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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CE290_HUMAN (O15078)

Summary

This is the summary of UniProt entry CE290_HUMAN (O15078).

Description: Centrosomal protein of 290 kDa
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 2479 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 5 6
disorder n/a 8 13
coiled_coil n/a 59 104
low_complexity n/a 62 81
disorder n/a 69 71
disorder n/a 74 75
disorder n/a 81 82
disorder n/a 84 86
disorder n/a 94 106
coiled_coil n/a 117 193
low_complexity n/a 127 143
disorder n/a 128 168
low_complexity n/a 145 159
low_complexity n/a 161 174
disorder n/a 191 203
coiled_coil n/a 215 298
disorder n/a 229 252
disorder n/a 254 259
disorder n/a 268 269
disorder n/a 275 276
disorder n/a 286 290
coiled_coil n/a 317 351
disorder n/a 338 339
disorder n/a 349 352
disorder n/a 354 355
coiled_coil n/a 357 391
disorder n/a 368 371
disorder n/a 395 397
disorder n/a 399 401
coiled_coil n/a 413 447
low_complexity n/a 416 436
disorder n/a 424 433
coiled_coil n/a 465 506
coiled_coil n/a 528 565
low_complexity n/a 538 552
disorder n/a 560 584
coiled_coil n/a 602 664
disorder n/a 610 611
disorder n/a 652 656
disorder n/a 658 663
disorder n/a 666 667
disorder n/a 669 670
coiled_coil n/a 698 753
disorder n/a 712 717
disorder n/a 719 721
coiled_coil n/a 781 818
low_complexity n/a 787 802
disorder n/a 799 800
coiled_coil n/a 830 878
disorder n/a 838 839
coiled_coil n/a 896 927
coiled_coil n/a 962 982
coiled_coil n/a 993 1027
disorder n/a 1027 1029
disorder n/a 1032 1043
disorder n/a 1045 1046
disorder n/a 1066 1068
disorder n/a 1070 1071
disorder n/a 1073 1075
coiled_coil n/a 1073 1107
disorder n/a 1078 1083
disorder n/a 1125 1126
coiled_coil n/a 1138 1158
coiled_coil n/a 1221 1248
Pfam CEP209_CC5 1289 1416
coiled_coil n/a 1290 1331
disorder n/a 1301 1319
low_complexity n/a 1317 1331
coiled_coil n/a 1349 1399
disorder n/a 1432 1435
disorder n/a 1439 1443
coiled_coil n/a 1467 1494
low_complexity n/a 1475 1492
disorder n/a 1518 1526
disorder n/a 1529 1543
coiled_coil n/a 1535 1580
disorder n/a 1574 1576
disorder n/a 1601 1602
disorder n/a 1604 1611
disorder n/a 1615 1625
low_complexity n/a 1633 1651
coiled_coil n/a 1641 1714
low_complexity n/a 1679 1688
disorder n/a 1704 1729
coiled_coil n/a 1727 1761
low_complexity n/a 1743 1754
disorder n/a 1760 1767
disorder n/a 1774 1782
coiled_coil n/a 1784 1860
disorder n/a 1785 1787
disorder n/a 1791 1793
low_complexity n/a 1794 1806
disorder n/a 1799 1826
low_complexity n/a 1812 1826
disorder n/a 1830 1831
disorder n/a 1837 1839
disorder n/a 1848 1849
disorder n/a 1854 1862
coiled_coil n/a 1867 1894
disorder n/a 1868 1869
disorder n/a 1892 1899
coiled_coil n/a 1915 1935
coiled_coil n/a 1977 1999
low_complexity n/a 1980 1997
coiled_coil n/a 2015 2035
disorder n/a 2047 2063
coiled_coil n/a 2072 2113
disorder n/a 2113 2129
coiled_coil n/a 2134 2161
disorder n/a 2151 2165
coiled_coil n/a 2163 2183
disorder n/a 2168 2172
low_complexity n/a 2169 2184
disorder n/a 2175 2180
disorder n/a 2184 2193
disorder n/a 2195 2197
disorder n/a 2199 2201
coiled_coil n/a 2199 2254
disorder n/a 2203 2211
low_complexity n/a 2207 2216
disorder n/a 2213 2218
disorder n/a 2244 2257
coiled_coil n/a 2272 2320
disorder n/a 2297 2301
disorder n/a 2304 2305
disorder n/a 2307 2312
disorder n/a 2323 2325
disorder n/a 2328 2329
coiled_coil n/a 2334 2368
disorder n/a 2338 2339
disorder n/a 2357 2382
coiled_coil n/a 2378 2412
low_complexity n/a 2397 2414
coiled_coil n/a 2431 2451
disorder n/a 2459 2468
low_complexity n/a 2464 2471

