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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PDZD2_HUMAN (O15018)

Summary

This is the summary of UniProt entry PDZD2_HUMAN (O15018).

Description: PDZ domain-containing protein 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 2839 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 53 57
disorder n/a 63 65
low_complexity n/a 96 106
disorder n/a 98 99
disorder n/a 101 107
disorder n/a 131 133
disorder n/a 135 137
disorder n/a 184 321
low_complexity n/a 188 201
Pfam PDZ 334 416
disorder n/a 344 351
disorder n/a 357 368
disorder n/a 372 374
disorder n/a 426 431
disorder n/a 437 503
low_complexity n/a 447 459
disorder n/a 516 518
disorder n/a 520 521
disorder n/a 526 527
disorder n/a 529 538
disorder n/a 541 548
disorder n/a 559 560
Pfam PDZ 587 671
disorder n/a 678 729
low_complexity n/a 697 714
Pfam PDZ 728 811
disorder n/a 759 760
disorder n/a 766 769
disorder n/a 771 774
disorder n/a 776 779
disorder n/a 808 857
disorder n/a 876 927
disorder n/a 932 933
disorder n/a 935 959
disorder n/a 961 1033
disorder n/a 1036 1080
disorder n/a 1084 1184
disorder n/a 1202 1511
low_complexity n/a 1453 1468
disorder n/a 1530 1623
low_complexity n/a 1591 1600
disorder n/a 1628 1629
disorder n/a 1634 1713
low_complexity n/a 1661 1674
disorder n/a 1716 1719
disorder n/a 1725 1727
disorder n/a 1729 1732
disorder n/a 1734 1748
disorder n/a 1758 1760
disorder n/a 1762 1765
disorder n/a 1768 1789
disorder n/a 1804 2093
disorder n/a 2101 2124
disorder n/a 2129 2171
low_complexity n/a 2138 2151
low_complexity n/a 2158 2172
disorder n/a 2173 2221
disorder n/a 2224 2266
disorder n/a 2268 2271
disorder n/a 2282 2286
disorder n/a 2291 2296
disorder n/a 2344 2348
disorder n/a 2356 2366
low_complexity n/a 2368 2382
disorder n/a 2371 2385
low_complexity n/a 2387 2398
disorder n/a 2392 2398
disorder n/a 2403 2486
disorder n/a 2488 2489
disorder n/a 2493 2497
disorder n/a 2508 2565
disorder n/a 2567 2568
Pfam PDZ 2623 2697
disorder n/a 2635 2638
disorder n/a 2654 2655
disorder n/a 2707 2729
Pfam PDZ 2751 2833
low_complexity n/a 2756 2769
low_complexity n/a 2784 2799

