Summary
This is the summary of UniProt entry TDRD6_HUMAN (O60522).
| Description: | Tudor domain-containing protein 6 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
| Length: | 2096 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 2 |
| Pfam | TUDOR | 26 | 133 |
| low_complexity | n/a | 170 | 184 |
| Pfam | TUDOR | 246 | 380 |
| disorder | n/a | 287 | 291 |
| disorder | n/a | 294 | 310 |
| low_complexity | n/a | 448 | 468 |
| disorder | n/a | 452 | 467 |
| Pfam | TUDOR | 483 | 604 |
| disorder | n/a | 692 | 694 |
| disorder | n/a | 696 | 724 |
| Pfam | TUDOR | 768 | 886 |
| Pfam | TUDOR | 982 | 1102 |
| disorder | n/a | 1176 | 1177 |
| disorder | n/a | 1249 | 1250 |
| disorder | n/a | 1254 | 1255 |
| disorder | n/a | 1262 | 1265 |
| disorder | n/a | 1268 | 1269 |
| Pfam | TUDOR | 1301 | 1422 |
| Pfam | TUDOR | 1515 | 1638 |
| disorder | n/a | 1754 | 1756 |
| disorder | n/a | 1764 | 1765 |
| disorder | n/a | 1772 | 1773 |
| disorder | n/a | 1779 | 1781 |
| disorder | n/a | 1830 | 1837 |
| disorder | n/a | 1841 | 1844 |
| disorder | n/a | 1846 | 1848 |
| disorder | n/a | 1862 | 1878 |
| disorder | n/a | 1904 | 1933 |
| disorder | n/a | 1957 | 1963 |
| disorder | n/a | 1993 | 2014 |
| disorder | n/a | 2060 | 2063 |
| disorder | n/a | 2074 | 2082 |
| disorder | n/a | 2086 | 2096 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O60522. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MCSTPGMPAP GASLALRVSF VDVHPDVIPV QLWGLVGERR GEYLRLSREI
50 51
QEAAATRGQW ALGSASASPG ELCLVQVGLL WHRCRVVSRQ AQESRVFLLD
100 101
EGRTITAGAG SLAPGRREFF NLPSEVLGCV LAGLVPAGCG AGSGEPPQHW
150 151
PADAVDFLSN LQGKEVHGCV LDVLLLHRLV LLEVPDVFQQ MRELGLARRV
200 201
PDSLFRSLLE RYLTAATASV GSGVPVLSRV PLKQKQPGLD YFYPQLQLGV
250 251
TEAVVITQVC HPHRIHCQLR SVSQEIHRLS ESMAQVYRGS TGTGDENSTS
300 301
ATWEEREESP DKPGSPCASC GLDGHWYRAL LLETFRPQRC AQVLHVDYGR
350 351
KELVSCSSLR YLLPEYFRMP VVTYPCALYG LWDGGRGWSR SQVGDLKTLI
400 401
LGKAVNAKIE FYCSFEHVYY VSLYGEDGIN LNRVFGVQSC CLADRVLQSQ
450 451
ATEEEEPETS QSQSPAEEVD EEISLPALRS IRLKMNAFYD AQVEFVKNPS
500 501
EFWIRLRKHN VTFSKLMRRM CGFYSSASKL DGVVLKPEPD DLCCVKWKEN
550 551
GYYRAIVTKL DDKSVDVFLV DRGNSENVDW YDVRMLLPQF RQLPILAVKC
600 601
TLADIWPLGK TWSQEAVSFF KKTVLHKELV IHILDKQDHQ YVIEILDESR
650 651
TGEENISKVI AQAGYAKYQE FETKENILVN AHSPGHVSNH FTTESNKIPF
700 701
AKTGEGEQKA KRENKTTSVS KALSDTTVVT NGSTELVVQE KVKRASVYFP
750 751
LMQNCLEIKP GSSSKGELEV GSTVEVRVSY VENPGYFWCQ LTRNIQGLKT
800 801
LMSDIQYYCK NTAAPHQRNT LACLAKRTVN RQWSRALISG IQSVEHVNVT
850 851
FVDYGDREMV SVKNIYSISE EFLKVKAQAF RCSLYNLIQP VGQNPFVWDV
900 901
KAIQAFNEFI DNAWQKNLEL KCTIFALASI NEELFNIVDL LTPFQSACHF
950 951
LVEKRLARPV KLQKPLESSV QLHSYFYSTH DMKIGSEELV YITHIDDPWT
1000 1001
FYCQLARNAN ILEQLSCSIT QLSKVLLNLK TSPLNPGTLC LAKYTDGNWY
1050 1051
RGIVIEKEPK KVFFVDFGNI YVVTSDDLLP IPSDAYDVLL LPMQAVRCSL
1100 1101
SDIPDHIPEE VVVWFQETIL DKSLKALVVA KDPDGTLIIE LYGDNIQISA
1150 1151
SINKKLGLLS YKDRIRKKES EVLCSTTETL EEKNENMKLP CTEYLSKSVG
1200 1201
YKLPNKEILE ESYKPQINSS YKELKLLQSL TKTNLVTQYQ DSVGNKNSQV
1250 1251
FPLTTEKKEE ISAETPLKTA RVEATLSERK IGDSCDKDLP LKFCEFPQKT
1300 1301
IMPGFKTTVY VSHINDLSDF YVQLIEDEAE ISHLSERLNS VKTRPEYYVG
1350 1351
PPLQRGDMIC AVFPEDNLWY RAVIKEQQPN DLLSVQFIDY GNVSVVHTNK
1400 1401
IGRLDLVNAI LPGLCIHCSL QGFEVPDNKN SKKMMHYFSQ RTSEAAIRCE
1450 1451
FVKFQDRWEV ILADEHGIIA DDMISRYALS EKSQVELSTQ VIKSASSKSV
1500 1501
NKSDIDTSVF LNWYNPEKKM IRAYATVIDG PEYFWCQFAD TEKLQCLEVE
1550 1551
VQTAGEQVAD RRNCIPCPYI GDPCIVRYRE DGHYYRALIT NICEDYLVSV
1600 1601
RLVDFGNIED CVDPKALWAI PSELLSVPMQ AFPCCLSGFN ISEGLCSQEG
1650 1651
NDYFYEIITE DVLEITILEI RRDVCDIPLA IVDLKSKGKS INEKMEKYSK
1700 1701
TGIKSALPYE NIDSEIKQTL GSYNLDVGLK KLSNKAVQNK IYMEQQTDEL
1750 1751
AEITEKDVNI IGTKPSNFRD PKTDNICEGF ENPCKDKIDT EELEGELECH
1800 1801
LVDKAEFDDK YLITGFNTLL PHANETKEIL ELNSLEVPLS PDDESKEFLE
1850 1851
LESIELQNSL VVDEEKGELS PVPPNVPLSQ ECVTKGAMEL FTLQLPLSCE
1900 1901
AEKQPELELP TAQLPLDDKM DPLSLGVSQK AQESMCTEDM RKSSCVESFD
1950 1951
DQRRMSLHLH GADCDPKTQN EMNICEEEFV EYKNRDAISA LMPLFSEEES
2000 2001
SDGSKHNNGL PDHISAQLQN TYTLKAFTVG SKCVVWSSLR NTWSKCEILE
2050 2051
TAEEGTRVLN LSNGMEEIVN PENVWNGIPK LDKSPPEKRG LEVMEI
2096
Show the unformatted sequence. |
| Checksums: |
CRC64:19FED65D6FE68E44
MD5:b49b52bad9389693423187c71010f918
|
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
