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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: APOL1_HUMAN (O14791)

Summary

This is the summary of UniProt entry APOL1_HUMAN (O14791).

Description: Apolipoprotein L1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 398 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 27
disorder n/a 32 55
Pfam ApoL 78 392
coiled_coil n/a 108 128
coiled_coil n/a 148 168
low_complexity n/a 176 192
disorder n/a 297 298
disorder n/a 300 315
low_complexity n/a 340 353
coiled_coil n/a 361 395
disorder n/a 365 366
disorder n/a 368 370
low_complexity n/a 376 391

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O14791. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEGAALLRVS VLCIWMSALF LGVGVRAEEA GARVQQNVPS GTDTGDPQSK
50
51
PLGDWAAGTM DPESSIFIED AIKYFKEKVS TQNLLLLLTD NEAWNGFVAA
100
101
AELPRNEADE LRKALDNLAR QMIMKDKNWH DKGQQYRNWF LKEFPRLKSE
150
151
LEDNIRRLRA LADGVQKVHK GTTIANVVSG SLSISSGILT LVGMGLAPFT
200
201
EGGSLVLLEP GMELGITAAL TGITSSTMDY GKKWWTQAQA HDLVIKSLDK
250
251
LKEVREFLGE NISNFLSLAG NTYQLTRGIG KDIRALRRAR ANLQSVPHAS
300
301
ASRPRVTEPI SAESGEQVER VNEPSILEMS RGVKLTDVAP VSFFLVLDVV
350
351
YLVYESKHLH EGAKSETAEE LKKVAQELEE KLNILNNNYK ILQADQEL  
398
 

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Checksums:
CRC64:BD1A8F1D7C5A889F
MD5:af7b23430ae1aae11fae1014eaef2169

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.