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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GPR39_HUMAN (O43194)

Summary

This is the summary of UniProt entry GPR39_HUMAN (O43194).

Description: G-protein coupled receptor 39
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 453 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
transmembrane n/a 28 51
Pfam 7tm_1 47 344
transmembrane n/a 72 92
transmembrane n/a 112 131
transmembrane n/a 152 174
disorder n/a 192 197
transmembrane n/a 224 246
disorder n/a 260 272
transmembrane n/a 283 301
transmembrane n/a 321 343
disorder n/a 374 375
low_complexity n/a 417 434
disorder n/a 424 453

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O43194. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASPSLPGSD CSQIIDHSHV PEFEVATWIK ITLILVYLII FVMGLLGNSA
50
51
TIRVTQVLQK KGYLQKEVTD HMVSLACSDI LVFLIGMPME FYSIIWNPLT
100
101
TSSYTLSCKL HTFLFEACSY ATLLHVLTLS FERYIAICHP FRYKAVSGPC
150
151
QVKLLIGFVW VTSALVALPL LFAMGTEYPL VNVPSHRGLT CNRSSTRHHE
200
201
QPETSNMSIC TNLSSRWTVF QSSIFGAFVV YLVVLLSVAF MCWNMMQVLM
250
251
KSQKGSLAGG TRPPQLRKSE SEESRTARRQ TIIFLRLIVV TLAVCWMPNQ
300
301
IRRIMAAAKP KHDWTRSYFR AYMILLPFSE TFFYLSSVIN PLLYTVSSQQ
350
351
FRRVFVQVLC CRLSLQHANH EKRLRVHAHS TTDSARFVQR PLLFASRRQS
400
401
SARRTEKIFL STFQSEAEPQ SKSQSLSLES LEPNSGAKPA NSAAENGFQE
450
451
HEV                                                   
453
 

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Checksums:
CRC64:8E3A233420D9021E
MD5:bb77c3788942d148c111a7c4f68f36c6

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.