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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E9Q368_MOUSE (E9Q368)

Summary

This is the summary of UniProt entry E9Q368_MOUSE (E9Q368).

Description: TAR RNA-binding protein 1 {ECO:0000313|Ensembl:ENSMUSP00000129815}
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1579 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 17 31
low_complexity n/a 47 57
disorder n/a 68 69
low_complexity n/a 77 97
low_complexity n/a 112 127
disorder n/a 184 185
low_complexity n/a 195 207
disorder n/a 756 758
disorder n/a 1369 1376
disorder n/a 1378 1380
Pfam SpoU_methylase 1421 1564

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E9Q368. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MERVLADALL TQSREPGELL GALCGGEASA ERAETLRLVL QRLEERGAGA
50
51
GALAKAAHEV ARDHLVPLLH ASQGGGPARP RVLRAASAAL RSCARLAGPE
100
101
LAVTLAEEAL RELPSAPAVE LLAAVAPCLR APEDAPLLRR LGRASVELAL
150
151
AGDAPPAVGA RLLPALAQSA EPALRAAWDA LSSAGPGAEG STGPELLVLS
200
201
ALAEKLLTNH ERHGDLDARL CGRFWRTVQA GLGRAQDGLT RKRARYLLQR
250
251
AVQVSAELAV DCSCSPQDTK GPSLFWWSEK RKDELLKFWE NYILIMEILE
300
301
GNQIHVIKPA LPKLNRLFEC AVSEENGCWL FHPSWHTCIY KRMFESENKI
350
351
LAKEGVIHFL ELYDVKSLPY SPELSEFITG PLMDALSESC LYSRSPGQPL
400
401
GSDSPLGLKL QKFLVTYTSL LPEETKSCFL LKLIQRMADR HWCAVPVLFL
450
451
SRALASIPSC KALGGEGLLA LRDVLQRTMI THQVLLRGAA QCYLLQTAMR
500
501
LVDVEKVSLS DISAFLLSLR QEESLGRGTV LWTELCDWLR VNERYFKQSS
550
551
LGGSDGQEAS LNAYVKNLVQ EFVKSPGWEK ESSFMPDWLD ARLTALMVLL
600
601
AVDVEGLKTK FREKQRTQNV LRIFLDPLLD ALGKLGTNAY MPLLRTDRCL
650
651
QLLVRLLHSC VPRRPGAQDD EVSTALQGSI MSASESVSQF VLRRLTMNEL
700
701
QDVADLDRCQ LYLTVLSELM SLQVKLGWKA GNPISRVLSP LKNACVRHLQ
750
751
EAEDRQEPTL SHQVQRVVSM AALAALCEAV DQYPVLQPDS PNAEPVDRFL
800
801
SALPLNHVLQ KPRSEEQSIG VCPLENGSVF EESLSSKGWG KVVAQYLHDQ
850
851
WVCLSFLLRK HHHLIPSTES DVLEGFLPTA ETPVQALQAA LDVLTVLPAG
900
901
RILPVFRCME VLVPKLLTSE ETLCIESFDV AWKIISSLSN TQLTFWPNLK
950
951
AFVHFVFDHE ILTIAAKLKG QVYFKIKEIM CKMIEMSSIK SGVFNILIRH
1000
1001
CCQSWLVAAS GVSQGSFSSA KDYSELVLEA CVFGTVFRRD QRLIQDVQTF
1050
1051
IENLGQGCAA NVIIENAKRE DYYVRICAIK FLCLLDGSDV SHKLFLEALA
1100
1101
IKLLDKDESA SRSRTRYHEN SLQHRVKNRV WQTLLVLFPA FDQNFLHGII
1150
1151
DKVFHAGFTN NQASIKYFIE WLIILILHKF PEFLPKFWAC FSYGEEKIKA
1200
1201
SICTFLSVLS HLDIIVQNIP EKKLVLKQAL TVALQWCLSH NFSVRLYALV
1250
1251
ALKKAWHLCK TLQFEECGAW TAVIECSLSQ AESMHGAGNA RKNWQRIQDH
1300
1301
FFFSTFHPLK DYCLETIFYT LPRLSGVTGE EWIALDKFAN FTDIPSNAGS
1350
1351
QWYLSGTALG ELSPGDWSQQ DQGSTLGEAD SQSEWADVQK KIIPWGQSAL
1400
1401
ESDLELEFQD RAAKLGKSIS RLIVVASLID KPTNLGGLCR TCEVFGAAVL
1450
1451
VVGSLQCVSD RQFQHLSVSA EQWLPLVEVR PSQLMNYLQQ KKAEGYTVIG
1500
1501
VEQTAQSSDL AQYRFPEKSL LLLGNEREGI PANLIQQLDV CVEIPQQGII
1550
1551
RSLNVHVSGA LLIWEYTRQQ LLGCAEPPS                       
1579
 

Show the unformatted sequence.

Checksums:
CRC64:3950E152817C2954
MD5:4b86920b39bc928df99637b385231b98

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;