Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: IF2A_PYRHO (O58655)

Summary

This is the summary of UniProt entry IF2A_PYRHO (O58655).

Description: Translation initiation factor 2 subunit alpha
Source organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (NCBI taxonomy ID )
Length: 275 amino acids
Reference Proteome: x

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam S1 8 83
Pfam EIF_2_alpha 121 233

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O58655. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPRKAREYPE EGEFVVATVK RIHNYGAFLE LDEYPGKEAF MHISEVASTW
50
51
VRNIRDYLKE GQKVVAKVIR VDPRKGHIDL SLRRVTQQQR KAKLQEFKRA
100
101
QKAENLLRLA AEKLGKDFEA AWREVWVPLE EEWGEVYAAF EDAAKDGIEV
150
151
LKGHVPDEWL PVLKEIVENY VEVPTVTIDA EFEITVPKPN GVEIIKEALI
200
201
RARDRANKEK DIEVKFTYQG APRYRIDITA PDYYKAEEVL EDIAEEILRV
250
251
IKQAGGEATL LRKEKRIRKV KKRKK                           
275
 

Show the unformatted sequence.

Checksums:
CRC64:6AAAD15F10FFB436
MD5:4815eb0cdbd778e7f78b163d02fe3bf6

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
EIF_2_alpha 121 - 174 3AEV A 121 - 174 Jmol OpenAstexViewer
S1 8 - 83 3AEV A 8 - 83 Jmol OpenAstexViewer