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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: XRCC3_HUMAN (O43542)

Summary

This is the summary of UniProt entry XRCC3_HUMAN (O43542).

Description: DNA repair protein XRCC3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 346 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 11 19
Pfam Rad51 52 340
disorder n/a 331 336
disorder n/a 339 346

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O43542. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDLDLLDLNP RIIAAIKKAK LKSVKEVLHF SGPDLKRLTN LSSPEVWHLL
50
51
RTASLHLRGS SILTALQLHQ QKERFPTQHQ RLSLGCPVLD ALLRGGLPLD
100
101
GITELAGRSS AGKTQLALQL CLAVQFPRQH GGLEAGAVYI CTEDAFPHKR
150
151
LQQLMAQQPR LRTDVPGELL QKLRFGSQIF IEHVADVDTL LECVNKKVPV
200
201
LLSRGMARLV VIDSVAAPFR CEFDSQASAP RARHLQSLGA TLRELSSAFQ
250
251
SPVLCINQVT EAMEEQGAAH GPLGFWDERV SPALGITWAN QLLVRLLADR
300
301
LREEEAALGC PARTLRVLSA PHLPPSSCSY TISAEGVRGT PGTQSH    
346
 

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Checksums:
CRC64:4DDF3B163C3B3332
MD5:e214ded1fe845267398b6acc58bd97fb

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.