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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: BACH1_HUMAN (O14867)

Summary

This is the summary of UniProt entry BACH1_HUMAN (O14867).

Description: Transcription regulator protein BACH1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 736 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam BTB 24 129
disorder n/a 171 172
disorder n/a 197 200
disorder n/a 244 258
disorder n/a 260 265
disorder n/a 281 313
disorder n/a 339 389
low_complexity n/a 375 394
disorder n/a 416 425
disorder n/a 439 441
disorder n/a 448 449
disorder n/a 478 480
low_complexity n/a 500 513
disorder n/a 507 514
Pfam bZIP_Maf 528 622
coiled_coil n/a 575 609
disorder n/a 593 594
disorder n/a 603 605
disorder n/a 663 668
disorder n/a 670 671
disorder n/a 679 713
disorder n/a 735 736

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O14867. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSLSENSVFA YESSVHSTNV LLSLNDQRKK DVLCDVTIFV EGQRFRAHRS
50
51
VLAACSSYFH SRIVGQADGE LNITLPEEVT VKGFEPLIQF AYTAKLILSK
100
101
ENVDEVCKCV EFLSVHNIEE SCFQFLKFKF LDSTADQQEC PRKKCFSSHC
150
151
QKTDLKLSLL DQRDLETDEV EEFLENKNVQ TPQCKLRRYQ GNAKASPPLQ
200
201
DSASQTYESM CLEKDAALAL PSLCPKYRKF QKAFGTDRVR TGESSVKDIH
250
251
ASVQPNERSE NECLGGVPEC RDLQVMLKCD ESKLAMEPEE TKKDPASQCP
300
301
TEKSEVTPFP HNSSIDPHGL YSLSLLHTYD QYGDLNFAGM QNTTVLTEKP
350
351
LSGTDVQEKT FGESQDLPLK SDLGTREDSS VASSDRSSVE REVAEHLAKG
400
401
FWSDICSTDT PCQMQLSPAV AKDGSEQISQ KRSECPWLGI RISESPEPGQ
450
451
RTFTTLSSVN CPFISTLSTE GCSSNLEIGN DDYVSEPQQE PCPYACVISL
500
501
GDDSETDTEG DSESCSAREQ ECEVKLPFNA QRIISLSRND FQSLLKMHKL
550
551
TPEQLDCIHD IRRRSKNRIA AQRCRKRKLD CIQNLESEIE KLQSEKESLL
600
601
KERDHILSTL GETKQNLTGL CQKVCKEAAL SQEQIQILAK YSAADCPLSF
650
651
LISEKDKSTP DGELALPSIF SLSDRPPAVL PPCARGNSEP GYARGQESQQ
700
701
MSTATSEQAG PAEQCRQSGG ISDFCQQMTD KCTTDE               
736
 

Show the unformatted sequence.

Checksums:
CRC64:CAAEECC63D46571B
MD5:bee72cf4ebba7d1bb4964d0f16bf7a15

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
BTB 24 - 120 2IHC B 24 - 120 Jmol OpenAstexViewer
24 - 126 2IHC A 24 - 126 Jmol OpenAstexViewer
24 - 127 2IHC C 24 - 127 Jmol OpenAstexViewer
D 24 - 127 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.