Summary
This is the summary of UniProt entry MASP2_HUMAN (O00187).
Description: | Mannan-binding lectin serine protease 2 EC=3.4.21.104 |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 686 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
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Source | Domain | Start | End |
---|---|---|---|
sig_p | n/a | 1 | 15 |
low_complexity | n/a | 2 | 9 |
Pfam | CUB | 24 | 134 |
Pfam | EGF_CA | 138 | 180 |
Pfam | CUB | 184 | 293 |
disorder | n/a | 195 | 196 |
Pfam | Sushi | 300 | 361 |
Pfam | Sushi | 366 | 430 |
Pfam | Trypsin | 445 | 679 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O00187. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MRLLTLLGLL CGSVATPLGP KWPEPVFGRL ASPGFPGEYA NDQERRWTLT
50 51
APPGYRLRLY FTHFDLELSH LCEYDFVKLS SGAKVLATLC GQESTDTERA
100 101
PGKDTFYSLG SSLDITFRSD YSNEKPFTGF EAFYAAEDID ECQVAPGEAP
150 151
TCDHHCHNHL GGFYCSCRAG YVLHRNKRTC SALCSGQVFT QRSGELSSPE
200 201
YPRPYPKLSS CTYSISLEEG FSVILDFVES FDVETHPETL CPYDFLKIQT
250 251
DREEHGPFCG KTLPHRIETK SNTVTITFVT DESGDHTGWK IHYTSTAQPC
300 301
PYPMAPPNGH VSPVQAKYIL KDSFSIFCET GYELLQGHLP LKSFTAVCQK
350 351
DGSWDRPMPA CSIVDCGPPD DLPSGRVEYI TGPGVTTYKA VIQYSCEETF
400 401
YTMKVNDGKY VCEADGFWTS SKGEKSLPVC EPVCGLSART TGGRIYGGQK
450 451
AKPGDFPWQV LILGGTTAAG ALLYDNWVLT AAHAVYEQKH DASALDIRMG
500 501
TLKRLSPHYT QAWSEAVFIH EGYTHDAGFD NDIALIKLNN KVVINSNITP
550 551
ICLPRKEAES FMRTDDIGTA SGWGLTQRGF LARNLMYVDI PIVDHQKCTA
600 601
AYEKPPYPRG SVTANMLCAG LESGGKDSCR GDSGGALVFL DSETERWFVG
650 651
GIVSWGSMNC GEAGQYGVYT KVINYIPWIE NIISDF
686
Show the unformatted sequence. |
Checksums: |
CRC64:ED952085FA115E21
MD5:44453fdad3b72140d79d9d471ee2e3b2
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.