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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: E9Q7L0_MOUSE (E9Q7L0)

Summary

This is the summary of UniProt entry E9Q7L0_MOUSE (E9Q7L0).

Description: Oxoglutarate dehydrogenase (succinyl-transferring) {ECO:0000256|ARBA:ARBA00012280}
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1029 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 34 44
Pfam 2-oxogl_dehyd_N 44 81
disorder n/a 85 89
Pfam E1_dh 262 588
low_complexity n/a 439 450
disorder n/a 458 459
disorder n/a 465 466
coiled_coil n/a 558 578
disorder n/a 610 614
Pfam Transket_pyr 655 871
disorder n/a 795 805
Pfam OxoGdeHyase_C 874 1019
disorder n/a 891 894

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E9Q7L0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSQLRLLPFR LGPRATKLLA TRAIPVFSGC RRSSGPPTTI PRSRSGVSSS
50
51
YVEEMYFAWL ENPQSVHKSW DSFFQRASKE ASVGPAQPQL PAVLQESRTS
100
101
VSSCTKTSKL VEDHLAVQSL IRAYQIRGHH VAQLDPLGIL DADLDSFVPS
150
151
DLITTIDKLG KSWDPSLLSF YAALASFPAF YDLQEADLDK EFRLPTTTFI
200
201
GGPENTLSLR EIIRRLESTY CQHIGLEFMF INDVEQCQWI RQKFETPGVM
250
251
QFSVEEKRTL LARLVRSMRF EDFLARKWSS EKRFGLEGCE VMIPALKTII
300
301
DKSSEMGIEN VILGMPHRGR LNVLANVIRK DLEQIFCQFD PKLEAADEGS
350
351
GDVKYHLGMY HERINRVTNR NITLSLVANP SHLEAVDPVV QGKTKAEQFY
400
401
RGDAQGRKVM SILVHGDAAF AGQGVVYETF HLSDLPSYTT NGTVHVVVNN
450
451
QIGFTTDPRM ARSSPYPTDV ARVVNAPIFH VNADDPEAVI YVCSVAAEWR
500
501
NTFNKDVVVD LVCYRRRGHN EMDEPMFTQP LMYKQIHKQV PVLKKYADKL
550
551
IAEGTVTLQE FEEEIAKYDR ICEEAYGRSK DKKILHIKHW LDSPWPGFFN
600
601
VDGEPKSMTC PTTGIPEEML THIGSVASSV PLEDFKIHTG LSRILRGRAD
650
651
MTKKRTVDWA LAEYMAFGSL LKEGIHVRLS GQDVERGTFS HRHHVLHDQE
700
701
VDRRTCVPMN HLWPDQAPYT VCNSSLSEYG VLGFELGYAM ASPNALVLWE
750
751
AQFGDFHNTA QCIIDQFIST GQAKWVRHNG IVLLLPHGME GMGPEHSSAR
800
801
PERFLQMSND DSDAYPVFTE DFEVSQLYDC NWIVVNCSTP ASYFHVLRRQ
850
851
ILLPFRKPLI VFTPKSLLRH PDAKSSFDQM VSGTSFQRLI PEDGPAAHSP
900
901
EQVQRLIFCT GKVYYDLVKE RSSQGLEQQV AITRLEQISP FPFDLIMREA
950
951
EKYSGAELVW CQEEHKNMGY YDYISPRFMT LLGHSRPIWY VGRDPAAAPA
1000
1001
TGNKNAHLVS LRRFLDTAFN LKAFEGKTF                       
1029
 

Show the unformatted sequence.

Checksums:
CRC64:773E485DF51BDF6E
MD5:a7f8b6475cf8849bce1083a1cb401701

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;