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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: F1RBT2_DANRE (F1RBT2)

Summary

This is the summary of UniProt entry F1RBT2_DANRE (F1RBT2).

Description: DNA helicase {ECO:0000256|ARBA:ARBA00012551}
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1953 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 148
low_complexity n/a 29 49
low_complexity n/a 63 84
low_complexity n/a 91 106
low_complexity n/a 104 124
low_complexity n/a 124 137
Pfam CHDNT 155 210
disorder n/a 200 222
low_complexity n/a 214 230
disorder n/a 232 369
low_complexity n/a 239 273
low_complexity n/a 289 302
low_complexity n/a 294 312
low_complexity n/a 319 369
Pfam PHD 377 422
disorder n/a 427 451
low_complexity n/a 427 454
Pfam PHD 459 504
disorder n/a 513 515
disorder n/a 517 541
low_complexity n/a 521 535
low_complexity n/a 528 542
disorder n/a 589 603
disorder n/a 605 610
Pfam Chromo 633 684
low_complexity n/a 697 706
disorder n/a 698 710
disorder n/a 713 717
Pfam SNF2-rel_dom 739 1035
low_complexity n/a 915 929
Pfam Helicase_C 1060 1174
low_complexity n/a 1061 1073
disorder n/a 1240 1244
disorder n/a 1247 1253
disorder n/a 1264 1280
low_complexity n/a 1293 1307
disorder n/a 1294 1312
Pfam DUF1087 1296 1358
disorder n/a 1319 1327
disorder n/a 1331 1416
low_complexity n/a 1358 1375
Pfam CHDII_SANT-like 1392 1533
disorder n/a 1454 1456
disorder n/a 1485 1496
disorder n/a 1527 1731
low_complexity n/a 1599 1610
low_complexity n/a 1608 1621
low_complexity n/a 1672 1683
low_complexity n/a 1691 1701
Pfam CHDCT2 1768 1914
disorder n/a 1858 1859
disorder n/a 1876 1885
coiled_coil n/a 1890 1910
disorder n/a 1937 1953

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F1RBT2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGSEDDRDR FEPMGDDIEE QISETDTPKS KKKKKAKKSR ESRTSKRQKV
50
51
IREEIAVSSP EVMEAIRMAE GEEEEDRVMR SESEGSDYAP SKKKKKRSSS
100
101
SKDRKKGSAG EKAGGSGGKS KRKEPEPEEE DDDDDDDGQE PKSSSQLLAD
150
151
WGMKDIDYTF TQEDYNSLTN YKAFSQFVRP LIAAKNPKIA VSKMMMVLGA
200
201
KWREFSTNNP MRGSASANAA LAAANVAAAV ESMVTKVDAG GGGGPALATA
250
251
PPTTTAAPVA APPPPQQPPA VPLRKAKTKE GKGPNARRKT KPTPKPQDKK
300
301
SKAKKVAPLK IKLGNFKRKR SSSGEEDDGE SDFDSFSVSD GSNSRSSRSK
350
351
NKKAKSSKKK KKMDEDADGY ETDHQDYCEV CQQGGEIILC DTCPRAYHMV
400
401
CLDPDMERAP EGTWSCPHCE KEGIQWEARE ESSEGEEEND DGRRDDGDVE
450
451
EEDDHHMEFC RVCKDGGELL CCDTCPSSYH LHCLNPPLPD IPNGEWICPR
500
501
CLSPPLKGKV QKVLTWRWGE APPPMPVPRP ADLPAEAPDP PPMIGRKERE
550
551
FFVKWCNKSY WHCSWVQELQ LELNCQVMFR NYQRKTDMEE PPNLEMGAEG
600
601
DEDKSCKRKN KDPFYARMED KYGRFGVKIE WLFIHRILNH SVDKKNNVHY
650
651
LIKWRDLPYD QSTWESEDMD VPDFETYKQH YWNHRELMLG EEGRPGKKMK
700
701
KVKVRKTERP PANPVVDPTI KFDRQPDYLD STGGTLHPYQ LEGLNWLRFS
750
751
WAQGTDTILA DEMGLGKTVQ TAVFLYSLYK EGHSKGPFLV SAPLSTIINW
800
801
EREFEMWAPD MYVVTYVGDK DSRAVIRENE FTFEDNAIRG GKKASKMKKE
850
851
AAVKFHVLLT SYELITIDQA ILGSIDWACL VVDEAHRLKN NQSKFFRVLN
900
901
NYPLQHKLLL TGTPLQNNLE ELFHLLNFLT PERFNNLEGF LEEFADIAKE
950
951
DQIKKLHDML GPHMLRRLKA DVFKHMPSKT ELIVRVELSP MQKKYYKYIL
1000
1001
TRNFEALNTR GGGNQVSLLN VVMDLKKCCN HPYLFPTAAT EAPKMPNGMY
1050
1051
DGSALTKASG KLMLLFKMLK KLKEGGHRVL IFSQMTKMLD LLEDFLENEG
1100
1101
YKYERIDGGV TGGMRQEAID RFNAPGAPQF VFLLSTRAGG LGINLATADT
1150
1151
VIIYDSDWNP HNDIQAFSRA HRIGQNKKVM IYRFVTKASV EERITQVAKK
1200
1201
KMMLTHLVVR PGLGSKAGSM SKQELDDILK FGTEQLFKDE LGEGDNKEED
1250
1251
SSVIHYDDKA IDRLLDRNQD ATEDTELQSM NEYLSSFKVA QYVVKDEDEE
1300
1301
EEDVDREIIK QEESVDPDYW EKLLRHHYEQ QQEDLARHLG KGKRPRKPVN
1350
1351
YNDCSQEDRG SRRDWQDDQS DNQSDYSVAS EEGDEDFDER SEAANSRRPS
1400
1401
RKGLRNDKDK PLPPLLARVG GNIEVLGFNA RQRKAFLNAV MRYGMPPQDA
1450
1451
FTTQWLVRDL RGKSEKEFKA YVSLFMRHLC EPGADGAETF ADGVPREGLS
1500
1501
RQHVLTRIGV MSLIRKKVQE FEHVNGQWSM PWMKELEESK RAAAIAAGED
1550
1551
PKTPSTGTPA DTQPNTPAPE DLSKTEDIKE LEEKTEGDGE KEVKGSRQED
1600
1601
EIIEIPDEGE KSPSSAKKEE KTDKESEASS EKDGGSRENE KDGEKEKSAE
1650
1651
SKENMSSDVK ADGSDATNSG DSTKTKEESS EEKMDTSPAS DEKKELKDEK
1700
1701
DGVKPEDSAK LQNGENAKET SGGGDGVSEE KKKAVKQRFM FNIADGGFTE
1750
1751
LHSLWQNEER AATVTKKTYE IWHRRHDYWL LAGIIFHGYA RWQDVQNDPR
1800
1801
FAILNEPFKG EMSRGNFLEI KNKFLARRFK LLEQALVIEE QLRRAAYLNM
1850
1851
TEDPSHPSMA LNTRFSEVEC LAESHQHLSK ESMSGNKPAN AVLHKVLKQL
1900
1901
EELLSDMKAD VTRLPATIAR IPPVAVRLQM SERSILSRLA SRGPEVTQTQ
1950
1951
AQR                                                   
1953
 

Show the unformatted sequence.

Checksums:
CRC64:DB5F3C64887F1C04
MD5:1668fa854dc9cee8a9643c43ca1137c8

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;