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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1QLR3_DANRE (F1QLR3)

Summary

This is the summary of UniProt entry F1QLR3_DANRE (F1QLR3).

Description: Fragile X mental retardation, autosomal homolog 1 {ECO:0000313|Ensembl:ENSDARP00000095251}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 622 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Tudor_FRX1 4 52
disorder n/a 43 45
disorder n/a 47 48
disorder n/a 55 56
low_complexity n/a 56 67
disorder n/a 60 61
Pfam Agenet 62 117
disorder n/a 63 65
Pfam KH_9 123 207
coiled_coil n/a 202 222
disorder n/a 210 211
Pfam KH_1 220 280
Pfam KH_1 283 353
disorder n/a 319 321
disorder n/a 329 332
Pfam FXMRP1_C_core 354 477
disorder n/a 377 622
low_complexity n/a 458 489
Pfam FXR_C1 482 557
low_complexity n/a 523 532
Pfam FXR_C3 575 621

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1QLR3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEELTVEVRG SNGAYYKGFV RDVHDDSLSI SFENNWQPER QVPFSDVRLP
50
51
PSADTKKEIG EGEEVEIFSR ANEQEPCGWW LAKVRMMKGD FYVIEYAACD
100
101
ATYNEIVTFE RLRPVNRNKA VTESTFFRCS VPVPEDLRAA CESEQAHKEF
150
151
KKAVGAIRIV YSPEKSELVV LSLSEATVKR VSLLSDIHLR SIRTKLMLMS
200
201
RNQEATKHLE STKQLASAFQ EEFTVREDLM GLAIGSHGSN IQQARKVPGV
250
251
TAIELEEETG TFRIYGESTE AVQKARNYLE FLEDSVQIPR NLVGKVIGKN
300
301
GKVIQEIVDK SGVVRVRIEG DNDNKLPRQE GMVPFTFVGT KESISNVQVL
350
351
LEYHIAYLNE VEQLRLERLQ IDEQLRQIGM GFRSVPNRPA DKEKGFGPDE
400
401
SSSGSIHTQR SYRGRGRRGP AHTSAYGTNS EHSYTSETDS ERKAELSDWS
450
451
LAADESERNP RPQRDSRRRD LRGRGRGSRG RGASNSISSV LKDPDGNPYS
500
501
LLDNTETDQT ADTDGSESQM NTSRRRRSRR RRTDEDTTVM DGMSESDNAS
550
551
LSENGLVTVA DYISRAESQS RQTNPRDTRK SKKDMTRGDF ISEHSAAESV
600
601
SNGPNNADEP SESAKAVVNG VS                              
622
 

Show the unformatted sequence.

Checksums:
CRC64:7BF7FB7FE1AFD4BF
MD5:4feda4743f8b0d6191380043e5d6d1ce

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;