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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: O53347_MYCTU (O53347)

Summary

This is the summary of UniProt entry O53347_MYCTU (O53347).

Description: DNA helicase {ECO:0000256|ARBA:ARBA00012551}
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (NCBI taxonomy ID 83332)
Length: 1101 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam UvrD-helicase 24 337
low_complexity n/a 84 96
low_complexity n/a 128 139
low_complexity n/a 251 262
low_complexity n/a 271 280
disorder n/a 332 335
Pfam UvrD_C 348 513
low_complexity n/a 367 384
disorder n/a 377 379
disorder n/a 391 393
low_complexity n/a 432 447
low_complexity n/a 492 510
disorder n/a 519 524
Pfam UvrD_C 604 772
low_complexity n/a 619 630
disorder n/a 706 708
low_complexity n/a 740 755
disorder n/a 768 775
disorder n/a 778 781
disorder n/a 784 785
disorder n/a 805 815
disorder n/a 817 819
disorder n/a 821 824
low_complexity n/a 847 856
disorder n/a 858 881
low_complexity n/a 882 900
disorder n/a 895 896
Pfam PDDEXK_1 902 1083
disorder n/a 922 924
disorder n/a 967 968
disorder n/a 1024 1031

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O53347. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTQTAAPARY SPAELACALG LFPPTAEQAA VIAAPPGPLV VIAGAGAGKT
50
51
ETMAARVVWL VANGYAEPGQ VLGLTFTRKA AGQLLRRVRS RLARLAGIGL
100
101
GCGDPAACAP VVSTYHAFAG SLLRDYGLLL PLEPDTRLLS ETELWQLAFD
150
151
VVSGYDGVLC TDKSPAAVTS IVVRLWGQLG EHLVDTRALR DTHVELERLV
200
201
HALPAGRYQR DRGPSQWLLR MLATQTQRAE LVPLLDALGE RMHAGKVMDF
250
251
AMQMASAARL AATSPQVGQD LRRRYRVVLL DEYQDTGHAQ RVVLSSLFGG
300
301
GVDDGLALTA VGDPIQSIYG WRGASATNLP RFTTDFPLSD GTPAPVLELL
350
351
TSWRNPPQAL RVANGISAEA RRRSVAVRAL RPRPDAPPGA VRCALLPDVQ
400
401
AEREWIADHL RMRYQRAEAD GVKPPTAAVL VRRNADAAAI ADTLRARGIP
450
451
AEVVGLAGLL SIPEVAEVVA MLRLVADPTA GAAAMRVLTG PRWRLGARDL
500
501
AALWRRALTL SGESPSTASP ESIAMAASAD ADNPCLADAI SDPGSAEGYS
550
551
VAGYGRIGAL AGELSALRGR LGHSLPDLVA EVRRVLGVDC EVRASAPVSG
600
601
GWAGPEHLDA FADVVAGYAE RASARSSEAS VAGLLAYLDV AEVVENGLPP
650
651
AELTVACDRV QVLTVHAAKG LEWQVVAVAH LSRGVFPSTV SRSSWLTDPA
700
701
ELPPLLRGDR ASAGAHGIPV LDTSAVADRK QLSDKISEHR RLLDRRRVDE
750
751
ERRLLYVAVT RAEDTLLVSG HHWGPTGTKP RGPSEFLCEL KDIIDRSAAA
800
801
GDPCGVVEQW ASAPAGDERN PLCDNAIEAV WPADPLAARR GDVERGAALV
850
851
AAAMSADLPG STTDIDHPPR PGDAPWSTDV DALLAERAHA ARGAPARGLP
900
901
NHLSVSSLVE LVGDPVGARQ RLMCRLPKRP DPHAWLGDAF HAWVQQFYGA
950
951
ELLFDLGDLP GAADREVGDP EELAALQRAF TASSWAARTP AAVEVPFEMP
1000
1001
IGDTVVRGRI DAVFVDPDGG ATVVDWKTGK PPHGPAAMRQ AAVQLAVYRL
1050
1051
AWAALRGCPT SSVRTAFYYV RSGITVVPDE LPAPGELAML LTDCAGRRSD
1100
1101
T                                                     
1101
 

Show the unformatted sequence.

Checksums:
CRC64:269C6AAD3657412B
MD5:5f31bd28f33dddb3a002452eaf2b8e18

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;