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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: S19A2_HUMAN (O60779)

Summary

This is the summary of UniProt entry S19A2_HUMAN (O60779).

Description: Thiamine transporter 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 497 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 8 26
Pfam Folate_carrier 28 458
transmembrane n/a 29 46
transmembrane n/a 76 95
transmembrane n/a 102 123
transmembrane n/a 129 149
transmembrane n/a 161 182
transmembrane n/a 188 208
disorder n/a 261 265
low_complexity n/a 261 272
transmembrane n/a 295 312
transmembrane n/a 332 354
transmembrane n/a 366 388
transmembrane n/a 394 413
transmembrane n/a 420 443
low_complexity n/a 429 442
transmembrane n/a 455 476
disorder n/a 496 497

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O60779. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDVPGPVSRR AAAAAATVLL RTARVRRECW FLPTALLCAY GFFASLRPSE
50
51
PFLTPYLLGP DKNLTEREVF NEIYPVWTYS YLVLLFPVFL ATDYLRYKPV
100
101
VLLQGLSLIV TWFMLLYAQG LLAIQFLEFF YGIATATEIA YYSYIYSVVD
150
151
LGMYQKVTSY CRSATLVGFT VGSVLGQILV SVAGWSLFSL NVISLTCVSV
200
201
AFAVAWFLPM PQKSLFFHHI PSTCQRVNGI KVQNGGIVTD TPASNHLPGW
250
251
EDIESKIPLN MEEPPVEEPE PKPDRLLVLK VLWNDFLMCY SSRPLLCWSV
300
301
WWALSTCGYF QVVNYTQGLW EKVMPSRYAA IYNGGVEAVS TLLGAVAVFA
350
351
VGYIKISWST WGEMTLSLFS LLIAAAVYIM DTVGNIWVCY ASYVVFRIIY
400
401
MLLITIATFQ IAANLSMERY ALVFGVNTFI ALALQTLLTL IVVDASGLGL
450
451
EITTQFLIYA SYFALIAVVF LASGAVSVMK KCRKLEDPQS SSQVTTS   
497
 

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Checksums:
CRC64:87A993E2B6FBFE96
MD5:659027fe9d91b2d210cf1d141f6c0f5d

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.