Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
18  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: UGDH_HUMAN (O60701)

Summary

This is the summary of UniProt entry UGDH_HUMAN (O60701).

Description: UDP-glucose 6-dehydrogenase
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 494 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam UDPG_MGDP_dh_N 5 195
disorder n/a 179 183
Pfam UDPG_MGDP_dh 214 309
Pfam UDPG_MGDP_dh_C 332 447
disorder n/a 478 494

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O60701. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MFEIKKICCI GAGYVGGPTC SVIAHMCPEI RVTVVDVNES RINAWNSPTL
50
51
PIYEPGLKEV VESCRGKNLF FSTNIDDAIK EADLVFISVN TPTKTYGMGK
100
101
GRAADLKYIE ACARRIVQNS NGYKIVTEKS TVPVRAAESI RRIFDANTKP
150
151
NLNLQVLSNP EFLAEGTAIK DLKNPDRVLI GGDETPEGQR AVQALCAVYE
200
201
HWVPREKILT TNTWSSELSK LAANAFLAQR ISSINSISAL CEATGADVEE
250
251
VATAIGMDQR IGNKFLKASV GFGGSCFQKD VLNLVYLCEA LNLPEVARYW
300
301
QQVIDMNDYQ RRRFASRIID SLFNTVTDKK IAILGFAFKK DTGDTRESSS
350
351
IYISKYLMDE GAHLHIYDPK VPREQIVVDL SHPGVSEDDQ VSRLVTISKD
400
401
PYEACDGAHA VVICTEWDMF KELDYERIHK KMLKPAFIFD GRRVLDGLHN
450
451
ELQTIGFQIE TIGKKVSSKR IPYAPSGEIP KFSLQDPPNK KPKV      
494
 

Show the unformatted sequence.

