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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ARI1A_HUMAN (O14497)

Summary

This is the summary of UniProt entry ARI1A_HUMAN (O14497).

Description: AT-rich interactive domain-containing protein 1A
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 2285 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 156
low_complexity n/a 1 9
low_complexity n/a 5 21
low_complexity n/a 24 53
low_complexity n/a 75 97
low_complexity n/a 119 135
low_complexity n/a 133 146
disorder n/a 159 220
low_complexity n/a 159 167
low_complexity n/a 186 190
low_complexity n/a 186 190
low_complexity n/a 211 234
disorder n/a 223 341
low_complexity n/a 231 264
low_complexity n/a 271 293
low_complexity n/a 306 325
low_complexity n/a 317 330
low_complexity n/a 337 352
disorder n/a 343 1012
low_complexity n/a 364 370
low_complexity n/a 399 424
low_complexity n/a 446 473
low_complexity n/a 468 493
low_complexity n/a 493 576
low_complexity n/a 573 594
low_complexity n/a 609 620
low_complexity n/a 657 673
low_complexity n/a 693 706
low_complexity n/a 793 814
low_complexity n/a 812 823
low_complexity n/a 987 1009
Pfam ARID 1019 1104
disorder n/a 1039 1042
disorder n/a 1067 1070
disorder n/a 1072 1085
disorder n/a 1112 1629
low_complexity n/a 1122 1134
low_complexity n/a 1139 1153
low_complexity n/a 1326 1333
low_complexity n/a 1356 1366
low_complexity n/a 1395 1424
low_complexity n/a 1436 1442
low_complexity n/a 1566 1579
disorder n/a 1631 1660
disorder n/a 1747 1797
low_complexity n/a 1759 1786
disorder n/a 1799 1804
disorder n/a 1828 1830
disorder n/a 1838 1942
low_complexity n/a 1866 1878
low_complexity n/a 1885 1903
low_complexity n/a 1926 1937
disorder n/a 1947 1959
disorder n/a 1965 1966
Pfam BAF250_C 1976 2231
low_complexity n/a 2003 2021
disorder n/a 2026 2034
low_complexity n/a 2231 2241

