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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TDRD6_HUMAN (O60522)

Summary

This is the summary of UniProt entry TDRD6_HUMAN (O60522).

Description: Tudor domain-containing protein 6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 2096 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 2
Pfam TUDOR 26 133
low_complexity n/a 170 184
Pfam TUDOR 246 380
disorder n/a 287 291
disorder n/a 294 310
low_complexity n/a 448 468
disorder n/a 452 467
Pfam TUDOR 483 604
disorder n/a 692 694
disorder n/a 696 724
Pfam TUDOR 768 886
Pfam TUDOR 982 1102
disorder n/a 1176 1177
disorder n/a 1249 1250
disorder n/a 1254 1255
disorder n/a 1262 1265
disorder n/a 1268 1269
Pfam TUDOR 1301 1422
Pfam TUDOR 1515 1638
disorder n/a 1754 1756
disorder n/a 1764 1765
disorder n/a 1772 1773
disorder n/a 1779 1781
disorder n/a 1830 1837
disorder n/a 1841 1844
disorder n/a 1846 1848
disorder n/a 1862 1878
disorder n/a 1904 1933
disorder n/a 1957 1963
disorder n/a 1993 2014
disorder n/a 2060 2063
disorder n/a 2074 2082
disorder n/a 2086 2096

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O60522. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MCSTPGMPAP GASLALRVSF VDVHPDVIPV QLWGLVGERR GEYLRLSREI
50
51
QEAAATRGQW ALGSASASPG ELCLVQVGLL WHRCRVVSRQ AQESRVFLLD
100
101
EGRTITAGAG SLAPGRREFF NLPSEVLGCV LAGLVPAGCG AGSGEPPQHW
150
151
PADAVDFLSN LQGKEVHGCV LDVLLLHRLV LLEVPDVFQQ MRELGLARRV
200
201
PDSLFRSLLE RYLTAATASV GSGVPVLSRV PLKQKQPGLD YFYPQLQLGV
250
251
TEAVVITQVC HPHRIHCQLR SVSQEIHRLS ESMAQVYRGS TGTGDENSTS
300
301
ATWEEREESP DKPGSPCASC GLDGHWYRAL LLETFRPQRC AQVLHVDYGR
350
351
KELVSCSSLR YLLPEYFRMP VVTYPCALYG LWDGGRGWSR SQVGDLKTLI
400
401
LGKAVNAKIE FYCSFEHVYY VSLYGEDGIN LNRVFGVQSC CLADRVLQSQ
450
451
ATEEEEPETS QSQSPAEEVD EEISLPALRS IRLKMNAFYD AQVEFVKNPS
500
501
EFWIRLRKHN VTFSKLMRRM CGFYSSASKL DGVVLKPEPD DLCCVKWKEN
550
551
GYYRAIVTKL DDKSVDVFLV DRGNSENVDW YDVRMLLPQF RQLPILAVKC
600
601
TLADIWPLGK TWSQEAVSFF KKTVLHKELV IHILDKQDHQ YVIEILDESR
650
651
TGEENISKVI AQAGYAKYQE FETKENILVN AHSPGHVSNH FTTESNKIPF
700
701
AKTGEGEQKA KRENKTTSVS KALSDTTVVT NGSTELVVQE KVKRASVYFP
750
751
LMQNCLEIKP GSSSKGELEV GSTVEVRVSY VENPGYFWCQ LTRNIQGLKT
800
801
LMSDIQYYCK NTAAPHQRNT LACLAKRTVN RQWSRALISG IQSVEHVNVT
850
851
FVDYGDREMV SVKNIYSISE EFLKVKAQAF RCSLYNLIQP VGQNPFVWDV
900
901
KAIQAFNEFI DNAWQKNLEL KCTIFALASI NEELFNIVDL LTPFQSACHF
950
951
LVEKRLARPV KLQKPLESSV QLHSYFYSTH DMKIGSEELV YITHIDDPWT
1000
1001
FYCQLARNAN ILEQLSCSIT QLSKVLLNLK TSPLNPGTLC LAKYTDGNWY
1050
1051
RGIVIEKEPK KVFFVDFGNI YVVTSDDLLP IPSDAYDVLL LPMQAVRCSL
1100
1101
SDIPDHIPEE VVVWFQETIL DKSLKALVVA KDPDGTLIIE LYGDNIQISA
1150
1151
SINKKLGLLS YKDRIRKKES EVLCSTTETL EEKNENMKLP CTEYLSKSVG
1200
1201
YKLPNKEILE ESYKPQINSS YKELKLLQSL TKTNLVTQYQ DSVGNKNSQV
1250
1251
FPLTTEKKEE ISAETPLKTA RVEATLSERK IGDSCDKDLP LKFCEFPQKT
1300
1301
IMPGFKTTVY VSHINDLSDF YVQLIEDEAE ISHLSERLNS VKTRPEYYVG
1350
1351
PPLQRGDMIC AVFPEDNLWY RAVIKEQQPN DLLSVQFIDY GNVSVVHTNK
1400
1401
IGRLDLVNAI LPGLCIHCSL QGFEVPDNKN SKKMMHYFSQ RTSEAAIRCE
1450
1451
FVKFQDRWEV ILADEHGIIA DDMISRYALS EKSQVELSTQ VIKSASSKSV
1500
1501
NKSDIDTSVF LNWYNPEKKM IRAYATVIDG PEYFWCQFAD TEKLQCLEVE
1550
1551
VQTAGEQVAD RRNCIPCPYI GDPCIVRYRE DGHYYRALIT NICEDYLVSV
1600
1601
RLVDFGNIED CVDPKALWAI PSELLSVPMQ AFPCCLSGFN ISEGLCSQEG
1650
1651
NDYFYEIITE DVLEITILEI RRDVCDIPLA IVDLKSKGKS INEKMEKYSK
1700
1701
TGIKSALPYE NIDSEIKQTL GSYNLDVGLK KLSNKAVQNK IYMEQQTDEL
1750
1751
AEITEKDVNI IGTKPSNFRD PKTDNICEGF ENPCKDKIDT EELEGELECH
1800
1801
LVDKAEFDDK YLITGFNTLL PHANETKEIL ELNSLEVPLS PDDESKEFLE
1850
1851
LESIELQNSL VVDEEKGELS PVPPNVPLSQ ECVTKGAMEL FTLQLPLSCE
1900
1901
AEKQPELELP TAQLPLDDKM DPLSLGVSQK AQESMCTEDM RKSSCVESFD
1950
1951
DQRRMSLHLH GADCDPKTQN EMNICEEEFV EYKNRDAISA LMPLFSEEES
2000
2001
SDGSKHNNGL PDHISAQLQN TYTLKAFTVG SKCVVWSSLR NTWSKCEILE
2050
2051
TAEEGTRVLN LSNGMEEIVN PENVWNGIPK LDKSPPEKRG LEVMEI    
2096
 

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Checksums:
CRC64:19FED65D6FE68E44
MD5:b49b52bad9389693423187c71010f918

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;