Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
36  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: B2L11_HUMAN (O43521)

Summary

This is the summary of UniProt entry B2L11_HUMAN (O43521).

Description: Bcl-2-like protein 11
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 198 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 73
Pfam Bim_N 4 40
disorder n/a 75 76
low_complexity n/a 83 93
disorder n/a 100 117
disorder n/a 121 122
Pfam Bclx_interact 130 166
low_complexity n/a 179 193

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O43521. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAKQPSDVSS ECDREGRQLQ PAERPPQLRP GAPTSLQTEP QGNPEGNHGG
50
51
EGDSCPHGSP QGPLAPPASP GPFATRSPLF IFMRRSSLLS RSSSGYFSFD
100
101
TDRSPAPMSC DKSTQTPSPP CQAFNHYLSA MASMRQAEPA DMRPEIWIAQ
150
151
ELRRIGDEFN AYYARRVFLN NYQAAEDHPR MVILRLLRYI VRLVWRMH  
198
 

Show the unformatted sequence.

Checksums:
CRC64:D75735E469CA6997
MD5:2cafede73dbae42bea7f95eca21ef218

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Bclx_interact 141 - 162 2WH6 B 51 - 72 Jmol OpenAstexViewer
141 - 163 2V6Q B 51 - 73 Jmol OpenAstexViewer
141 - 165 2VM6 B 141 - 165 Jmol OpenAstexViewer
5VWV B 141 - 165 Jmol OpenAstexViewer
5VWY B 141 - 165 Jmol OpenAstexViewer
5VX0 B 141 - 165 Jmol OpenAstexViewer
5VX2 D 51 - 75 Jmol OpenAstexViewer
141 - 166 5VWZ B 141 - 166 Jmol OpenAstexViewer
D 141 - 166 Jmol OpenAstexViewer
142 - 162 5VX3 B 84 - 104 Jmol OpenAstexViewer
142 - 164 5VWX B 142 - 164 Jmol OpenAstexViewer
D 142 - 164 Jmol OpenAstexViewer
5VX3 H 84 - 106 Jmol OpenAstexViewer
142 - 165 5VX0 D 142 - 165 Jmol OpenAstexViewer
142 - 166 3FDL B 84 - 108 Jmol OpenAstexViewer
5VWW C 142 - 166 Jmol OpenAstexViewer
143 - 161 3IO8 D 53 - 71 Jmol OpenAstexViewer
5VWW D 143 - 161 Jmol OpenAstexViewer
143 - 163 3KJ1 B 1 - 21 Jmol OpenAstexViewer
3KJ2 B 1 - 21 Jmol OpenAstexViewer
4D2M D 53 - 73 Jmol OpenAstexViewer
143 - 164 4D2M B 53 - 74 Jmol OpenAstexViewer
4ZIE C 143 - 164 Jmol OpenAstexViewer
5VX3 D 85 - 106 Jmol OpenAstexViewer
F 85 - 106 Jmol OpenAstexViewer
143 - 165 2NL9 B 53 - 75 Jmol OpenAstexViewer
3D7V B 53 - 75 Jmol OpenAstexViewer
3IO9 B 53 - 75 Jmol OpenAstexViewer
3KJ0 B 1 - 23 Jmol OpenAstexViewer
5VX2 B 53 - 75 Jmol OpenAstexViewer
143 - 166 4B4S B 53 - 76 Jmol OpenAstexViewer
144 - 159 4ZIF B 144 - 159 Jmol OpenAstexViewer
4ZIH B 144 - 159 Jmol OpenAstexViewer
144 - 164 4QVF B 54 - 74 Jmol OpenAstexViewer
5WOS B 54 - 74 Jmol OpenAstexViewer
144 - 166 3IO8 B 54 - 76 Jmol OpenAstexViewer
145 - 164 2K7W B 145 - 164 Jmol OpenAstexViewer
146 - 163 4A1U B 88 - 105 Jmol OpenAstexViewer
4A1W Q 206 - 223 Jmol OpenAstexViewer
S 206 - 223 Jmol OpenAstexViewer
4UF3 B 56 - 73 Jmol OpenAstexViewer
4YJ4 B 146 - 163 Jmol OpenAstexViewer
146 - 164 5AGW C 1 - 19 Jmol OpenAstexViewer
146 - 166 5AGW D 1 - 21 Jmol OpenAstexViewer
5AGX C 1 - 21 Jmol OpenAstexViewer
D 1 - 21 Jmol OpenAstexViewer
147 - 163 4A1W P 207 - 223 Jmol OpenAstexViewer
R 207 - 223 Jmol OpenAstexViewer
147 - 164 2YQ6 B 147 - 164 Jmol OpenAstexViewer
2YQ7 B 147 - 164 Jmol OpenAstexViewer
148 - 163 5C3G B 90 - 105 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.