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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: STRN_HUMAN (O43815)

Summary

This is the summary of UniProt entry STRN_HUMAN (O43815).

Description: Striatin
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 780 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 4 15
low_complexity n/a 17 45
disorder n/a 21 26
Pfam Striatin 48 177
coiled_coil n/a 67 115
disorder n/a 120 123
disorder n/a 125 153
disorder n/a 191 194
disorder n/a 196 220
low_complexity n/a 238 254
disorder n/a 245 260
disorder n/a 264 280
disorder n/a 282 317
disorder n/a 328 329
low_complexity n/a 331 348
disorder n/a 333 335
disorder n/a 339 398
low_complexity n/a 376 384
low_complexity n/a 412 429
Pfam WD40 453 491
Pfam WD40 506 544
Pfam WD40 559 597
Pfam WD40 696 734
Pfam WD40 738 779

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O43815. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDEQAGPGVF FSNNHPGAGG AKGLGPLAEA AAAGDGAAAA GAARAQYSLP
50
51
GILHFLQHEW ARFEVERAQW EVERAELQAQ IAFLQGERKG QENLKKDLVR
100
101
RIKMLEYALK QERAKYHKLK YGTELNQGDM KPPSYDSDEG NETEVQPQQN
150
151
SQLMWKQGRQ LLRQYLQEVG YTDTILDVKS KRVRALLGFS SDVTDREDDK
200
201
NQDSVVNGTE AEVKETAMIA KSELTDSASV LDNFKFLESA AADFSDEDED
250
251
DDVDGREKSV IDTSTIVRKK ALPDSGEDRD TKEALKEFDF LVTSEEGDNE
300
301
SRSAGDGTDW EKEDQCLMPE AWNVDQGVIT KLKEQYKKER KGKKGVKRPN
350
351
RSKLQDMLAN LRDVDELPSL QPSVGSPSRP SSSRLPEHEI NRADEVEALT
400
401
FPPSSGKSFI MGADEALESE LGLGELAGLT VANEADSLTY DIANNKDALR
450
451
KTWNPKFTLR SHFDGIRALA FHPIEPVLIT ASEDHTLKMW NLQKTAPAKK
500
501
STSLDVEPIY TFRAHKGPVL CVVMSSNGEQ CYSGGTDGLI QGWNTTNPNI
550
551
DPYDSYDPSV LRGPLLGHTD AVWGLAYSAA HQRLLSCSAD GTLRLWNTTE
600
601
VAPALSVFND TKELGIPASV DLVSSDPSHM VASFSKGYTS IFNMETQQRI
650
651
LTLESNVDTT ANSSCQINRV ISHPTLPISI TAHEDRHIKF YDNNTGKLIH
700
701
SMVAHLEAVT SLAVDPNGLY LMSGSHDCSI RLWNLESKTC IQEFTAHRKK
750
751
FEESIHDVAF HPSKCYIASA GADALAKVFV                      
780
 

Show the unformatted sequence.

Checksums:
CRC64:DDB18A11102BEA35
MD5:dbe90b996ab30f57db080fc2caad48a2

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;