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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: H2B1K_HUMAN (O60814)

Summary

This is the summary of UniProt entry H2B1K_HUMAN (O60814).

Description: Histone H2B type 1-K
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 126 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 33
low_complexity n/a 1 17
Pfam Histone 2 102
low_complexity n/a 20 34
disorder n/a 82 83
disorder n/a 85 87

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O60814. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPEPAKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSV YVYKVLKQVH
50
51
PDTGISSKAM GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR
100
101
LLLPGELAKH AVSEGTKAVT KYTSAK                          
126
 

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Checksums:
CRC64:FAF9279F44BE703D
MD5:1c724df7231b61e13d953d380e185d43

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Histone 31 - 102 2CV5 D 27 - 98 Jmol OpenAstexViewer
32 - 102 2CV5 H 28 - 98 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.