Summary
This is the summary of UniProt entry S19A2_HUMAN (O60779).
| Description: | Thiamine transporter 1 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
| Length: | 497 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| low_complexity | n/a | 9 | 27 |
| Pfam | Folate_carrier | 28 | 458 |
| transmembrane | n/a | 29 | 46 |
| transmembrane | n/a | 76 | 95 |
| transmembrane | n/a | 102 | 123 |
| transmembrane | n/a | 129 | 149 |
| transmembrane | n/a | 161 | 182 |
| transmembrane | n/a | 188 | 208 |
| disorder | n/a | 261 | 265 |
| low_complexity | n/a | 262 | 273 |
| transmembrane | n/a | 295 | 312 |
| transmembrane | n/a | 332 | 354 |
| transmembrane | n/a | 366 | 388 |
| transmembrane | n/a | 394 | 413 |
| transmembrane | n/a | 420 | 443 |
| low_complexity | n/a | 430 | 443 |
| transmembrane | n/a | 455 | 476 |
| disorder | n/a | 496 | 497 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O60779. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MDVPGPVSRR AAAAAATVLL RTARVRRECW FLPTALLCAY GFFASLRPSE
50 51
PFLTPYLLGP DKNLTEREVF NEIYPVWTYS YLVLLFPVFL ATDYLRYKPV
100 101
VLLQGLSLIV TWFMLLYAQG LLAIQFLEFF YGIATATEIA YYSYIYSVVD
150 151
LGMYQKVTSY CRSATLVGFT VGSVLGQILV SVAGWSLFSL NVISLTCVSV
200 201
AFAVAWFLPM PQKSLFFHHI PSTCQRVNGI KVQNGGIVTD TPASNHLPGW
250 251
EDIESKIPLN MEEPPVEEPE PKPDRLLVLK VLWNDFLMCY SSRPLLCWSV
300 301
WWALSTCGYF QVVNYTQGLW EKVMPSRYAA IYNGGVEAVS TLLGAVAVFA
350 351
VGYIKISWST WGEMTLSLFS LLIAAAVYIM DTVGNIWVCY ASYVVFRIIY
400 401
MLLITIATFQ IAANLSMERY ALVFGVNTFI ALALQTLLTL IVVDASGLGL
450 451
EITTQFLIYA SYFALIAVVF LASGAVSVMK KCRKLEDPQS SSQVTTS
497
Show the unformatted sequence. |
| Checksums: |
CRC64:87A993E2B6FBFE96
MD5:659027fe9d91b2d210cf1d141f6c0f5d
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
