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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E9PVZ3_MOUSE (E9PVZ3)

Summary

This is the summary of UniProt entry E9PVZ3_MOUSE (E9PVZ3).

Description: Coiled-coil domain-containing 144B {ECO:0000313|Ensembl:ENSMUSP00000132995}
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 520 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 16
coiled_coil n/a 66 93
coiled_coil n/a 122 163
disorder n/a 132 136
disorder n/a 203 222
coiled_coil n/a 238 258
disorder n/a 242 243
disorder n/a 245 248
coiled_coil n/a 296 323
low_complexity n/a 302 314
coiled_coil n/a 356 376
Pfam DUF3496 382 485
coiled_coil n/a 382 402
coiled_coil n/a 424 444
disorder n/a 463 465

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E9PVZ3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEDVGDLTQS SETASEYGRP PCPNYEAILR LIERLSLECK DSGSLLKIQN
50
51
AIHSYKRLIQ LKTGHCKVLL EKLQTVENEV NGLRKKLADA AREQLQQGQE
100
101
LCNVRFTLKQ EEEKRKNVVW VYDKMKEQLR EKEDQYNKEV KMKQKLEIRV
150
151
RELDMDLKTV RHNLNTVLEE RNCIERQLFQ EQNTRIIQDE ILANHLHKQK
200
201
ELKMAQEKIS SQLQEAPDQH TQCTEKMRDC IQKLGLENHK LKETARKQAE
250
251
KIEQLKKNLL SGVLSDDLTE KLESASAKYL HLYEQNQLLR RELLSMRTIQ
300
301
RKCEKLKKHK KKLEQEVVSL RSHMKRNMIE CGQIEQYKWE IEEKTKQELV
350
351
GKLKQVNLFL QTQAAYEDKL EKLRQKQNAS VRTQMELRIK DLESEFSKMK
400
401
SQVDCNQIEM ENYKQLYLAE VKIRKSLSNK LSKTDERLAE VKTKLLLERK
450
451
QYRASQYSMV DTRPALEPTC PRDSNKFFIP RSFSGEIMLP KSDLWHSIET
500
501
MENCKTKASD QLCICLSSLH                                 
520
 

Show the unformatted sequence.

Checksums:
CRC64:191F1C251B756E42
MD5:fed55a7e2b50b0e681f9fc997d720a54

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;