Checksums:
CRC64:9C9DA5E1227D65CC
MD5:1ab228ec404807ff7a3f0c4d7a722716

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
UDPG_MGDP_dh 214 - 309 2Q3E A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
G 214 - 309 Jmol OpenAstexViewer
H 214 - 309 Jmol OpenAstexViewer
I 214 - 309 Jmol OpenAstexViewer
J 214 - 309 Jmol OpenAstexViewer
K 214 - 309 Jmol OpenAstexViewer
L 214 - 309 Jmol OpenAstexViewer
2QG4 A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
G 214 - 309 Jmol OpenAstexViewer
H 214 - 309 Jmol OpenAstexViewer
3ITK A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
3KHU A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
3PRJ A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
3PTZ A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
3TDK A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
G 214 - 309 Jmol OpenAstexViewer
H 214 - 309 Jmol OpenAstexViewer
I 214 - 309 Jmol OpenAstexViewer
J 214 - 309 Jmol OpenAstexViewer
K 214 - 309 Jmol OpenAstexViewer
L 214 - 309 Jmol OpenAstexViewer
3TF5 A 213 - 308 Jmol OpenAstexViewer
B 213 - 308 Jmol OpenAstexViewer
C 213 - 308 Jmol OpenAstexViewer
4EDF A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
4RJT A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
5TJH A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
5VR8 A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
5W4X A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
6C4J A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
G 214 - 309 Jmol OpenAstexViewer
H 214 - 309 Jmol OpenAstexViewer
I 214 - 309 Jmol OpenAstexViewer
J 214 - 309 Jmol OpenAstexViewer
K 214 - 309 Jmol OpenAstexViewer
L 214 - 309 Jmol OpenAstexViewer
6C4K A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
6C58 A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
6C5A A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
6C5Z A 214 - 309 Jmol OpenAstexViewer
B 214 - 309 Jmol OpenAstexViewer
C 214 - 309 Jmol OpenAstexViewer
D 214 - 309 Jmol OpenAstexViewer
E 214 - 309 Jmol OpenAstexViewer
F 214 - 309 Jmol OpenAstexViewer
UDPG_MGDP_dh_C 332 - 447 2Q3E A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
G 332 - 447 Jmol OpenAstexViewer
H 332 - 447 Jmol OpenAstexViewer
I 332 - 447 Jmol OpenAstexViewer
J 332 - 447 Jmol OpenAstexViewer
K 332 - 447 Jmol OpenAstexViewer
L 332 - 447 Jmol OpenAstexViewer
2QG4 A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
G 332 - 447 Jmol OpenAstexViewer
H 332 - 447 Jmol OpenAstexViewer
3ITK A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
3KHU A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
3PRJ A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
3PTZ A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
3TDK A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
G 332 - 447 Jmol OpenAstexViewer
H 332 - 447 Jmol OpenAstexViewer
I 332 - 447 Jmol OpenAstexViewer
J 332 - 447 Jmol OpenAstexViewer
K 332 - 447 Jmol OpenAstexViewer
L 332 - 447 Jmol OpenAstexViewer
3TF5 A 331 - 446 Jmol OpenAstexViewer
B 331 - 446 Jmol OpenAstexViewer
C 331 - 446 Jmol OpenAstexViewer
4EDF A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
4RJT A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
5TJH A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
5VR8 A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
5W4X A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
6C4J A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
G 332 - 447 Jmol OpenAstexViewer
H 332 - 447 Jmol OpenAstexViewer
I 332 - 447 Jmol OpenAstexViewer
J 332 - 447 Jmol OpenAstexViewer
K 332 - 447 Jmol OpenAstexViewer
L 332 - 447 Jmol OpenAstexViewer
6C4K A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
6C58 A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
6C5A A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
6C5Z A 332 - 447 Jmol OpenAstexViewer
B 332 - 447 Jmol OpenAstexViewer
C 332 - 447 Jmol OpenAstexViewer
D 332 - 447 Jmol OpenAstexViewer
E 332 - 447 Jmol OpenAstexViewer
F 332 - 447 Jmol OpenAstexViewer
UDPG_MGDP_dh_N 103 - 195 6C5Z B 103 - 195 Jmol OpenAstexViewer
5 - 195 2Q3E A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
G 5 - 195 Jmol OpenAstexViewer
H 5 - 195 Jmol OpenAstexViewer
I 5 - 195 Jmol OpenAstexViewer
J 5 - 195 Jmol OpenAstexViewer
K 5 - 195 Jmol OpenAstexViewer
L 5 - 195 Jmol OpenAstexViewer
2QG4 A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
G 5 - 195 Jmol OpenAstexViewer
H 5 - 195 Jmol OpenAstexViewer
3ITK A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
3KHU A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
3PRJ A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
3PTZ A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
3TDK A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
G 5 - 195 Jmol OpenAstexViewer
H 5 - 195 Jmol OpenAstexViewer
I 5 - 195 Jmol OpenAstexViewer
J 5 - 195 Jmol OpenAstexViewer
K 5 - 195 Jmol OpenAstexViewer
L 5 - 195 Jmol OpenAstexViewer
3TF5 A 5 - 194 Jmol OpenAstexViewer
B 5 - 194 Jmol OpenAstexViewer
C 5 - 194 Jmol OpenAstexViewer
4EDF A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
4RJT A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
5TJH A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
5VR8 A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
5W4X A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
6C4J A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
G 5 - 195 Jmol OpenAstexViewer
H 5 - 195 Jmol OpenAstexViewer
I 5 - 195 Jmol OpenAstexViewer
J 5 - 195 Jmol OpenAstexViewer
K 5 - 195 Jmol OpenAstexViewer
L 5 - 195 Jmol OpenAstexViewer
6C4K A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
6C58 A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
6C5A A 5 - 195 Jmol OpenAstexViewer
B 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer
6C5Z A 5 - 195 Jmol OpenAstexViewer
C 5 - 195 Jmol OpenAstexViewer
D 5 - 195 Jmol OpenAstexViewer
E 5 - 195 Jmol OpenAstexViewer
F 5 - 195 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.