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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KRT86_HUMAN (O43790)

Summary

This is the summary of UniProt entry KRT86_HUMAN (O43790).

Description: Keratin, type II cuticular Hb6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 486 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Keratin_2_head 2 102
Pfam Filament 105 416
coiled_coil n/a 124 144
coiled_coil n/a 187 207
coiled_coil n/a 215 249
coiled_coil n/a 315 356
coiled_coil n/a 361 395
low_complexity n/a 419 437
low_complexity n/a 441 468

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O43790. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTCGSYCGGR AFSCISACGP RPGRCCITAA PYRGISCYRG LTGGFGSHSV
50
51
CGGFRAGSCG RSFGYRSGGV CGPSPPCITT VSVNESLLTP LNLEIDPNAQ
100
101
CVKQEEKEQI KSLNSRFAAF IDKVRFLEQQ NKLLETKLQF YQNRECCQSN
150
151
LEPLFEGYIE TLRREAECVE ADSGRLASEL NHVQEVLEGY KKKYEEEVSL
200
201
RATAENEFVA LKKDVDCAYL RKSDLEANVE ALIQEIDFLR RLYEEEIRVL
250
251
QSHISDTSVV VKLDNSRDLN MDCIIAEIKA QYDDIVTRSR AEAESWYRSK
300
301
CEEMKATVIR HGETLRRTKE EINELNRMIQ RLTAEVENAK CQNSKLEAAV
350
351
AQSEQQGEAA LSDARCKLAE LEGALQKAKQ DMACLIREYQ EVMNSKLGLD
400
401
IEIATYRRLL EGEEQRLCEG VGSVNVCVSS SRGGVVCGDL CASTTAPVVS
450
451
TRVSSVPSNS NVVVGTTNAC APSARVGVCG GSCKRC               
486
 

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Checksums:
CRC64:5ED86FB4CCA62688
MD5:9f9546443cd8afafbfa3b0be4aed374a

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.