LELKRQLTEL QLSLQERESQ LTALQAARAA LESQLRQAKT
950
951
ELEETTAEAE EEIQALTAHR DEIQRKFDAL RNSCTVITDL EEQLNQLTED
1000
1001
NAELNNQNFY LSKQLDEASG ANDEIVQLRS EVDHLRREIT EREMQLTSQK
1050
1051
QTMEALKTTC TMLEEQVMDL EALNDELLEK ERQWEAWRSV LGDEKSQFEC
1100
1101
RVRELQRMLD TEKQSRARAD QRITESRQVV ELAVKEHKAE ILALQQALKE
1150
1151
QKLKAESLSD KLNDLEKKHA MLEMNARSLQ QKLETERELK QRLLEEQAKL
1200
1201
QQQMDLQKNH IFRLTQGLQE ALDRADLLKT ERSDLEYQLE NIQVLYSHEK
1250
1251
VKMEGTISQQ TKLIDFLQAK MDQPAKKKKV PLQYNELKLA LEKEKARCAE
1300
1301
LEEALQKTRI ELRSAREEAA HRKATDHPHP STPATARQQI AMSAIVRSPE
1350
1351
HQPSAMSLLA PPSSRRKEAS TPEEFSRRLK ERMHHNIPHR FNVGLNMRAT
1400
1401
KCAVCLDTVH FGRQASKCLE CQVMCHPKCS TCLPATCGLP AEYATHFTEA
1450
1451
FCRDKVSSPG LQSKEPSSSL HLEGWMKVPR NNKRGQQGWD RKYIVLEGSK
1500
1501
VLIYDNEARE AGQRPVEEFE LCLPDGDVSI HGAVGASELA NTAKADVPYI
1550
1551
LKMESHPHTT CWPGRTLYLL APSFPDKQRW VTALESVVAG GRVSREKAEA
1600
1601
DAKLLGNSLL KLEGDDRLDM NCTLPFSDQV VLVGTEEGLY ALNVLKNSLT
1650
1651
HIPGIGAVFQ IYIIKDLEKL LMIAGEERAL CLVDVKKVKQ SLAQSHLPAQ
1700
1701
PDVSPNIFEA VKGCHLFAAG KIENSLCICA AMPSKVVILR YNDNLSKFCI
1750
1751
RKEIETSEPC SCIHFTNYSI LIGTNKFYEI DMKQYTLEEF LDKNDHSLAP
1800
1801
AVFASSTNSF PVSIVQANST GQREEYLLCF HEFGVFVDSY GRRSRTDDLK
1850
1851
WSRLPLAFAY REPYLFVTHF NSLEVIEIQA RSSLGTPARA YLEIPNPRYL
1900
1901
GPAISSGAIY LASSYQDKLR VICCKGNLVK ESGTEQHRVP STSRSSPNKR
1950
1951
GPPTYNEHIT KRVASSPAPP EGPSHPREPS TPHRYRDREG RTELRRDKSP
2000
2001
GRPLEREKSP GRMLSTRRER SPGRLFEDSS RGRLPAGAVR TPLSQVNKVW
2050
2051
DQSSV                                                 
2055
 

Show the unformatted sequence.

Checksums:
CRC64:237329B7CF7C0596
MD5:88cfd94ca153d10370d43ffdab6a60f5

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;