Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1M0M3_RAT (F1M0M3)

Summary

This is the summary of UniProt entry F1M0M3_RAT (F1M0M3).

Description: UEV and lactate/malate dehyrogenase domains {ECO:0000313|Ensembl:ENSRNOP00000049188}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 470 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam UEV 21 141
Pfam Ldh_1_N 183 316
Pfam Ldh_1_C 319 468

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1M0M3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEFDCEGVRR LLGKYKFRDL TVEELKTVNM SFPHFRYSMD TYVFKDTSQK
50
51
DLLNFTGTIP VMYQGKTYNI PIRFWILDSH PFAPPICFLK PTANMEISVG
100
101
KHVDAKGRIY LPYLQNWSHP KSVIVGLIKE MIAKFQEELP LYSVPSSNEA
150
151
QQVDLLAYIT KITEGVSDIN SRGWTNHENK IPNKITVVGS GDLGIACTLA
200
201
ISAKGIADKL LLLDLSDGTN QGTMDLDIFN LPNVEISKDL SASAHSKVVI
250
251
FTANSLGGSE SYLHAVQSNV DMFRALVPAL GHYSQHAVLL VASQPVEIMS
300
301
YVTWKLSTFP AARVMGIGCN LDSQRLQYII SSVLKAQTSG KEVWVVGEQG
350
351
ENKVCSWSGQ DGVMSPSSQA QLSSRAMGLL KVKGQRSWSV GLSVADLLDT
400
401
IINNKKKVHS VSTLAKGYYG LDNEVFLSLP CILGTSGVSE VLKTAAEDAV
450
451
TEALQTSASS IHGLQQQLKL                                 
470
 

Show the unformatted sequence.

Checksums:
CRC64:48E4915E285B66B6
MD5:cf87cf19da496b4642cc122519cff906

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;