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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: IRF6_HUMAN (O14896)

Summary

This is the summary of UniProt entry IRF6_HUMAN (O14896).

Description: Interferon regulatory factor 6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 467 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam IRF 9 114
disorder n/a 39 45
disorder n/a 47 59
disorder n/a 67 75
disorder n/a 78 79
disorder n/a 108 110
disorder n/a 121 158
low_complexity n/a 134 150
disorder n/a 161 162
disorder n/a 177 180
disorder n/a 192 199
disorder n/a 202 205
Pfam IRF-3 224 407
disorder n/a 451 467

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O14896. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MALHPRRVRL KPWLVAQVDS GLYPGLIWLH RDSKRFQIPW KHATRHSPQQ
50
51
EEENTIFKAW AVETGKYQEG VDDPDPAKWK AQLRCALNKS REFNLMYDGT
100
101
KEVPMNPVKI YQVCDIPQPQ GSIINPGSTG SAPWDEKDND VDEEDEEDEL
150
151
DQSQHHVPIQ DTFPFLNING SPMAPASVGN CSVGNCSPEA VWPKTEPLEM
200
201
EVPQAPIQPF YSSPELWISS LPMTDLDIKF QYRGKEYGQT MTVSNPQGCR
250
251
LFYGDLGPMP DQEELFGPVS LEQVKFPGPE HITNEKQKLF TSKLLDVMDR
300
301
GLILEVSGHA IYAIRLCQCK VYWSGPCAPS LVAPNLIERQ KKVKLFCLET
350
351
FLSDLIAHQK GQIEKQPPFE IYLCFGEEWP DGKPLERKLI LVQVIPVVAR
400
401
MIYEMFSGDF TRSFDSGSVR LQISTPDIKD NIVAQLKQLY RILQTQESWQ
450
451
PMQPTPSMQL PPALPPQ                                    
467
 

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Checksums:
CRC64:7E28F5E0F5BA4053
MD5:97b2426090f3252ffbafb90380efaf28

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.