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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: IMA4_HUMAN (O00505)

Summary

This is the summary of UniProt entry IMA4_HUMAN (O00505).

Description: Importin subunit alpha-4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 521 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 54
Pfam IBB 11 93
disorder n/a 56 63
Pfam Arm 103 144
Pfam Arm 146 186
Pfam Arm 188 229
Pfam Arm 232 271
Pfam Arm 273 313
Pfam Arm 315 355
Pfam Arm 357 397
Pfam Arm 400 440
Pfam Arm_3 447 499

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O00505. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAENPSLENH RIKSFKNKGR DVETMRRHRN EVTVELRKNK RDEHLLKKRN
50
51
VPQEESLEDS DVDADFKAQN VTLEAILQNA TSDNPVVQLS AVQAARKLLS
100
101
SDRNPPIDDL IKSGILPILV KCLERDDNPS LQFEAAWALT NIASGTSAQT
150
151
QAVVQSNAVP LFLRLLRSPH QNVCEQAVWA LGNIIGDGPQ CRDYVISLGV
200
201
VKPLLSFISP SIPITFLRNV TWVIVNLCRN KDPPPPMETV QEILPALCVL
250
251
IYHTDINILV DTVWALSYLT DGGNEQIQMV IDSGVVPFLV PLLSHQEVKV
300
301
QTAALRAVGN IVTGTDEQTQ VVLNCDVLSH FPNLLSHPKE KINKEAVWFL
350
351
SNITAGNQQQ VQAVIDAGLI PMIIHQLAKG DFGTQKEAAW AISNLTISGR
400
401
KDQVEYLVQQ NVIPPFCNLL SVKDSQVVQV VLDGLKNILI MAGDEASTIA
450
451
EIIEECGGLE KIEVLQQHEN EDIYKLAFEI IDQYFSGDDI DEDPCLIPEA
500
501
TQGGTYNFDP TANLQTKEFN F                               
521
 

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Checksums:
CRC64:C4FF132C3F346B7F
MD5:55e53cb7f483ba3d77d43512069b04a4

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.