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O15018. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPITQDNAVL HLPLLYQWLQ NSLQEGGDGP EQRLCQAAIQ KLQEYIQLNF
50
51
AVDESTVPPD HSPPEMEICT VYLTKELGDT ETVGLSFGNI PVFGDYGEKR
100
101
RGGKKRKTHQ GPVLDVGCIW VTELRKNSPA GKSGKVRLRD EILSLNGQLM
150
151
VGVDVSGASY LAEQCWNGGF IYLIMLRRFK HKAHSTYNGN SSNSSEPGET
200
201
PTLELGDRTA KKGKRTRKFG VISRPPANKA PEESKGSAGC EVSSDPSTEL
250
251
ENGPDPELGN GHVFQLENGP DSLKEVAGPH LERSEVDRGT EHRIPKTDAP
300
301
LTTSNDKRRF SKGGKTDFQS SDCLAREEVG RIWKMELLKE SDGLGIQVSG
350
351
GRGSKRSPHA IVVTQVKEGG AAHRDGRLSL GDELLVINGH LLVGLSHEEA
400
401
VAILRSATGM VQLVVASKEN SAEDLLRLTS KSLPDLTSSV EDVSSWTDNE
450
451
DQEADGEEDE GTSSSVQRAM PGTDEPQDVC GAEESKGNLE SPKQGSNKIK
500
501
LKSRLSGGVH RLESVEEYNE LMVRNGDPRI RMLEVSRDGR KHSLPQLLDS
550
551
SSASQEYHIV KKSTRSLSTT QVESPWRLIR PSVISIIGLY KEKGKGLGFS
600
601
IAGGRDCIRG QMGIFVKTIF PNGSAAEDGR LKEGDEILDV NGIPIKGLTF
650
651
QEAIHTFKQI RSGLFVLTVR TKLVSPSLTP CSTPTHMSRS ASPNFNTSGG
700
701
ASAGGSDEGS SSSLGRKTPG PKDRIVMEVT LNKEPRVGLG IGACCLALEN
750
751
SPPGIYIHSL APGSVAKMES NLSRGDQILE VNSVNVRHAA LSKVHAILSK
800
801
CPPGPVRLVI GRHPNPKVSE QEMDEVIARS TYQESKEANS SPGLGTPLKS
850
851
PSLAKKDSLI SESELSQYFA HDVPGPLSDF MVAGSEDEDH PGSGCSTSEE
900
901
GSLPPSTSTH KEPGKPRANS LVTLGSHRAS GLFHKQVTVA RQASLPGSPQ
950
951
ALRNPLLRQR KVGCYDANDA SDEEEFDREG DCISLPGALP GPIRPLSEDD
1000
1001
PRRVSISSSK GMDVHNQEER PRKTLVSKAI SAPLLGSSVD LEESIPEGMV
1050
1051
DAASYAANLT DSAEAPKGSP GSWWKKELSG SSSAPKLEYT VRTDTQSPTN
1100
1101
TGSPSSPQQK SEGLGSRHRP VARVSPHCKR SEAEAKPSGS QTVNLTGRAN
1150
1151
DPCDLDSRVQ ATSVKVTVAG FQPGGAVEKE SLGKLTTGDA CVSTSCELAS
1200
1201
ALSHLDASHL TENLPKAASE LGQQPMTELD SSSDLISSPG KKGAAHPDPS
1250
1251
KTSVDTGQVS RPENPSQPAS PRVTKCKARS PVRLPHEGSP SPGEKAAAPP
1300
1301
DYSKTRSASE TSTPHNTRRV AALRGAGPGA EGMTPAGAVL PGDPLTSQEQ
1350
1351
RQGAPGNHSK ALEMTGIHAP ESSQEPSLLE GADSVSSRAP QASLSMLPST
1400
1401
DNTKEACGHV SGHCCPGGSR ESPVTDIDSF IKELDASAAR SPSSQTGDSG
1450
1451
SQEGSAQGHP PAGAGGGSSC RAEPVPGGQT SSPRRAWAAG APAYPQWASQ
1500
1501
PSVLDSINPD KHFTVNKNFL SNYSRNFSSF HEDSTSLSGL GDSTEPSLSS
1550
1551
MYGDAEDSSS DPESLTEAPR ASARDGWSPP RSRVSLHKED PSESEEEQIE
1600
1601
ICSTRGCPNP PSSPAHLPTQ AAICPASAKV LSLKYSTPRE SVASPREKAA
1650
1651
CLPGSYTSGP DSSQPSSLLE MSSQEHETHA DISTSQNHRP SCAEETTEVT
1700
1701
SASSAMENSP LSKVARHFHS PPIILSSPNM VNGLEHDLLD DETLNQYETS
1750
1751
INAAASLSSF SVDVPKNGES VLENLHISES QDLDDLLQKP KMIARRPIMA
1800
1801
WFKEINKHNQ GTHLRSKTEK EQPLMPARSP DSKIQMVSSS QKKGVTVPHS
1850
1851
PPQPKTNLEN KDLSKKSPAE MLLTNGQKAK CGPKLKRLSL KGKAKVNSEA
1900
1901
PAANAVKAGG TDHRKPLISP QTSHKTLSKA VSQRLHVADH EDPDRNTTAA
1950
1951
PRSPQCVLES KPPLATSGPL KPSVSDTSIR TFVSPLTSPK PVPEQGMWSR
2000
2001
FHMAVLSEPD RGCPTTPKSP KCRAEGRAPR ADSGPVSPAA SRNGMSVAGN
2050
2051
RQSEPRLASH VAADTAQPRP TGEKGGNIMA SDRLERTNQL KIVEISAEAV
2100
2101
SETVCGNKPA ESDRRGGCLA QGNCQEKSEI RLYRQVAESS TSHPSSLPSH
2150
2151
ASQAEQEMSR SFSMAKLASS SSSLQTAIRK AEYSQGKSSL MSDSRGVPRN
2200
2201
SIPGGPSGED HLYFTPRPAT RTYSMPAQFS SHFGREGHPP HSLGRSRDSQ
2250
2251
VPVTSSVVPE AKASRGGLPS LANGQGIYSV KPLLDTSRNL PATDEGDIIS
2300
2301
VQETSCLVTD KIKVTRRHYC YEQNWPHEST SFFSVKQRIK SFENLANADR
2350
2351
PVAKSGASPF LSVSSKPPIG RRSSGSIVSG SLGHPGDAAA RLLRRSLSSC
2400
2401
SENQSEAGTL LPQMAKSPSI MTLTISRQNP PETSSKGSDS ELKKSLGPLG
2450
2451
IPTPTMTLAS PVKRNKSSVR HTQPSPVSRS KLQELRALSM PDLDKLCSED
2500
2501
YSAGPSAVLF KTELEITPRR SPGPPAGGVS CPEKGGNRAC PGGSGPKTSA
2550
2551
AETPSSASDT GEAAQDLPFR RSWSVNLDQL LVSAGDQQRL QSVLSSVGSK
2600
2601
STILTLIQEA KAQSENEEDV CFIVLNRKEG SGLGFSVAGG TDVEPKSITV
2650
2651
HRVFSQGAAS QEGTMNRGDF LLSVNGASLA GLAHGNVLKV LHQAQLHKDA
2700
2701
LVVIKKGMDQ PRPSARQEPP TANGKGLLSR KTIPLEPGIG RSVAVHDALC
2750
2751
VEVLKTSAGL GLSLDGGKSS VTGDGPLVIK RVYKGGAAEQ AGIIEAGDEI
2800
2801
LAINGKPLVG LMHFDAWNIM KSVPEGPVQL LIRKHRNSS            
2839
 

Show the unformatted sequence.

Checksums:
CRC64:4B1CB91A9CE96267
MD5:216cffedd86b84a8c5b696dc65474687

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.