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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: BACH_HUMAN (O00154)

Summary

This is the summary of UniProt entry BACH_HUMAN (O00154).

Description: Cytosolic acyl coenzyme A thioester hydrolase EC=3.1.2.2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 380 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam 4HBT 68 151
disorder n/a 181 182
disorder n/a 185 187
disorder n/a 190 199
disorder n/a 210 211
disorder n/a 217 218
Pfam 4HBT 242 317
disorder n/a 343 356
disorder n/a 358 380

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O00154. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKLLARALRL CEFGRQASSR RLVAGQGCVG PRRGCCAPVQ VVGPRADLPP
50
51
CGACITGRIM RPDDANVAGN VHGGTILKMI EEAGAIISTR HCNSQNGERC
100
101
VAALARVERT DFLSPMCIGE VAHVSAEITY TSKHSVEVQV NVMSENILTG
150
151
AKKLTNKATL WYVPLSLKNV DKVLEVPPVV YSRQEQEEEG RKRYEAQKLE
200
201
RMETKWRNGD IVQPVLNPEP NTVSYSQSSL IHLVGPSDCT LHGFVHGGVT
250
251
MKLMDEVAGI VAARHCKTNI VTASVDAINF HDKIRKGCVI TISGRMTFTS
300
301
NKSMEIEVLV DADPVVDSSQ KRYRAASAFF TYVSLSQEGR SLPVPQLVPE
350
351
TEDEKKRFEE GKGRYLQMKA KRQGHAEPQP                      
380
 

Show the unformatted sequence.

Checksums:
CRC64:BDD75D62A60095BC
MD5:3a034ae016d184691b846eb562a0f985

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
4HBT 242 - 314 2QQ2 L 232 - 304 Jmol OpenAstexViewer
242 - 315 2QQ2 E 232 - 305 Jmol OpenAstexViewer
G 232 - 305 Jmol OpenAstexViewer
J 232 - 305 Jmol OpenAstexViewer
242 - 316 2QQ2 A 232 - 306 Jmol OpenAstexViewer
F 232 - 306 Jmol OpenAstexViewer
242 - 317 2QQ2 B 232 - 307 Jmol OpenAstexViewer
C 232 - 307 Jmol OpenAstexViewer
D 232 - 307 Jmol OpenAstexViewer
H 232 - 307 Jmol OpenAstexViewer
I 232 - 307 Jmol OpenAstexViewer
K 232 - 307 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.