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O15078. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPPNINWKEI MKVDPDDLPR QEELADNLLI SLSKVEVNEL KSEKQENVIH
50
51
LFRITQSLMK MKAQEVELAL EEVEKAGEEQ AKFENQLKTK VMKLENELEM
100
101
AQQSAGGRDT RFLRNEICQL EKQLEQKDRE LEDMEKELEK EKKVNEQLAL
150
151
RNEEAENENS KLRRENKRLK KKNEQLCQDI IDYQKQIDSQ KETLLSRRGE
200
201
DSDYRSQLSK KNYELIQYLD EIQTLTEANE KIEVQNQEMR KNLEESVQEM
250
251
EKMTDEYNRM KAIVHQTDNV IDQLKKENDH YQLQVQELTD LLKSKNEEDD
300
301
PIMVAVNAKV EEWKLILSSK DDEIIEYQQM LHNLREKLKN AQLDADKSNV
350
351
MALQQGIQER DSQIKMLTEQ VEQYTKEMEK NTCIIEDLKN ELQRNKGAST
400
401
LSQQTHMKIQ STLDILKEKT KEAERTAELA EADAREKDKE LVEALKRLKD
450
451
YESGVYGLED AVVEIKNCKN QIKIRDREIE ILTKEINKLE LKISDFLDEN
500
501
EALRERVGLE PKTMIDLTEF RNSKHLKQQQ YRAENQILLK EIESLEEERL
550
551
DLKKKIRQMA QERGKRSATS GLTTEDLNLT ENISQGDRIS ERKLDLLSLK
600
601
NMSEAQSKNE FLSRELIEKE RDLERSRTVI AKFQNKLKEL VEENKQLEEG
650
651
MKEILQAIKE MQKDPDVKGG ETSLIIPSLE RLVNAIESKN AEGIFDASLH
700
701
LKAQVDQLTG RNEELRQELR ESRKEAINYS QQLAKANLKI DHLEKETSLL
750
751
RQSEGSNVVF KGIDLPDGIA PSSASIINSQ NEYLIHLLQE LENKEKKLKN
800
801
LEDSLEDYNR KFAVIRHQQS LLYKEYLSEK ETWKTESKTI KEEKRKLEDQ
850
851
VQQDAIKVKE YNNLLNALQM DSDEMKKILA ENSRKITVLQ VNEKSLIRQY
900
901
TTLVELERQL RKENEKQKNE LLSMEAEVCE KIGCLQRFKE MAIFKIAALQ
950
951
KVVDNSVSLS ELELANKQYN ELTAKYRDIL QKDNMLVQRT SNLEHLECEN
1000
1001
ISLKEQVESI NKELEITKEK LHTIEQAWEQ ETKLGNESSM DKAKKSITNS
1050
1051
DIVSISKKIT MLEMKELNER QRAEHCQKMY EHLRTSLKQM EERNFELETK
1100
1101
FAELTKINLD AQKVEQMLRD ELADSVSKAV SDADRQRILE LEKNEMELKV
1150
1151
EVSKLREISD IARRQVEILN AQQQSRDKEV ESLRMQLLDY QAQSDEKSLI
1200
1201
AKLHQHNVSL QLSEATALGK LESITSKLQK MEAYNLRLEQ KLDEKEQALY
1250
1251
YARLEGRNRA KHLRQTIQSL RRQFSGALPL AQQEKFSKTM IQLQNDKLKI
1300
1301
MQEMKNSQQE HRNMENKTLE MELKLKGLEE LISTLKDTKG AQKVINWHMK
1350
1351
IEELRLQELK LNRELVKDKE EIKYLNNIIS EYERTISSLE EEIVQQNKFH
1400
1401
EERQMAWDQR EVDLERQLDI FDRQQNEILN AAQKFEEATG SIPDPSLPLP
1450
1451
NQLEIALRKI KENIRIILET RATCKSLEEK LKEKESALRL AEQNILSRDK
1500
1501
VINELRLRLP ATAEREKLIA ELGRKEMEPK SHHTLKIAHQ TIANMQARLN
1550
1551
QKEEVLKKYQ RLLEKAREEQ REIVKKHEED LHILHHRLEL QADSSLNKFK
1600
1601
QTAWDLMKQS PTPVPTNKHF IRLAEMEQTV AEQDDSLSSL LVKLKKVSQD
1650
1651
LERQREITEL KVKEFENIKL QLQENHEDEV KKVKAEVEDL KYLLDQSQKE
1700
1701
SQCLKSELQA QKEANSRAPT TTMRNLVERL KSQLALKEKQ QKALSRALLE
1750
1751
LRAEMTAAAE ERIISATSQK EAHLNVQQIV DRHTRELKTQ VEDLNENLLK
1800
1801
LKEALKTSKN RENSLTDNLN DLNNELQKKQ KAYNKILREK EEIDQENDEL
1850
1851
KRQIKRLTSG LQGKPLTDNK QSLIEELQRK VKKLENQLEG KVEEVDLKPM
1900
1901
KEKNAKEELI RWEEGKKWQA KIEGIRNKLK EKEGEVFTLT KQLNTLKDLF
1950
1951
AKADKEKLTL QRKLKTTGMT VDQVLGIRAL ESEKELEELK KRNLDLENDI
2000
2001
LYMRAHQALP RDSVVEDLHL QNRYLQEKLH ALEKQFSKDT YSKPSISGIE
2050
2051
SDDHCQREQE LQKENLKLSS ENIELKFQLE QANKDLPRLK NQVRDLKEMC
2100
2101
EFLKKEKAEV QRKLGHVRGS GRSGKTIPEL EKTIGLMKKV VEKVQRENEQ
2150
2151
LKKASGILTS EKMANIEQEN EKLKAELEKL KAHLGHQLSM HYESKTKGTE
2200
2201
KIIAENERLR KELKKETDAA EKLRIAKNNL EILNEKMTVQ LEETGKRLQF
2250
2251
AESRGPQLEG ADSKSWKSIV VTRMYETKLK ELETDIAKKN QSITDLKQLV
2300
2301
KEATEREQKV NKYNEDLEQQ IKILKHVPEG AETEQGLKRE LQVLRLANHQ
2350
2351
LDKEKAELIH QIEANKDQSG AESTIPDADQ LKEKIKDLET QLKMSDLEKQ
2400
2401
HLKEEIKKLK KELENFDPSF FEEIEDLKYN YKEEVKKNIL LEEKVKKLSE
2450
2451
QLGVELTSPV AASEEFEDEE ESPVNFPIY                       
2479
 

Show the unformatted sequence.

Checksums:
CRC64:7CA87D53FAF036FC
MD5:b99d5f454e627e40999dca6504b8c938

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.