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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NUAK1_HUMAN (O60285)

Summary

This is the summary of UniProt entry NUAK1_HUMAN (O60285).

Description: NUAK family SNF1-like kinase 1 EC=2.7.11.1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 661 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 57
low_complexity n/a 43 54
Pfam Pkinase 55 306
low_complexity n/a 145 156
disorder n/a 267 270
disorder n/a 343 424
disorder n/a 427 429
disorder n/a 432 433
disorder n/a 435 519
low_complexity n/a 474 489
low_complexity n/a 499 509
disorder n/a 527 528
disorder n/a 530 567
low_complexity n/a 562 577
low_complexity n/a 569 588
disorder n/a 583 585
disorder n/a 624 625

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O60285. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEGAAAPVAG DRPDLGLGAP GSPREAVAGA TAALEPRKPH GVKRHHHKHN
50
51
LKHRYELQET LGKGTYGKVK RATERFSGRV VAIKSIRKDK IKDEQDMVHI
100
101
RREIEIMSSL NHPHIISIYE VFENKDKIVI IMEYASKGEL YDYISERRRL
150
151
SERETRHFFR QIVSAVHYCH KNGVVHRDLK LENILLDDNC NIKIADFGLS
200
201
NLYQKDKFLQ TFCGSPLYAS PEIVNGRPYR GPEVDSWALG VLLYTLVYGT
250
251
MPFDGFDHKN LIRQISSGEY REPTQPSDAR GLIRWMLMVN PDRRATIEDI
300
301
ANHWWVNWGY KSSVCDCDAL HDSESPLLAR IIDWHHRSTG LQADTEAKMK
350
351
GLAKPTTSEV MLERQRSLKK SKKENDFAQS GQDAVPESPS KLSSKRPKGI
400
401
LKKRSNSEHR SHSTGFIEGV VGPALPSTFK MEQDLCRTGV LLPSSPEAEV
450
451
PGKLSPKQSA TMPKKGILKK TQQRESGYYS SPERSESSEL LDSNDVMGSS
500
501
IPSPSPPDPA RVTSHSLSCR RKGILKHSSK YSAGTMDPAL VSPEMPTLES
550
551
LSEPGVPAEG LSRSYSRPSS VISDDSVLSS DSFDLLDLQE NRPARQRIRS
600
601
CVSAENFLQI QDFEGLQNRP RPQYLKRYRN RLADSSFSLL TDMDDVTQVY
650
651
KQALEICSKL N                                          
661
 

Show the unformatted sequence.

Checksums:
CRC64:806F37D52CA4718F
MD5:572e4a542b2a0965f318925d94d9bd0d

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.