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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TET3_HUMAN (O43151)

Summary

This is the summary of UniProt entry TET3_HUMAN (O43151).

Description: Methylcytosine dioxygenase TET3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1660 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 63
low_complexity n/a 65 76
disorder n/a 89 127
low_complexity n/a 116 127
disorder n/a 129 139
disorder n/a 159 211
low_complexity n/a 160 182
disorder n/a 222 223
disorder n/a 228 262
disorder n/a 264 623
low_complexity n/a 279 293
low_complexity n/a 310 324
low_complexity n/a 358 369
low_complexity n/a 413 439
low_complexity n/a 432 447
disorder n/a 633 659
disorder n/a 675 677
disorder n/a 680 683
Pfam Tet_JBP 850 1562
disorder n/a 872 874
disorder n/a 989 995
disorder n/a 1019 1029
low_complexity n/a 1024 1044
coiled_coil n/a 1026 1046
disorder n/a 1035 1047
low_complexity n/a 1066 1079
disorder n/a 1070 1071
disorder n/a 1081 1082
disorder n/a 1176 1177
disorder n/a 1182 1185
disorder n/a 1204 1231
low_complexity n/a 1210 1224
disorder n/a 1236 1238
disorder n/a 1243 1245
disorder n/a 1251 1321
low_complexity n/a 1315 1328
disorder n/a 1323 1325
disorder n/a 1355 1378
disorder n/a 1386 1389
disorder n/a 1394 1395
disorder n/a 1402 1405
disorder n/a 1407 1409
disorder n/a 1415 1437
disorder n/a 1469 1509
low_complexity n/a 1483 1501
disorder n/a 1515 1516
disorder n/a 1540 1546
disorder n/a 1569 1570
coiled_coil n/a 1571 1591
disorder n/a 1575 1576
low_complexity n/a 1579 1594
disorder n/a 1587 1593
disorder n/a 1598 1599
disorder n/a 1615 1624
disorder n/a 1626 1632

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O43151. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDSGPVYHGD SRQLSASGVP VNGAREPAGP SLLGTGGPWR VDQKPDWEAA
50
51
PGPAHTARLE DAHDLVAFSA VAEAVSSYGA LSTRLYETFN REMSREAGNN
100
101
SRGPRPGPEG CSAGSEDLDT LQTALALARH GMKPPNCNCD GPECPDYLEW
150
151
LEGKIKSVVM EGGEERPRLP GPLPPGEAGL PAPSTRPLLS SEVPQISPQE
200
201
GLPLSQSALS IAKEKNISLQ TAIAIEALTQ LSSALPQPSH STPQASCPLP
250
251
EALSPPAPFR SPQSYLRAPS WPVVPPEEHS SFAPDSSAFP PATPRTEFPE
300
301
AWGTDTPPAT PRSSWPMPRP SPDPMAELEQ LLGSASDYIQ SVFKRPEALP
350
351
TKPKVKVEAP SSSPAPAPSP VLQREAPTPS SEPDTHQKAQ TALQQHLHHK
400
401
RSLFLEQVHD TSFPAPSEPS APGWWPPPSS PVPRLPDRPP KEKKKKLPTP
450
451
AGGPVGTEKA APGIKPSVRK PIQIKKSRPR EAQPLFPPVR QIVLEGLRSP
500
501
ASQEVQAHPP APLPASQGSA VPLPPEPSLA LFAPSPSRDS LLPPTQEMRS
550
551
PSPMTALQPG STGPLPPADD KLEELIRQFE AEFGDSFGLP GPPSVPIQDP
600
601
ENQQTCLPAP ESPFATRSPK QIKIESSGAV TVLSTTCFHS EEGGQEATPT
650
651
KAENPLTPTL SGFLESPLKY LDTPTKSLLD TPAKRAQAEF PTCDCVEQIV
700
701
EKDEGPYYTH LGSGPTVASI RELMEERYGE KGKAIRIEKV IYTGKEGKSS
750
751
RGCPIAKWVI RRHTLEEKLL CLVRHRAGHH CQNAVIVILI LAWEGIPRSL
800
801
GDTLYQELTD TLRKYGNPTS RRCGLNDDRT CACQGKDPNT CGASFSFGCS
850
851
WSMYFNGCKY ARSKTPRKFR LAGDNPKEEE VLRKSFQDLA TEVAPLYKRL
900
901
APQAYQNQVT NEEIAIDCRL GLKEGRPFAG VTACMDFCAH AHKDQHNLYN
950
951
GCTVVCTLTK EDNRCVGKIP EDEQLHVLPL YKMANTDEFG SEENQNAKVG
1000
1001
SGAIQVLTAF PREVRRLPEP AKSCRQRQLE ARKAAAEKKK IQKEKLSTPE
1050
1051
KIKQEALELA GITSDPGLSL KGGLSQQGLK PSLKVEPQNH FSSFKYSGNA
1100
1101
VVESYSVLGN CRPSDPYSMN SVYSYHSYYA QPSLTSVNGF HSKYALPSFS
1150
1151
YYGFPSSNPV FPSQFLGPGA WGHSGSSGSF EKKPDLHALH NSLSPAYGGA
1200
1201
EFAELPSQAV PTDAHHPTPH HQQPAYPGPK EYLLPKAPLL HSVSRDPSPF
1250
1251
AQSSNCYNRS IKQEPVDPLT QAEPVPRDAG KMGKTPLSEV SQNGGPSHLW
1300
1301
GQYSGGPSMS PKRTNGVGGS WGVFSSGESP AIVPDKLSSF GASCLAPSHF
1350
1351
TDGQWGLFPG EGQQAASHSG GRLRGKPWSP CKFGNSTSAL AGPSLTEKPW
1400
1401
ALGAGDFNSA LKGSPGFQDK LWNPMKGEEG RIPAAGASQL DRAWQSFGLP
1450
1451
LGSSEKLFGA LKSEEKLWDP FSLEEGPAEE PPSKGAVKEE KGGGGAEEEE
1500
1501
EELWSDSEHN FLDENIGGVA VAPAHGSILI ECARRELHAT TPLKKPNRCH
1550
1551
PTRISLVFYQ HKNLNQPNHG LALWEAKMKQ LAERARARQE EAARLGLGQQ
1600
1601
EAKLYGKKRK WGGTVVAEPQ QKEKKGVVPT RQALAVPTDS AVTVSSYAYT
1650
1651
KVTGPYSRWI                                            
1660
 

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Checksums:
CRC64:181024BFAC9B54D2
MD5:0bd83fd1eb96a095c298d58a15280497

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.