Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1LPP8_RAT (F1LPP8)

Summary

This is the summary of UniProt entry F1LPP8_RAT (F1LPP8).

Description: DNA helicase {ECO:0000256|ARBA:ARBA00012551}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 1835 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam CHDNT 1 33
disorder n/a 1 9
sig_p n/a 1 58
disorder n/a 11 13
disorder n/a 15 18
disorder n/a 25 26
low_complexity n/a 37 63
disorder n/a 58 130
low_complexity n/a 65 88
low_complexity n/a 125 138
disorder n/a 139 183
low_complexity n/a 178 194
disorder n/a 190 195
disorder n/a 199 203
Pfam PHD 214 259
coiled_coil n/a 258 285
disorder n/a 264 282
low_complexity n/a 264 285
Pfam PHD 290 335
low_complexity n/a 352 362
disorder n/a 355 374
low_complexity n/a 357 371
disorder n/a 420 443
Pfam Chromo 463 515
disorder n/a 496 501
disorder n/a 516 518
disorder n/a 524 556
low_complexity n/a 529 535
Pfam SNF2-rel_dom 571 867
low_complexity n/a 747 761
low_complexity n/a 887 905
Pfam Helicase_C 892 1006
low_complexity n/a 1070 1083
disorder n/a 1071 1084
disorder n/a 1095 1111
coiled_coil n/a 1124 1144
low_complexity n/a 1126 1143
Pfam DUF1087 1127 1188
disorder n/a 1135 1138
disorder n/a 1150 1154
disorder n/a 1156 1157
disorder n/a 1161 1173
disorder n/a 1176 1229
low_complexity n/a 1200 1214
Pfam CHDII_SANT-like 1208 1349
disorder n/a 1270 1272
disorder n/a 1300 1315
disorder n/a 1317 1318
disorder n/a 1340 1537
low_complexity n/a 1351 1382
low_complexity n/a 1411 1420
low_complexity n/a 1454 1465
Pfam CHDCT2 1569 1715
disorder n/a 1682 1685
coiled_coil n/a 1691 1711
disorder n/a 1736 1759
low_complexity n/a 1749 1768
low_complexity n/a 1765 1781
disorder n/a 1789 1790
disorder n/a 1805 1806
disorder n/a 1814 1818
disorder n/a 1825 1826
disorder n/a 1831 1832

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1LPP8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRPLIAKKNP KIPMSKMMTI LGAKWREFSA NNPFKGSAAA VAAAAAAAAA
50
51
AVAEQVSAAV SSATPIAPSG PPPALPPPPA PEIQPPPIRR AKTKEGKGPG
100
101
HKRRGKSARA PDGRKKLRGK KMAPLKIKLG LLGGRRRKAG SCVFQGDEGP
150
151
EPEAEESDLD SGSVHSASGR PDGPVRAKKL KRGRPGRKKK KVLGCPTVTG
200
201
EEEVDGYETD HQDYCEVCQQ GGEIILCDTC PRAYHLVCLD PELDRAPEGK
250
251
WSCPHCEKEG VQWEAKEEEE DYEEEGEEGE KEEEDDHMEY CRVCKDGGEL
300
301
LCCDACISSY HIHCLNPPLP DIPNGEWLCP RCTCPVLKGR VQKILHWRWG
350
351
EPPVAVPAPQ QADGDPDAPP PRVLQGRSER EFFVKWVGLS YWHCSWAKEL
400
401
QLEIFHLVMY RNYQRKNDMD EPPPLDYGSG EDDGKSDKRK VKDPHYAEME
450
451
EKYYRFGIKP EWMTVHRIIN HSMDKKGNYH YLVKWKDLPY DQSTWEEDEM
500
501
NIPEYDDHKQ SYWRHRELIM GEDPAQPRKY KKKKKEIQGD GPPSSPTNDP
550
551
TVKYETQPRF ITATGGTLHM YQLEGLNWLR FSWAQGTDTI LADEMGLGKT
600
601
IQTIVFLYSL YKEGHTKGPF LVSAPLSTII NWEREFQMWA PKFYVVTYTG
650
651
DKDSRAIIRE NEFSFEDNAI KGGKKAFKMK REAQVKFHVL LTSYELITID
700
701
QAALGSIRWA CLVVDEAHRL KNNQSKFFRV LNGYKIDHKL LLTGTPLQNN
750
751
LEELFHLLNF LTPERFNNLE GFLEEFADIS KEDQIKKLHD LLGPHMLRRL
800
801
KADVFKNMPA KTELIVRVEL SPMQKKYYKY ILTRNFEALN SRGGGNQVSL
850
851
LNIMMDLKKC CNHPYLFPVA AMESPKLPSG AYEGGALIKS SGKLLLLQKM
900
901
LRKLKEQGHR VLIFSQMTKM LDLLEDFLDY EGYKYERIDG GITGALRQEA
950
951
IDRFNAPGAQ QFCFLLSTRA GGLGINLATA DTVIIFDSDW NPHNDIQAFS
1000
1001
RAHRIGQANK VMIYRFVTRA SVEERITQVA KRKMMLTHLV VRPGLGSKAG
1050
1051
SMSKQELDDI LKFGTEELFK DENEGENKEE DSSVIHYDNE AIARLLDRNQ
1100
1101
DATDDTDVQN MNEYLSSFKV AQYVVREEDK IEEIEREIIK QEENVDPDYW
1150
1151
EKLLRHHYEQ QQEDLARNLG KGKRVRKQVN YNDAAQEDQD NQSEYSVGSE
1200
1201
EEDEDFDERP EGRRQSKRQL RNEKDKPLPP LLARVGGNIE VLGFNTRQRK
1250
1251
AFLNAVMRWG MPPQDAFTTQ WLVRDLRGKT EKEFKAYVSL FMRHLCEPGA
1300
1301
DGSETFADGV PREGLSRQQV LTRIGVMSLV KKKVQEFEHI NGRWSMPELM
1350
1351
PDPSADSKRS SRASSPTKTS PTTPEASTTN SPCTSKPATP APSEKGDGVR
1400
1401
TLLEKDDTEN PEEKPEKSSK VGEKMETEID SPSPAPSLGE RLEHRKILLE
1450
1451
DDAPGVPGEI EPEPGYRGDR EKSASEPTPG ERGEEKPLDG QEHRERTEGE
1500
1501
TGDLGKREDV KADRELRLGP PRDEPRPNGR REEKVEKPRF MFNIADGGFT
1550
1551
ELHTLWQNEE RAAISSGKLN EIWHRRHDYW LLAGIVLHGY ARWQDIQNDA
1600
1601
QFAIINEPFK TEANKGNFLE MKNKFLARRF KLLEQALVIE EQLRRAAYLN
1650
1651
LSQEPAHPAM ALHARFAEAE CLAESHQHLS KESLAGNKPA NAVLHKVLNQ
1700
1701
LEELLSDMKA DVTRLPATLS RIPPIAARLQ MSERSILSRL ASKGTEPHPT
1750
1751
PAFPPGPYAT PPGYGAAFSA APVGALAAAG ANYSQMPAGS FITATTNGPP
1800
1801
VLVKKEKEMV GALVSDGLGL DRKEPRAGEV ICIDD                
1835
 

Show the unformatted sequence.

Checksums:
CRC64:A1190EB1BA671D27
MD5:185c6d9c13b75df7efc2ce29a5fdbb3b

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;