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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E9PU01_RAT (E9PU01)

Summary

This is the summary of UniProt entry E9PU01_RAT (E9PU01).

Description: DNA helicase {ECO:0000256|ARBA:ARBA00012551}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 1921 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 153
low_complexity n/a 29 45
low_complexity n/a 49 69
low_complexity n/a 81 91
low_complexity n/a 107 144
Pfam CHDNT 157 210
disorder n/a 205 217
low_complexity n/a 217 240
disorder n/a 232 291
low_complexity n/a 234 249
low_complexity n/a 271 291
disorder n/a 293 354
low_complexity n/a 296 303
low_complexity n/a 296 303
low_complexity n/a 301 318
low_complexity n/a 321 347
Pfam PHD 365 410
disorder n/a 418 435
low_complexity n/a 424 443
Pfam PHD 444 489
disorder n/a 502 531
low_complexity n/a 506 527
disorder n/a 571 596
Pfam Chromo 615 667
low_complexity n/a 675 694
disorder n/a 676 678
disorder n/a 682 691
disorder n/a 696 707
Pfam SNF2-rel_dom 721 1018
low_complexity n/a 898 912
Pfam Helicase_C 1043 1157
low_complexity n/a 1044 1056
disorder n/a 1222 1239
disorder n/a 1250 1267
disorder n/a 1281 1299
coiled_coil n/a 1281 1301
low_complexity n/a 1282 1300
Pfam DUF1087 1285 1345
disorder n/a 1306 1314
disorder n/a 1318 1394
low_complexity n/a 1342 1360
Pfam CHDII_SANT-like 1373 1514
disorder n/a 1435 1437
disorder n/a 1466 1479
disorder n/a 1482 1483
disorder n/a 1505 1698
low_complexity n/a 1526 1540
low_complexity n/a 1558 1577
low_complexity n/a 1588 1611
low_complexity n/a 1605 1639
coiled_coil n/a 1665 1686
low_complexity n/a 1669 1680
Pfam CHDCT2 1734 1880
disorder n/a 1842 1851
coiled_coil n/a 1856 1876
disorder n/a 1901 1921
low_complexity n/a 1909 1921

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E9PU01. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASGLGSPSP CSAGSEEEDM DALLNNSLPP PHPENEDDPE EDLSEAETPK
50
51
LKKKKKPKKP RDPKIPKSKR QKKELGDSSG EGPEFVEEDE EAALRSDSEG
100
101
SDYTPGKKKK KKLGPKKEKK SKSKRKEEEE EEDDDDDSKE PKSSAQLLED
150
151
WGMEDIDHVF SEEDYRTLTN YKAFSQFVRP LIAAKNPKIA VSKMMMVLGA
200
201
KWREFSTNNP FKGSSGASVA AAAAAAVAVV ESMVTATEVA PPPPPVEVPI
250
251
RKAKTKEGKG PNARRKPKGS PRVPDAKKPK PKKVAPLKIK LGGFGSKRKR
300
301
SSSEDDDLDV ESDFDDASIN SYSVSDGSTS RSSRSRKKLR TAKKKKKGEE
350
351
EVTAVDGYET DHQDYCEVCQ QGGEIILCDT CPRAYHMVCL DPDMEKAPEG
400
401
KWSCPHCEKE GIQWEAKEDN SEGEEILEEV GGDPEEEDDH HMEFCRVCKD
450
451
GGELLCCDTC PSSYHIHCLN PPLPEIPNGE WLCPRCTCPA LKGKVQKILI
500
501
WKWGQPPSPT PVPRPPDADP NTPSPKPLEG RPERQFFVKW QGMSYWHCSW
550
551
VSELQLELHC QVMFRNYQRK NDMDEPPSGD FGGDEEKSRK RKNKDPKFAE
600
601
MEERFYRYGI KPEWMMIHRI LNHSVDKKGH VHYLIKWRDL PYDQASWESE
650
651
DVEIQDYDLF KQSYWNHREL MRGEEGRPGK KLKKVKLRKL ERPPETPTVD
700
701
PTVKYERQPE YLDATGGTLH PYQMEGLNWL RFSWAQGTDT ILADEMGLGK
750
751
TVQTAVFLYS LYKEGHSKGP FLVSAPLSTI INWEREFEMW APDMYVVTYV
800
801
GDKDSRAIIR ENEFSFEDNA IRGGKKASRM KKEASVKFHV LLTSYELITI
850
851
DMAILGSIDW ACLIVDEAHR LKNNQSKFFR VLNGYSLQHK LLLTGTPLQN
900
901
NLEELFHLLN FLTPERFHNL EGFLEEFADI AKEDQIKKLH DMLGPHMLRR
950
951
LKADVFKNMP SKTELIVRVE LSPMQKKYYK YILTRNFEAL NARGGGNQVS
1000
1001
LLNVVMDLKK CCNHPYLFPV AAMEAPKMPN GMYDGSALIR ASGKLLLLQK
1050
1051
MLKNLKEGGH RVLIFSQMTK MLDLLEDFLE HEGYKYERID GGITGNMRQE
1100
1101
AIDRFNAPGA QQFCFLLSTR AGGLGINLAT ADTVIIYDSD WNPHNDIQAF
1150
1151
SRAHRIGQNK KVMIYRFVTR ASVEERITQV AKKKMMLTHL VVRPGLGSKT
1200
1201
GSMSKQELDD ILKFGTEELF KDEATDGGGD NKEGEDSSVI HYDDKAIERL
1250
1251
LDRNQDETED TELQGMNEYL SSFKVAQYVV REEEMGEEEE VEREIIKQEE
1300
1301
SVDPDYWEKL LRHHYEQQQE DLARNLGKGK RIRKQVNYND GSQEDRDWQD
1350
1351
DQSDNQSDYS VASEEGDEDF DERSEAPRRP SRKGLRNDKD KPLPPLLARV
1400
1401
GGNIEVLGFN ARQRKAFLNA IMRYGMPPQD AFTTQWLVRD LRGKSEKEFK
1450
1451
AYVSLFMRHL CEPGADGAET FADGVPREGL SRQHVLTRIG VMSLIRKKVQ
1500
1501
EFEHVNGRWS MPELAEVEEN KKMSQPGSPS PKTPTPSTPG DTQPNTPAPV
1550
1551
PPAEDGIKIE ENSLKEEEST EGEKEVKPTA PEVTVECAQP PAPAPAPASG
1600
1601
PGPTPGPAPA PEDDKAPAEP PEGEEKVEKA EVKERAEEPM ETESKGTTEV
1650
1651
EKAEEKSAVD LTPIVVEDKE EKKEEEEKKE VLLQNGETPK DLSDEKQKKN
1700
1701
LKQRFMFNIA DGGFTELHSL WQNEERAATV TKKTYEIWHR RHDYWLLAGI
1750
1751
INHGYARWQD IQNDPRYAIL NEPFKGEMNR GNFLEIKNKF LARRFKLLEQ
1800
1801
ALVIEEQLRR AAYLNMSEDP SHPSMALNTR FAEVECLAES HQHLSKESMA
1850
1851
GNKPANAVLH KVLKQLEELL SDMKADVTRL PATIARIPPV AVRLQMSERN
1900
1901
ILSRLANRAP EPPPQQVAQQ Q                               
1921
 

Show the unformatted sequence.

Checksums:
CRC64:C6B52D00127E7064
MD5:8b2deacbe3821d6519e2b1fc90d504fd

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;