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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E9PTW9_RAT (E9PTW9)

Summary

This is the summary of UniProt entry E9PTW9_RAT (E9PTW9).

Description: TLE family member 2, transcriptional corepressor {ECO:0000313|Ensembl:ENSRNOP00000057991}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 696 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 7
Pfam TLE_N 17 133
coiled_coil n/a 25 52
low_complexity n/a 118 129
disorder n/a 124 145
low_complexity n/a 144 171
disorder n/a 171 343
low_complexity n/a 188 209
low_complexity n/a 273 288
low_complexity n/a 343 363
disorder n/a 373 375
disorder n/a 378 380
disorder n/a 387 394
Pfam WD40 401 437
Pfam WD40 494 528
Pfam WD40 532 570

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E9PTW9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MYPQGRHPTP LQSGQPFKFS VLEICDRIKE EFQFLQAQYH SLKLECEKLA
50
51
SEKTEMQRHY VMYYEMSYGL NIEMHKQAEI VKRLSAICAQ MVPFLTQEHQ
100
101
QQVLQAVDRA KQVTVGELNN LLGQQNQLQP LSHAPPVPLT PRPAGLVGAG
150
151
ATGLLALSGA LAAQAQLVAA VKEDRVGVDT EGSRVDRAAS RSSSPSPPES
200
201
LAEEEHPSSR DSNGKQQRAE DKNMSGPYDS EEDKSDYNLV VDEDQPSEPP
250
251
SPATTPCGKA PLCIPARRDL TDSPASLASS LGSPLPRSKD LALNDLSTGT
300
301
PASGSCGPSP PQDSSTPGPS SASHLCQLAT QPAPPTDSIA LRSPLTLSSP
350
351
FTSSFSLGSH STLNGDLSMP GSYVSLHLSP QMQPVPFPSD ALVGTGIPRH
400
401
ARQLHTLAHG EVVCAVTISS STQHVYTGGK GCVKVWDVGQ PGSKTPVAQL
450
451
DCLNRDNYIR SCKLLPDGQS LIVGGEASTL SIWDLAAPTP RIKAELTSSA
500
501
PACYALAISP DAKVCFSCCS DGNIVVWDLQ NQAMVRQFQG HTDGASCIDI
550
551
SDYGTRLWTG GLDNTVRCWD LREGRQLQQH DFSSQIFSLG HCPSQDWLAV
600
601
GMESSHVEVL HVRKPEKYQL RLHESCVLSL KFASCGRWFV STGKDNLLNA
650
651
WRTPYGASIF QSKESSSVLS CDISRNNKYI VTGSGDKKAT VYEVVY    
696
 

Show the unformatted sequence.

Checksums:
CRC64:8219A0D28C8D8579
MD5:d53a3cd8aaf6f4c0c1351a7f6135ce0f

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;