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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E9PT85_RAT (E9PT85)

Summary

This is the summary of UniProt entry E9PT85_RAT (E9PT85).

Description: ATP-dependent DNA helicase 2 subunit 1 {ECO:0000256|ARBA:ARBA00014630}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 609 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 4 27
low_complexity n/a 11 19
Pfam Ku_N 35 254
disorder n/a 175 185
low_complexity n/a 178 189
Pfam Ku 261 467
Pfam Ku_C 470 555
disorder n/a 534 554
Pfam SAP 571 605
disorder n/a 597 602

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E9PT85. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSEWESYYKT EGEEEEEEEQ SPDTNGEYKY SGRDSLIFLV DASRAMFESQ
50
51
GEDELTPFDM SIQCIQSVYT SKIISSDRDL LAVVFYGTEK DKNSVNFKSI
100
101
YVLQDLDNPG AKRVLELDRF KGQQGKKHFR DTIGHGSDYS LSEVLWVCAN
150
151
LFSDVQFKMS HKRIMLFTNE DDPHGNDSAK ASRARTKASD LRDTGIFLDL
200
201
MHLKKRGGFD VSLFYRDIIS IAEDEDLGVH FEESSKLEDL LRKVRAKETK
250
251
KRVLSRLKFK LGKDVALMVG VYNLVQKANK PFPVRLYRET NEPVKTKTRT
300
301
FNVNTGSLLL PSDTKRSLTF GTRQIVLEKE ETEELKRFDE PGLILMGFKP
350
351
MVMLKNHHYL RPSLFLYPEE SLVNGSSTLF SALLTKCVEK EVIAVCRYTA
400
401
RKNVSPYFVA LVPQEEELDD QNIQVTPAGF QLVFLPYADD KRKVPFTEKV
450
451
MANPEQIDKM KAIVQKLRFT YRSDSFENPV LQQHFRNLEA LALDMMESEQ
500
501
VVDLTLPKVE AIKKRLGSLA DEFKELVYPP GYNPEGKIAK RKADNEGSAS
550
551
KKPKVELSEE ELKDLFAKGT LGKLTVPALR DICKAYGLKS GPKKQELLEA
600
601
LSRHLEKTD                                             
609
 

Show the unformatted sequence.

Checksums:
CRC64:74A1CE43CF0C23B7
MD5:5c399f87f2a5ef918e0d0f8c186c226c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;