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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: AT2A2_MOUSE (O55143)

Summary

This is the summary of UniProt entry AT2A2_MOUSE (O55143).

Description: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 EC=3.6.3.8
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 1044 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Cation_ATPase_N 4 72
transmembrane n/a 60 78
transmembrane n/a 84 107
Pfam E1-E2_ATPase 121 329
disorder n/a 191 196
disorder n/a 199 202
disorder n/a 239 240
disorder n/a 247 248
transmembrane n/a 260 280
transmembrane n/a 292 321
Pfam Cation_ATPase 418 527
disorder n/a 498 499
transmembrane n/a 759 782
Pfam Cation_ATPase_C 783 986
transmembrane n/a 833 856
low_complexity n/a 843 860
transmembrane n/a 930 949
transmembrane n/a 955 978
transmembrane n/a 1015 1033

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O55143. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MENAHTKTVE EVLGHFGVNE STGLSLEQVK KLKERWGSNE LPAEEGKTLL
50
51
ELVIEQFEDL LVRILLLAAC ISFVLAWFEE GEETITAFVE PFVILLILVA
100
101
NAIVGVWQER NAENAIEALK EYEPEMGKVY RQDRKSVQRI KAKDIVPGDI
150
151
VEIAVGDKVP ADIRLTSIKS TTLRVDQSIL TGESVSVIKH TDPVPDPRAV
200
201
NQDKKNMLFS GTNIAAGKAM GVVVATGVNT EIGKIRDEMV ATEQERTPLQ
250
251
QKLDEFGEQL SKVISLICIA VWIINIGHFN DPVHGGSWIR GAIYYFKIAV
300
301
ALAVAAIPEG LPAVITTCLA LGTRRMAKKN AIVRSLPSVE TLGCTSVICS
350
351
DKTGTLTTNQ MSVCRMFILD KVEGDTCSLN EFSITGSTYA PIGEVQKDDK
400
401
PVKCHQYDGL VELATICALC NDSALDYNEA KGVYEKVGEA TETALTCLVE
450
451
KMNVFDTELK GLSKIERANA CNSVIKQLMK KEFTLEFSRD RKSMSVYCTP
500
501
NKPSRTSMSK MFVKGAPEGV IDRCTHIRVG STKVPMTPGV KQKIMSVIRE
550
551
WGSGSDTLRC LALATHDNPL KREEMHLEDS ANFIKYETNL TFVGCVGMLD
600
601
PPRIEVASSV KLCRQAGIRV IMITGDNKGT AVAICRRIGI FGQDEDVTSK
650
651
AFTGREFDEL SPSAQRDACL NARCFARVEP SHKSKIVEFL QSFDEITAMT
700
701
GDGVNDAPAL KKSEIGIAMG SGTAVAKTAS EMVLADDNFS TIVAAVEEGR
750
751
AIYNNMKQFI RYLISSNVGE VVCIFLTAAL GFPEALIPVQ LLWVNLVTDG
800
801
LPATALGFNP PDLDIMNKPP RNPKEPLISG WLFFRYLAIG CYVGAATVGA
850
851
AAWWFIAADG GPRVSFYQLS HFLQCKEDNP DFDGVDCAIF ESPYPMTMAL
900
901
SVLVTIEMCN ALNSLSENQS LLRMPPWENI WLVGSICLSM SLHFLILYVE
950
951
PLPLIFQITP LNLTQWLMVL KISLPVILMD ETLKFVARNY LEQPGKECVQ
1000
1001
PATKSSCSLS ACTDGISWPF VLLIMPLVVW VYSTDTNFSD MFWS      
1044
 

Show the unformatted sequence.

Checksums:
CRC64:06A753982116C421
MD5:d73fe365d75a758572c48754e14a5e1f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.