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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CHAD_HUMAN (O15335)

Summary

This is the summary of UniProt entry CHAD_HUMAN (O15335).

Description: Chondroadherin
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 359 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 21
low_complexity n/a 5 21
Pfam LRRNT 22 50
Pfam LRR_8 75 135
low_complexity n/a 119 130
Pfam LRR_8 147 207
Pfam LRR_8 244 301
disorder n/a 354 359

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O15335. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVRPMLLLSL GLLAGLLPAL AACPQNCHCH SDLQHVICDK VGLQKIPKVS
50
51
EKTKLLNLQR NNFPVLAANS FRAMPNLVSL HLQHCQIREV AAGAFRGLKQ
100
101
LIYLYLSHND IRVLRAGAFD DLTELTYLYL DHNKVTELPR GLLSPLVNLF
150
151
ILQLNNNKIR ELRAGAFQGA KDLRWLYLSE NALSSLQPGA LDDVENLAKF
200
201
HVDRNQLSSY PSAALSKLRV VEELKLSHNP LKSIPDNAFQ SFGRYLETLW
250
251
LDNTNLEKFS DGAFLGVTTL KHVHLENNRL NQLPSNFPFD SLETLALTNN
300
301
PWKCTCQLRG LRRWLEAKAS RPDATCASPA KFKGQHIRDT DAFRSCKFPT
350
351
KRSKKAGRH                                             
359
 

Show the unformatted sequence.

Checksums:
CRC64:CF24D2B5A5DFCF0C
MD5:c7cf2df3d3d8e0489d3c9a960af36f32

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
LRR_8 147 - 207 5LFN A 147 - 207 Jmol OpenAstexViewer
B 147 - 207 Jmol OpenAstexViewer
C 147 - 207 Jmol OpenAstexViewer
D 147 - 207 Jmol OpenAstexViewer
5MX1 A 147 - 207 Jmol OpenAstexViewer
B 147 - 207 Jmol OpenAstexViewer
244 - 301 5LFN A 244 - 301 Jmol OpenAstexViewer
B 244 - 301 Jmol OpenAstexViewer
C 244 - 301 Jmol OpenAstexViewer
D 244 - 301 Jmol OpenAstexViewer
5MX1 A 244 - 301 Jmol OpenAstexViewer
B 244 - 301 Jmol OpenAstexViewer
75 - 135 5LFN A 75 - 135 Jmol OpenAstexViewer
B 75 - 135 Jmol OpenAstexViewer
C 75 - 135 Jmol OpenAstexViewer
D 75 - 135 Jmol OpenAstexViewer
5MX1 A 75 - 135 Jmol OpenAstexViewer
B 75 - 135 Jmol OpenAstexViewer
LRRNT 22 - 50 5MX1 A 22 - 50 Jmol OpenAstexViewer
B 22 - 50 Jmol OpenAstexViewer
23 - 50 5LFN A 23 - 50 Jmol OpenAstexViewer
B 23 - 50 Jmol OpenAstexViewer
C 23 - 50 Jmol OpenAstexViewer
D 23 - 50 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.