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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: G3V749_RAT (G3V749)

Summary

This is the summary of UniProt entry G3V749_RAT (G3V749).

Description: Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 558 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 65
low_complexity n/a 4 13
Pfam WGR 94 174
disorder n/a 190 207
Pfam PARP_reg 207 337
Pfam PARP 351 552
low_complexity n/a 378 389
disorder n/a 487 489

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession G3V749. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAPRRRRSGC GRRVLNEAKR VDNGNRATDD SPPGKKVRTC QKKGPAAGGE
50
51
DTDRTKGKQD SVKTLLVKGR APVDPECTSK VGKAHVYCEG DDVYDVMLNQ
100
101
TNLQFNNNKY YLIQLLEDDA QQNFSVWMRW GRVGKTGQHS LVACSGDLNK
150
151
AKEIFQKKFL DKTKNNWEDR ENFEKVPGKY DMLQMDYAAS TEDENKTKQE
200
201
ETSKPESQLD LRVQELLKLI CNVQTMEEMM IEMKYDTKRA PLGKLTVAQI
250
251
KAGYQSLKKI EDCIRAGQHG RALVEACNEF YTRIPHDFGL SIPPVIRTEK
300
301
ELSDKVKLLE ALGDIEIALK LVKSERQGLE HPLDQHYRNL RCALRPLDHE
350
351
SHEFKVISQY LQSTHAPTHK DYTMTLLEVF EVEKEGEKEA FRKDLPNRML
400
401
LWHGSRLSNW VGILSHGLRV APPEAPITGY MFGKGIYFAD MSSKSANYCF
450
451
ASRLKNTGLL LLSEVALGQC NELLEANPKA EGLLQGKHST KGMGKMAPSP
500
501
AHFITLNGST VPLGPASDTG ILNPEGYTLN YNEFIVYSPS QVHMRYLLKI
550
551
QFNFLQLW                                              
558
 

Show the unformatted sequence.

Checksums:
CRC64:0DD029197CEC8A93
MD5:e377fe720a990b9c58d6f47d8700cd70

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;