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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ADCY6_HUMAN (O43306)

Summary

This is the summary of UniProt entry ADCY6_HUMAN (O43306).

Description: Adenylate cyclase type 6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1168 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam AC_N 11 368
disorder n/a 14 34
disorder n/a 49 70
low_complexity n/a 51 63
low_complexity n/a 93 106
disorder n/a 101 107
low_complexity n/a 151 167
transmembrane n/a 152 172
transmembrane n/a 178 198
low_complexity n/a 181 189
transmembrane n/a 210 230
low_complexity n/a 213 229
transmembrane n/a 236 253
transmembrane n/a 260 278
transmembrane n/a 290 310
Pfam Guanylate_cyc 370 553
disorder n/a 537 538
disorder n/a 564 568
Pfam DUF1053 580 669
disorder n/a 601 606
disorder n/a 609 616
transmembrane n/a 669 690
low_complexity n/a 676 690
transmembrane n/a 696 721
transmembrane n/a 742 762
transmembrane n/a 815 833
transmembrane n/a 840 862
low_complexity n/a 843 855
transmembrane n/a 893 911
Pfam Guanylate_cyc 970 1164
disorder n/a 1118 1120

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O43306. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSWFSGLLVP KVDERKTAWG ERNGQKRSRR RGTRAGGFCT PRYMSCLRDA
50
51
EPPSPTPAGP PRCPWQDDAF IRRGGPGKGK ELGLRAVALG FEDTEVTTTA
100
101
GGTAEVAPDA VPRSGRSCWR RLVQVFQSKQ FRSAKLERLY QRYFFQMNQS
150
151
SLTLLMAVLV LLTAVLLAFH AAPARPQPAY VALLACAAAL FVGLMVVCNR
200
201
HSFRQDSMWV VSYVVLGILA AVQVGGALAA DPRSPSAGLW CPVFFVYIAY
250
251
TLLPIRMRAA VLSGLGLSTL HLILAWQLNR GDAFLWKQLG ANVLLFLCTN
300
301
VIGICTHYPA EVSQRQAFQE TRGYIQARLH LQHENRQQER LLLSVLPQHV
350
351
AMEMKEDINT KKEDMMFHKI YIQKHDNVSI LFADIEGFTS LASQCTAQEL
400
401
VMTLNELFAR FDKLAAENHC LRIKILGDCY YCVSGLPEAR ADHAHCCVEM
450
451
GVDMIEAISL VREVTGVNVN MRVGIHSGRV HCGVLGLRKW QFDVWSNDVT
500
501
LANHMEAGGR AGRIHITRAT LQYLNGDYEV EPGRGGERNA YLKEQHIETF
550
551
LILGASQKRK EEKAMLAKLQ RTRANSMEGL MPRWVPDRAF SRTKDSKAFR
600
601
QMGIDDSSKD NRGTQDALNP EDEVDEFLSR AIDARSIDQL RKDHVRRFLL
650
651
TFQREDLEKK YSRKVDPRFG AYVACALLVF CFICFIQLLI FPHSTLMLGI
700
701
YASIFLLLLI TVLICAVYSC GSLFPKALQR LSRSIVRSRA HSTAVGIFSV
750
751
LLVFTSAIAN MFTCNHTPIR SCAARMLNLT PADITACHLQ QLNYSLGLDA
800
801
PLCEGTMPTC SFPEYFIGNM LLSLLASSVF LHISSIGKLA MIFVLGLIYL
850
851
VLLLLGPPAT IFDNYDLLLG VHGLASSNET FDGLDCPAAG RVALKYMTPV
900
901
ILLVFALALY LHAQQVESTA RLDFLWKLQA TGEKEEMEEL QAYNRRLLHN
950
951
ILPKDVAAHF LARERRNDEL YYQSCECVAV MFASIANFSE FYVELEANNE
1000
1001
GVECLRLLNE IIADFDEIIS EERFRQLEKI KTIGSTYMAA SGLNASTYDQ
1050
1051
VGRSHITALA DYAMRLMEQM KHINEHSFNN FQMKIGLNMG PVVAGVIGAR
1100
1101
KPQYDIWGNT VNVSSRMDST GVPDRIQVTT DLYQVLAAKG YQLECRGVVK
1150
1151
VKGKGEMTTY FLNGGPSS                                   
1168
 

Show the unformatted sequence.

Checksums:
CRC64:127BB6E67F73AA61
MD5:409f13cff38ea1bfae700e133e5a939c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.