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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PUR4_HUMAN (O15067)

Summary

This is the summary of UniProt entry PUR4_HUMAN (O15067).

Description: Phosphoribosylformylglycinamidine synthase EC=6.3.5.3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1338 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 18 29
Pfam FGAR-AT_N 39 160
disorder n/a 141 142
disorder n/a 153 165
disorder n/a 169 170
disorder n/a 172 173
Pfam FGAR-AT_linker 184 232
disorder n/a 217 222
disorder n/a 252 254
disorder n/a 281 283
disorder n/a 285 299
disorder n/a 317 319
disorder n/a 331 332
disorder n/a 435 445
Pfam AIRS_C 444 603
low_complexity n/a 451 463
low_complexity n/a 459 472
disorder n/a 476 487
disorder n/a 495 499
disorder n/a 513 517
disorder n/a 522 525
disorder n/a 607 621
low_complexity n/a 786 798
Pfam AIRS_C 848 991
disorder n/a 1030 1032
disorder n/a 1047 1071
Pfam GATase_5 1062 1333
disorder n/a 1175 1187
disorder n/a 1189 1190
disorder n/a 1256 1258
disorder n/a 1260 1275

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O15067. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSPVLHFYVR PSGHEGAAPG HTRRKLQGKL PELQGVETEL CYNVNWTAEA
50
51
LPSAEETKKL MWLFGCPLLL DDVARESWLL PGSNDLLLEV GPRLNFSTPT
100
101
STNIVSVCRA TGLGPVDRVE TTRRYRLSFA HPPSAEVEAI ALATLHDRMT
150
151
EQHFPHPIQS FSPESMPEPL NGPINILGEG RLALEKANQE LGLALDSWDL
200
201
DFYTKRFQEL QRNPSTVEAF DLAQSNSEHS RHWFFKGQLH VDGQKLVHSL
250
251
FESIMSTQES SNPNNVLKFC DNSSAIQGKE VRFLRPEDPT RPSRFQQQQG
300
301
LRHVVFTAET HNFPTGVCPF SGATTGTGGR IRDVQCTGRG AHVVAGTAGY
350
351
CFGNLHIPGY NLPWEDPSFQ YPGNFARPLE VAIEASNGAS DYGNKFGEPV
400
401
LAGFARSLGL QLPDGQRREW IKPIMFSGGI GSMEADHISK EAPEPGMEVV
450
451
KVGGPVYRIG VGGGAASSVQ VQGDNTSDLD FGAVQRGDPE MEQKMNRVIR
500
501
ACVEAPKGNP ICSLHDQGAG GNGNVLKELS DPAGAIIYTS RFQLGDPTLN
550
551
ALEIWGAEYQ ESNALLLRSP NRDFLTHVSA RERCPACFVG TITGDRRIVL
600
601
VDDRECPVRR NGQGDAPPTP LPTPVDLELE WVLGKMPRKE FFLQRKPPML
650
651
QPLALPPGLS VHQALERVLR LPAVASKRYL TNKVDRSVGG LVAQQQCVGP
700
701
LQTPLADVAV VALSHEELIG AATALGEQPV KSLLDPKVAA RLAVAEALTN
750
751
LVFALVTDLR DVKCSGNWMW AAKLPGEGAA LADACEAMVA VMAALGVAVD
800
801
GGKDSLSMAA RVGTETVRAP GSLVISAYAV CPDITATVTP DLKHPEGRGH
850
851
LLYVALSPGQ HRLGGTALAQ CFSQLGEHPP DLDLPENLVR AFSITQGLLK
900
901
DRLLCSGHDV SDGGLVTCLL EMAFAGNCGL QVDVPVPRVD VLSVLFAEEP
950
951
GLVLEVQEPD LAQVLKRYRD AGLHCLELGH TGEAGPHAMV RVSVNGAVVL
1000
1001
EEPVGELRAL WEETSFQLDR LQAEPRCVAE EERGLRERMG PSYCLPPTFP
1050
1051
KASVPREPGG PSPRVAILRE EGSNGDREMA DAFHLAGFEV WDVTMQDLCS
1100
1101
GAIGLDTFRG VAFVGGFSYA DVLGSAKGWA AAVTFHPRAG AELRRFRKRP
1150
1151
DTFSLGVCNG CQLLALLGWV GGDPNEDAAE MGPDSQPARP GLLLRHNLSG
1200
1201
RYESRWASVR VGPGPALMLR GMEGAVLPVW SAHGEGYVAF SSPELQAQIE
1250
1251
ARGLAPLHWA DDDGNPTEQY PLNPNGSPGG VAGICSCDGR HLAVMPHPER
1300
1301
AVRPWQWAWR PPPFDTLTTS PWLQLFINAR NWTLEGSC             
1338
 

Show the unformatted sequence.

Checksums:
CRC64:273405025B701DAF
MD5:2224c5c70dba025928b500c84dc5e478

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.