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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1Q9E8_DANRE (F1Q9E8)

Summary

This is the summary of UniProt entry F1Q9E8_DANRE (F1Q9E8).

Description: DNA ligase {ECO:0000256|RuleBase:RU000617}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 909 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 2
Pfam DNA_ligase_A_N 20 213
disorder n/a 115 118
Pfam DNA_ligase_A_M 253 456
disorder n/a 420 422
Pfam DNA_ligase_A_C 481 593
disorder n/a 618 623
disorder n/a 626 633
low_complexity n/a 629 640
Pfam BRCT_2 659 746
Pfam DNA_ligase_IV 754 787
coiled_coil n/a 771 791
Pfam BRCT 844 896

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1Q9E8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MESVSKSDAK PQAFVAAQVP FIHLCTVLEK IQKTKLRPDK SKILKEFIDS
50
51
WRNFHAALHK DNPDTADSFY AVMRLIVPSF ERERMAYGIK ENMLAKLYIE
100
101
VLGLPKNGDE ANKLLNYRAP TTSQGEAGDF ALMAYFVLKK RCTSQGNLSI
150
151
KEVNDFLDSV AINNASKQKD QVKKSLLHLI TQSSALEQKW LIRMILKDMK
200
201
LGISKETVLQ VFHPDAPEFY NVTTDLNKVC RQLHDPSVSL SEVSIDLFSA
250
251
FKPMLAAVAN IRQIEKQMGN RPFYIETKLD GERIQLHKAG DVYKYYTRNS
300
301
YEYTQQFGAS PLEGSLTPYI HNVFSPHVVN CILDGEMMAY NPKTETFMQK
350
351
GSKFDIKRLV DDSDLQTCFC VFDVLLINNQ KFGKEPLKKR YESLETVFSP
400
401
IKGRIHLVSK SEGRTMQEVV NSLNEAIDNR EEGIMVKDPM SIYKPDKRGE
450
451
GWLKIKPEYV DGLMDELDLL IVGGYWGKGR RSGMLSHFLC AVAEVPSPGE
500
501
KPTVFHTLCR IGSGYTLKEL YDLGVKLAKH WKVYNKNNPP AAILCGTEKP
550
551
EVYIEPRNSV ILQVKAAEIV TSEMYKTDCT LRFPRIERIR EDKEWHQCMT
600
601
LDDLNQFRSK ASGKLASRHL NIHEDQPEKK KRKIVAKPKK TIGVIDHFKS
650
651
QDLSKVAKET DMFEEVEFCV INGDDEHSKA ELEKGVARCG GIVVQNPGKD
700
701
TYCAIAAVQN MRVKNLISSD QHDVVWATWL LECLENKQVI PWQPRHMIHM
750
751
SPSTREHFAK EYDQYGDSYY VDTSEQQLRD VIERISSAEV KSLSVAQIEA
800
801
ENAWDDLPTS IFRPYSAYFD RCADIGDPKS VICGTCLDTR ALEFRFHGGK
850
851
VVEKLKEGIS HVVVEDMKRA LDLKTLRRLH AKKFKIVHES WVTDSIKAGH
900
901
VKDEIDYLI                                             
909
 

Show the unformatted sequence.

Checksums:
CRC64:C036F5B68464B171
MD5:97d38feb640c732623d85a9162325f11

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;