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O14497. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAQVAPAAA SSLGNPPPPP PSELKKAEQQ QREEAGGEAA AAAAAERGEM
50
51
KAAAGQESEG PAVGPPQPLG KELQDGAESN GGGGGGGAGS GGGPGAEPDL
100
101
KNSNGNAGPR PALNNNLTEP PGGGGGGSSD GVGAPPHSAA AALPPPAYGF
150
151
GQPYGRSPSA VAAAAAAVFH QQHGGQQSPG LAALQSGGGG GLEPYAGPQQ
200
201
NSHDHGFPNH QYNSYYPNRS AYPPPAPAYA LSSPRGGTPG SGAAAAAGSK
250
251
PPPSSSASAS SSSSSFAQQR FGAMGGGGPS AAGGGTPQPT ATPTLNQLLT
300
301
SPSSARGYQG YPGGDYSGGP QDGGAGKGPA DMASQCWGAA AAAAAAAAAS
350
351
GGAQQRSHHA PMSPGSSGGG GQPLARTPQP SSPMDQMGKM RPQPYGGTNP
400
401
YSQQQGPPSG PQQGHGYPGQ PYGSQTPQRY PMTMQGRAQS AMGGLSYTQQ
450
451
IPPYGQQGPS GYGQQGQTPY YNQQSPHPQQ QQPPYSQQPP SQTPHAQPSY
500
501
QQQPQSQPPQ LQSSQPPYSQ QPSQPPHQQS PAPYPSQQST TQQHPQSQPP
550
551
YSQPQAQSPY QQQQPQQPAP STLSQQAAYP QPQSQQSQQT AYSQQRFPPP
600
601
QELSQDSFGS QASSAPSMTS SKGGQEDMNL SLQSRPSSLP DLSGSIDDLP
650
651
MGTEGALSPG VSTSGISSSQ GEQSNPAQSP FSPHTSPHLP GIRGPSPSPV
700
701
GSPASVAQSR SGPLSPAAVP GNQMPPRPPS GQSDSIMHPS MNQSSIAQDR
750
751
GYMQRNPQMP QYSSPQPGSA LSPRQPSGGQ IHTGMGSYQQ NSMGSYGPQG
800
801
GQYGPQGGYP RQPNYNALPN ANYPSAGMAG GINPMGAGGQ MHGQPGIPPY
850
851
GTLPPGRMSH ASMGNRPYGP NMANMPPQVG SGMCPPPGGM NRKTQETAVA
900
901
MHVAANSIQN RPPGYPNMNQ GGMMGTGPPY GQGINSMAGM INPQGPPYSM
950
951
GGTMANNSAG MAASPEMMGL GDVKLTPATK MNNKADGTPK TESKSKKSSS
1000
1001
STTTNEKITK LYELGGEPER KMWVDRYLAF TEEKAMGMTN LPAVGRKPLD
1050
1051
LYRLYVSVKE IGGLTQVNKN KKWRELATNL NVGTSSSAAS SLKKQYIQCL
1100
1101
YAFECKIERG EDPPPDIFAA ADSKKSQPKI QPPSPAGSGS MQGPQTPQST
1150
1151
SSSMAEGGDL KPPTPASTPH SQIPPLPGMS RSNSVGIQDA FNDGSDSTFQ
1200
1201
KRNSMTPNPG YQPSMNTSDM MGRMSYEPNK DPYGSMRKAP GSDPFMSSGQ
1250
1251
GPNGGMGDPY SRAAGPGLGN VAMGPRQHYP YGGPYDRVRT EPGIGPEGNM
1300
1301
STGAPQPNLM PSNPDSGMYS PSRYPPQQQQ QQQQRHDSYG NQFSTQGTPS
1350
1351
GSPFPSQQTT MYQQQQQNYK RPMDGTYGPP AKRHEGEMYS VPYSTGQGQP
1400
1401
QQQQLPPAQP QPASQQQAAQ PSPQQDVYNQ YGNAYPATAT AATERRPAGG
1450
1451
PQNQFPFQFG RDRVSAPPGT NAQQNMPPQM MGGPIQASAE VAQQGTMWQG
1500
1501
RNDMTYNYAN RQSTGSAPQG PAYHGVNRTD EMLHTDQRAN HEGSWPSHGT
1550
1551
RQPPYGPSAP VPPMTRPPPS NYQPPPSMQN HIPQVSSPAP LPRPMENRTS
1600
1601
PSKSPFLHSG MKMQKAGPPV PASHIAPAPV QPPMIRRDIT FPPGSVEATQ
1650
1651
PVLKQRRRLT MKDIGTPEAW RVMMSLKSGL LAESTWALDT INILLYDDNS
1700
1701
IMTFNLSQLP GLLELLVEYF RRCLIEIFGI LKEYEVGDPG QRTLLDPGRF
1750
1751
SKVSSPAPME GGEEEEELLG PKLEEEEEEE VVENDEEIAF SGKDKPASEN
1800
1801
SEEKLISKFD KLPVKIVQKN DPFVVDCSDK LGRVQEFDSG LLHWRIGGGD
1850
1851
TTEHIQTHFE SKTELLPSRP HAPCPPAPRK HVTTAEGTPG TTDQEGPPPD
1900
1901
GPPEKRITAT MDDMLSTRSS TLTEDGAKSS EAIKESSKFP FGISPAQSHR
1950
1951
NIKILEDEPH SKDETPLCTL LDWQDSLAKR CVCVSNTIRS LSFVPGNDFE
2000
2001
MSKHPGLLLI LGKLILLHHK HPERKQAPLT YEKEEEQDQG VSCNKVEWWW
2050
2051
DCLEMLRENT LVTLANISGQ LDLSPYPESI CLPVLDGLLH WAVCPSAEAQ
2100
2101
DPFSTLGPNA VLSPQRLVLE TLSKLSIQDN NVDLILATPP FSRLEKLYST
2150
2151
MVRFLSDRKN PVCREMAVVL LANLAQGDSL AARAIAVQKG SIGNLLGFLE
2200
2201
DSLAATQFQQ SQASLLHMQN PPFEPTSVDM MRRAARALLA LAKVDENHSE
2250
2251
FTLYESRLLD ISVSPLMNSL VSQVICDVLF LIGQS                
2285
 

Show the unformatted sequence.

Checksums:
CRC64:85BC5B6061625D8E
MD5:dd3d5c47207e822ebecdf6611e4dee92

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ARID 1019 - 1104 1RYU A 20 - 105 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.