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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: S28A1_HUMAN (O00337)

Summary

This is the summary of UniProt entry S28A1_HUMAN (O00337).

Description: Sodium/nucleoside cotransporter 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 649 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 6
disorder n/a 8 9
transmembrane n/a 81 104
low_complexity n/a 108 122
transmembrane n/a 110 128
low_complexity n/a 121 141
transmembrane n/a 148 167
low_complexity n/a 155 169
transmembrane n/a 179 195
Pfam Nucleos_tra2_N 183 256
transmembrane n/a 202 222
low_complexity n/a 209 220
transmembrane n/a 262 283
Pfam Gate 263 382
transmembrane n/a 295 318
transmembrane n/a 338 360
Pfam Nucleos_tra2_C 366 590
transmembrane n/a 367 386
low_complexity n/a 423 438
transmembrane n/a 424 446
transmembrane n/a 458 479
transmembrane n/a 532 556
transmembrane n/a 568 592
low_complexity n/a 601 611

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O00337. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MENDPSRRRE SISLTPVAKG LENMGADFLE SLEEGQLPRS DLSPAEIRSS
50
51
WSEAAPKPFS RWRNLQPALR ARSFCREHMQ LFRWIGTGLL CTGLSAFLLV
100
101
ACLLDFQRAL ALFVLTCVVL TFLGHRLLKR LLGPKLRRFL KPQGHPRLLL
150
151
WFKRGLALAA FLGLVLWLSL DTSQRPEQLV SFAGICVFVA LLFACSKHHC
200
201
AVSWRAVSWG LGLQFVLGLL VIRTEPGFIA FEWLGEQIRI FLSYTKAGSS
250
251
FVFGEALVKD VFAFQVLPII VFFSCVISVL YHVGLMQWVI LKIAWLMQVT
300
301
MGTTATETLS VAGNIFVSQT EAPLLIRPYL ADMTLSEVHV VMTGGYATIA
350
351
GSLLGAYISF GIDATSLIAA SVMAAPCALA LSKLVYPEVE ESKFRREEGV
400
401
KLTYGDAQNL IEAASTGAAI SVKVVANIAA NLIAFLAVLD FINAALSWLG
450
451
DMVDIQGLSF QLICSYILRP VAFLMGVAWE DCPVVAELLG IKLFLNEFVA
500
501
YQDLSKYKQR RLAGAEEWVG DRKQWISVRA EVLTTFALCG FANFSSIGIM
550
551
LGGLTSMVPQ RKSDFSQIVL RALFTGACVS LVNACMAGIL YMPRGAEVDC
600
601
MSLLNTTLSS SSFEIYQCCR EAFQSVNPEF SPEALDNCCR FYNHTICAQ 
649
 

Show the unformatted sequence.

Checksums:
CRC64:42E952443B46B102
MD5:e96ca9d6c8d69e344d43c4bfebcc336b

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.