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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: SPT5_SCHPO (O13936)

Summary

This is the summary of UniProt entry SPT5_SCHPO (O13936).

Description: Transcription elongation factor spt5
Source organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (NCBI taxonomy ID 284812)
Length: 990 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 210
low_complexity n/a 75 129
coiled_coil n/a 90 127
low_complexity n/a 131 143
Pfam Spt5_N 146 235
coiled_coil n/a 146 166
low_complexity n/a 148 177
coiled_coil n/a 194 214
disorder n/a 213 216
disorder n/a 218 220
disorder n/a 229 230
Pfam Spt5-NGN 241 325
low_complexity n/a 324 335
disorder n/a 385 386
disorder n/a 389 393
disorder n/a 444 447
Pfam KOW 523 554
disorder n/a 627 630
disorder n/a 632 635
disorder n/a 643 646
low_complexity n/a 645 654
disorder n/a 710 720
disorder n/a 731 732
disorder n/a 756 763
disorder n/a 771 772
disorder n/a 795 990
Pfam CTD 807 869
Pfam CTD 860 944
low_complexity n/a 960 975

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O13936. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDTNSPKSID KDANSTEVDA AEQDAASVKI NSTRASPNGS DLLNDDSEAA
50
51
KITTNEKQSS PVDSHNESPN DTTINKGEDG NENEVDNVNN NDKKEDEDNV
100
101
EENEEEADAN EEEEEDEEDD EEDEEDEDES GGGRRKRARH DRRNQFLDIE
150
151
AEVDEDEEEL EDEEDEIGRE DGFIEEEVGA DYVGDDRRHR ELDRQRQELQ
200
201
SVDAERLAEE YREKYGRSQT VVGDTSNVPQ RLLLPSVNDP NIWAVRCKIG
250
251
KEKDIVFTIM RKAMDLQYTS SPLEIISAFQ RDSLVGYIYV EARKQSHVLD
300
301
ALNGVLNVYT NNMILVPIKE MPDLLKVQKQ VVELLPGAYV RIRRGKYAGD
350
351
LAQVDNLSEN GLTARVRIVP RIDYSDGLKR KNSATRPQAR LFNESEAFKS
400
401
NPSKFSKRGP RLFLFNNEEF EDGFLVKDIR ISSLITEGVN PTLDEVSKFN
450
451
PNNEDLDLSS LALSVKGGHA EFQPGDHVEV YVGEQTGVSG VVENVRGSVI
500
501
TMVSSDGLRL DVPSRGLRKR FRHGDYVKVI AGKYKDDTGM VVRISKDEVT
550
551
FLSDTLMTEL TVFSRDLGEA SSAQAVNSAY ELHDLVQLDV NTVACIFSVD
600
601
RDTYKVIDQN GGVRTVLASQ ITMRHSNRRG VATDRNGAEI RIGDKVKEVG
650
651
GEGKQGTILH IYRAFVFLHN RDIAENNGVF SARSRNVATI AAKGARISAD
700
701
LTKMNPALSN GPALPPVANL KRTIGRDKAI GATVRIRRGP MKGLLGVIKD
750
751
TTDANARVEL HTGNKMVTIP KENLLYTTKT GELISYTEFI ERSRGIRPGS
800
801
ISTADGPNVP NWAQGARTPA VANGSRTPAW NTGSRTPAWN SGSKTPAWNS
850
851
GSRTPAWNSG NKTPAWNAGS RTPAWNSGNK TPAWNVGNKT PAWNSGAKTP
900
901
AWNAGNKTPS WNNGTKTPAW NANQTPMVAN GTNTSWGQTP AYGGFSETNW
950
951
DTEDNSKPYT APTPGAWAAP TPGGWDDEEG DSPKYVPPSP           
990
 

Show the unformatted sequence.

Checksums:
CRC64:6FF52652D1C8EE89
MD5:47f10ff4252d872002d469bba4bdc257

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CTD 829 - 832 4PZ8 B 3 - 6 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;