Summary
This is the summary of UniProt entry MYO1C_HUMAN (O00159).
Description: | Unconventional myosin-Ic |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 1063 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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Source | Domain | Start | End |
---|---|---|---|
Pfam | Myosin_head | 48 | 718 |
disorder | n/a | 137 | 141 |
disorder | n/a | 168 | 169 |
low_complexity | n/a | 243 | 259 |
Pfam | IQ | 735 | 755 |
Pfam | IQ | 758 | 777 |
low_complexity | n/a | 774 | 784 |
low_complexity | n/a | 839 | 850 |
Pfam | Myosin_TH1 | 874 | 1055 |
low_complexity | n/a | 968 | 981 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O00159. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MALQVELVPT GEIIRVVHPH RPCKLALGSD GVRVTMESAL TARDRVGVQD
50 51
FVLLENFTSE AAFIENLRRR FRENLIYTYI GPVLVSVNPY RDLQIYSRQH
100 101
MERYRGVSFY EVPPHLFAVA DTVYRALRTE RRDQAVMISG ESGAGKTEAT
150 151
KRLLQFYAET CPAPERGGAV RDRLLQSNPV LEAFGNAKTL RNDNSSRFGK
200 201
YMDVQFDFKG APVGGHILSY LLEKSRVVHQ NHGERNFHIF YQLLEGGEEE
250 251
TLRRLGLERN PQSYLYLVKG QCAKVSSIND KSDWKVVRKA LTVIDFTEDE
300 301
VEDLLSIVAS VLHLGNIHFA ANEESNAQVT TENQLKYLTR LLSVEGSTLR
350 351
EALTHRKIIA KGEELLSPLN LEQAAYARDA LAKAVYSRTF TWLVGKINRS
400 401
LASKDVESPS WRSTTVLGLL DIYGFEVFQH NSFEQFCINY CNEKLQQLFI
450 451
ELTLKSEQEE YEAEGIAWEP VQYFNNKIIC DLVEEKFKGI ISILDEECLR
500 501
PGEATDLTFL EKLEDTVKHH PHFLTHKLAD QRTRKSLGRG EFRLLHYAGE
550 551
VTYSVTGFLD KNNDLLFRNL KETMCSSKNP IMSQCFDRSE LSDKKRPETV
600 601
ATQFKMSLLQ LVEILQSKEP AYVRCIKPND AKQPGRFDEV LIRHQVKYLG
650 651
LLENLRVRRA GFAYRRKYEA FLQRYKSLCP ETWPTWAGRP QDGVAVLVRH
700 701
LGYKPEEYKM GRTKIFIRFP KTLFATEDAL EVRRQSLATK IQAAWRGFHW
750 751
RQKFLRVKRS AICIQSWWRG TLGRRKAAKR KWAAQTIRRL IRGFVLRHAP
800 801
RCPENAFFLD HVRTSFLLNL RRQLPQNVLD TSWPTPPPAL REASELLREL
850 851
CIKNMVWKYC RSISPEWKQQ LQQKAVASEI FKGKKDNYPQ SVPRLFISTR
900 901
LGTDEISPRV LQALGSEPIQ YAVPVVKYDR KGYKPRSRQL LLTPNAVVIV
950 951
EDAKVKQRID YANLTGISVS SLSDSLFVLH VQRADNKQKG DVVLQSDHVI
1000 1001
ETLTKTALSA NRVNSININQ GSITFAGGPG RDGTIDFTPG SELLITKAKN
1050 1051
GHLAVVAPRL NSR
1063
Show the unformatted sequence. |
Checksums: |
CRC64:B105197BA07317B8
MD5:43b0fd63a55982a8051c59f3610eab1d
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
---|---|---|---|---|---|
IQ | 735 - 755 | 4BYF | A | 700 - 720 | Show 3D Structure View in InterPro |
C | 700 - 720 | Show 3D Structure View in InterPro | |||
Myosin_head | 48 - 718 | 4BYF | A | 13 - 683 | Show 3D Structure View in InterPro |
C | 13 - 683 | Show 3D Structure View in InterPro |
The parts of the structure corresponding to the Pfam family are highlighted in blue.
Loading Structure Data
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
Very High (pLDDT > 90) | |
Confident (90 > pLDDT > 70) | |
Low (70 > pLDDT > 50) | |
Very Low (pLDDT < 50) |