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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ARI4A_MOUSE (F8VPQ2)

Summary

This is the summary of UniProt entry ARI4A_MOUSE (F8VPQ2).

Description: AT-rich interactive domain-containing protein 4A {ECO:0000303|PubMed:15922553, ECO:0000312|MGI:MGI:2444354}
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1261 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 28 43
disorder n/a 62 63
disorder n/a 118 123
disorder n/a 125 126
disorder n/a 131 138
disorder n/a 142 169
low_complexity n/a 152 167
Pfam RBB1NT 170 262
low_complexity n/a 267 281
disorder n/a 275 309
low_complexity n/a 278 311
coiled_coil n/a 288 308
Pfam ARID 311 397
disorder n/a 411 412
low_complexity n/a 411 422
disorder n/a 416 431
disorder n/a 435 472
disorder n/a 475 477
low_complexity n/a 480 490
disorder n/a 490 583
low_complexity n/a 496 511
low_complexity n/a 525 537
low_complexity n/a 539 561
low_complexity n/a 563 574
Pfam Tudor-knot 577 633
disorder n/a 587 588
disorder n/a 592 601
disorder n/a 633 634
disorder n/a 636 771
low_complexity n/a 641 669
coiled_coil n/a 645 665
low_complexity n/a 690 707
disorder n/a 773 778
disorder n/a 783 804
disorder n/a 807 837
disorder n/a 839 1051
low_complexity n/a 965 976
low_complexity n/a 991 1003
disorder n/a 1056 1180
disorder n/a 1185 1192
coiled_coil n/a 1190 1224
disorder n/a 1208 1209
disorder n/a 1211 1261
low_complexity n/a 1215 1226
low_complexity n/a 1229 1252

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession F8VPQ2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKAADEPAYL TVGTDVSAKY RGAFCEAKIK TVKRLVKVKV LLKQDNTTQL
50
51
VQDDQVKGPL RVGAIVETRT SDGSIQEAII SKLTDASWYT VVFDDGDERT
100
101
LRRTSLCLKG ERHFAESETL DQLPLTNPEH FGTPVIAKKT NRGRRSSLPI
150
151
TEDEKEEESS EEEDEDKRRL NDELLGKVVS VASTAESTGW YPALVVSPSC
200
201
NDDVTVKKDQ CLVRSFIDSK FYSIARKDIK ELDILTLPES ELCARPGLRR
250
251
ASVFLKGRIV PDNWKMDISE ILESSSSDDE ECPAEEHEEE KEKEAKKEEE
300
301
ELPEEELDPE ERDNFLQQLY KFMEDRGTPI NKPPVLGYKD LNLFKLFRLV
350
351
YHQGGCGNID SGAVWKQIYM DLGIPILNSA ASYNVKTAYR KYLYGFEEYC
400
401
RSANIQFRTI HHHEPKVKEE KKDFEDSMDE ALKEAPEMPL LDVKSEPEEN
450
451
TDSNSESDRE DTELKSPRGR RKIVRDANCI KKEIEEEKIE DKFLRDDLEN
500
501
KDAGDDDDDG DPAAKREHEL LFGRKSTPKN KEKKIKKPED SERDSDEEEE
550
551
KSQEREETES RCDSEGEDEE DDTEPCLTGT KVKVKYGRGK TQKIYEASIK
600
601
STEMDDGEIL YLVHYYGWNV RYDEWVKADR IIWPLDKGGP KKKQKKKVKN
650
651
KEDSEKDEKR DEERQKSKRG RPPLKSTFSP NMPYSLSKTS NSEGKSDSCS
700
701
SDSEADDQLE KSSGGEDLSP DVKEELEKNE NAHDDKLDEE NPKIVHISKE
750
751
NDRTQAQPSD TLTVEAGDSD QIVHIFGDKV DQVEEFKKQV EKSPKGKGRR
800
801
SKTKDLSLEL IKISPFGQEE AGSEAHGDVH SLEFSSLECK NFSSTEDDID
850
851
PYEKEKKLKR KILGQQSPEK KLRLDNGMEM TTGVSQERSD DGAGAEGMKG
900
901
AHVEQHFETE GEGMPSLTAE PDQGLQELTS EKSDSPAEEE PVHTPLKEEE
950
951
DAMPLIGPET LVCHEVDLDD LDEKDKTSIE DVVVEGSESN SLASVPPALP
1000
1001
PVAQHNFSVA SPLTLSQDES RSIKSESDIT IEVDSIAEES QEGLCERESA
1050
1051
NGFEASVASG ACSIIAHERE SREKGQKRPS DGNSGLIAKK QKRTPKRTSA
1100
1101
AAKTEKNGAG QSSDSEDLPA MDSSSNCTPV KRLTLPKSQK LPRSPARTSP
1150
1151
HIKDAEKEKH REKHPNSSPR TYKWSFQLNE LDNMNSTERI SFLQEKLQEI
1200
1201
RKYYMSLKSE VATIDRRRKR LKKKDREVSH AGASMSSASS DTGMSPSSSS
1250
1251
PPQNVLAVEC R                                          
1261
 

Show the unformatted sequence.

Checksums:
CRC64:4392BF421E3A00B8
MD5:7e1aed600a357f49097ee6f99a4872f1

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;